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Postdoctoral Openings Currently there are two openings in the Hammond Group: 1-) Linear-Dendritic Drug Delivery Systems: Patchy Micellar Assembly
Seeking a Postdoctoral Associate
with synthetic polymer and/or materials experience and a strong interest
in integrating his/her skills with in vitro and in vivo
experimentation as part of a team investigating new block copolymer
drug, gene and siRNA delivery systems. A barrier to the effective
delivery of cancer chemotherapy drugs is the transport of the toxic drug
to specific tumor cells, ensuring high uptake of drug by cancer cells
while avoiding noncancerous ones. One means of accomplishing this method
is the use of ligand groups added to the exterior of a nano-scale drug
carrier; however, much is not understood about maximizing these ligand
interactions to achieve orders of magnitude improvements in efficacy and
reduced side effects. By attaching specific ligands on the surfaces of
drug containing nanoparticles, one can target cancer cells for
chemotherapy and potentially eliminate the dire side-effects of
chemotherapy. The way in which the ligand is presented on the surface –
in bunches or clusters or evenly distributed – may greatly impact the
effectiveness of targeting. The systems designed in this NIH funded
project will enable precise tuning of ligand presentation so as to
greatly enhance the ability to target tumor cells directly, thus greatly
lowering the amount of drug needed. We will also investigate unique and
new peptide ligand systems that enable highly specific tumor and tumor
vasculature targeting in collaborations with other research groups at
MIT within the Koch Institute of Integrative Cancer Research. Announcing a Postdoctoral Associate position in the Hammond research group in the Chemical Engineering Department at MIT. The work would be primarily focused on the selective adsorption, deposition and patterning of thin films using polyion layer-by-layer adsorption, microcontact printing, nanopatterning, and using materials systems such as colloids, inorganic clusters, nanotubes and biotemplates for inorganic systems. This work would explore the design and assembly of photovoltaic devices as part of the MIT Energy Initiative. For all inquiries please send your CV, a brief research summary, and a cover letter indicating your research interests to hammond@mit.edu |
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