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Home > Molecule Pages > Glycoenzymes > GlcNAc Transferases > Core 2 GlcNAc Transferase 1
 
Core 2 (b1,6) N-acetylglucosaminyl Transferase - 1
 
PubMed Links

  1. Fukuda M, Schwientek T, and Clausen H (2002) Core2 acetylglocosaminyltransferase I and III, Chapter 18. In: Handbook of Glycosyltransferases and Their Related Genes (Taniguchi N, Honke K and Fukuda M, eds) 132-142.


  2. Hemmerich S, Leffler H Rosen SD (1995) Structure of the O-glycans in GlyCAM-1, an endothelial-derived ligand for L-selectin. J Biol Chem 270:12035-12047


  3. Machida E, Nakayama J, Amano J, Fukada M (2001) Clinicopathological Significance of Core 2 ,6-N-Acetylglucosaminyltransferase Messenger RNA Expressed in the Pulmonary Adenocarcinoma Determined by in Situ Hybridization. Cancer Res 61:2226-2231


  4. Priatel JJ, Chui D, Hiraoka N, Simmons CJ, Richardson KB, Page DM, Fukuda M, Varki NM, Marth JD (2000) The ST3Gal-I sialyltransferase controls CD8+ T lymphocyte homeostasis by modulating O-glycan biosynthesis [In Process Citation]. Immunity 12:273-283


  5. Schwientek T, Yeh JC, Levery SB, Keck B, Nerkx G, van Kessel AD, Fukuda M, Clausen H (2000) Control of O-Glycan Branch Formation:Molecular Cloning and Characterizaiton of a Novel Thymus Associated Core 2 ß1,6-N-acetylglucosaminyltransgerase. J Biol Chem 275:11106-11113


  6. Skrincosky D, Kain R, El-Battari A, Exner M, Kerjaschki D, Fukuda M (1997) Altered Golgi localization of core 2 1,6-N- acetylglucosaminyltransferase leads to decreased synthesis of branched O-glycans. J Biol Chem 272:22695-22702


  7. Tsuboi S Fukuda M (1997) Branched O-linked oligosaccharides ectopically expressed in transgenic mice reduce primary T-cell immune responses. Embo J 16:6364-6373


  8. Wilkins PP, McEver RP Cummings RD (1996) Structures of the O-glycans on P-selectin glycoprotein ligand-1 from HL- 60 cells. J Biol Chem 271:18732-18742


  9. Yeh JC, Ong E, Fukuda M (1999) Molecular cloning and expression of a novel 1, 6-N- acetylglucosaminyltransferase that forms core 2, core 4, and I branches. J Biol Chem 274:3215-3221


  10. Yeh JC, Hiraoka N, Petryniak B, Nakayama J, Ellies L, Rabuka D, Hindsgaul O, Marth J, Lowe J, Fukuda M (2001) Novel Sulfated Lymphocyte Homing Receptors and Their Control by a Core1 Extension 1, 3-N- Acetylglucosaminyltransferase. Cell 105:957-969


  11. Yen T, Macher B, Bryson S, Chang X, Tvaroska I, Tse R, Takeshita S, Lew A, Datti A (2003) Highly conserved cysteines of mouse core2 1,6-N-acetylglucosaminyltranserase I form a network of disulfide bonds and include a thiol that affects enzyme activity. J Biol Chem .In press.

Latest papers on Core 2 GlcNAcT-1 [Search Now]

Online Mendelian Inheritance in Man (OMIM) 600391
Locus Link 2650
Other Public Database links

CAZY, ExPASy (Nicezyme View), WIT , BRENDA,

 
 

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