Publications from the Laboratory

Publications
From the Laboratory

Publications (1994-1998)
  1. Pulver, A., Karayiorgou, M., Wolyniec, P., Lasseter, V.K., Kasch, L., Antonarakis, S., Housman, D., Kazazian, H.H., Meyers, D., Nestadt, G., Ott, J., Lamacz, M., Liang, K-L., Hanfelt, J., Ullrich, G., DeMarchi, N., Ramu, E., McHugh, P.R., Adler, L., Thomas, M., Carpender, W.T., Manschreck, T., Gordon, C.T., Kimberland, M., Babb, R., Puck, J. and Childs, B. (1994) A Sequential Strategy to Identify a Susceptibility Gene for Schizophrenia: Report of a Potential Linkage on Chromosome 22q12-q13.1 Part 1. Amer. J. of Med. Gen. 54: 36-43.

  2. Munroe, D.M., Haas, M., Bric, E., Whitton, T., Aburatani, H., Hunter, K., Ward, D. and D.E. Housman. (1994) IRE-Bubble PCR: A Rapid Method for Efficient and Reproductive Amplification of Human Genomic DNA Sequences and Complex Sources. Genomics 19: 506-514.

  3. Pulver, A., Karayiorgou, M., Lasseter, V.K., Wolyniec, P., Kasch, L., Antonarakis, S., Housman, D., Kazazian, H.H., Meyers, D., Nestadt, G., Ott, J., Liang, K-L., Lamacz, M., Thomas, M., and Childs, B. (1994) Follow-up of A Report of a Potential Linkage for Schizophrenia on Chromosome 22q12-q13.1, Part 2. Amer. J. of Med. Gen. 54: 44-50.

  4. Hunter, K.W., Ontiveros, S.D., Watson, M.L., Stanton, V.P., Guttierez, P., Bhat, D., Rochelle, J., Graw, S., Ton, C.,, Schalling, M., Aburatani, H., Brown, S.D.M., Seldin, M. and Housman, D.E. (1994) Rapid and Efficient Construction of Yeast Artificial Chromosome Contigs in the Mouse Genome Utilizing Interspersed Repetitive Sequence PCR (IRS-PCR): Generation of a 5cM, >5 Megabase Contig on Mouse Chromosome 1. Mammalian Genome 5:597-607

  5. Ambrose, C., James, M., Barnes, G., Lin, C., Bates, G., Altherr, M., Duyao, Mabel, Groot, N., Church, D., Wasmuth, J., Lerach, H., Housman, D., Buckler, A., Gusella, J.F. and MacDonald, M. (1994) A Novel G Protein-Coupled Receptor Kinase Cloned from 4p16.3. Human Molecular Genetics 1:697-703.

  6. Lowe, S.W., Bodis, S., Bardeesy, N., McClatchey, A., Remington, L., Ruley, H.E., Fisher, D.E., Jacks, T., Pelletier, J. and Housman, D.E. (1994) Apoptosis and the Prognostic Significance of p53 Mutation. Cold Spring Harbor Sym. Quant. Bio. 59:419-426.

  7. Lowe, S.W., Bodis, S., McClatchey, A., Remington, L., Ruley. H.E., Fisher, D.E., Housman, D.E. and Jacks, T. (1994) p53 Status and the Efficacy of Cancer Therapy in Vivo. Science 266:807-810.

  8. Polakiewicz, R.D., Munroe, D.J., Jani Sait, S.N., Tycowski, K.T., Nowak, N.J., Shows, T.B., Housman, D.E., Page, D.C. Mapping of ribosomal protein S3 and internally nested snoRNA U15A gene to human chromosome 11q13.3q13.5. Genomics. 25:577-580.

  9. Higgins, M.J., Smilinich, N.J., Sait, S., Koenig, A., Pongratz, J., Gessler, M., Richard III, C.W., James, M.R., Sanford, J.P., Kim, B.-W., Cattelane, J., Nowak, N.J., Winterpacht, A., Zabel, B.U., Munroe, D.J., Bric, E., Housman, D.E., Jones, C., Nakamura, Y., Gerhard, D.S., Shows, T.B. (1994) An Ordered NotI Fragment Map of Human Chromosome Band 11p15. Genomics 23: 211-222.

  10. Coleman, A., Fountain, J.W., Nobori, T., Olopade, O.I., Robertson, G., Housman, D.E., Lugo, T.G. (1994) Distinct deletions of chromosome 9p associated with melanoma versus glioma, lung cancer, and leukemia. Cancer Research 54:344-348.

  11. Glaser, T., Ton, C.C., Mueller, R., Petzl-Erler, M.L., Oliver, C., Nevin, N.C., Housman, D.E., Maas, R.L. (1994) Absence of PAX6 gene mutations in Gillespie syndrome (partial aniridia, cerebellar ataxia, and mental retardation). Genomics, 19:145-148.

  12. Taneja, K.L., McCurrach, M., Schalling, M., Housman, D.E., Singer, R.H. (1995). Foci of trinucleotide repeat transcripts in nuclei of myotonic dystrophy cells and tissues. Journal of Cell Biology 128:995-1002.

  13. McCarthy, L., Hunter, K., Schalkwyk, L., Riba, L., Anson, S. Mott, R., Newell, W., Bruley, C., Bar, I., Ramu, E., Housman, D.E., Cox, R., Lehrach, H. (1995) Efficient high resolution genetic mapping of mouse IRS-PCR products, towards integrated genetic and physical mapping of the mouse genome. Proc. Natl. Acad. Sci. USA 92:5302-5306.

  14. Munroe, D.J., Loebbert, R., Bric, E., Whitton, T., Prawitt, D., Vu, D., Buckler, A., Winterpacht, A., Zabel, B. and Housman, D.E. (1995) Systematic screening of an arrayed cDNA library by PCR. Proc. Natl. Acad. Sci.92:2209-2213.

  15. Cai, W., Aburatani, H., Housman, D.E., Wang, Y-K. and Schwartz, D.C. (1995). Ordered restriction endonuclease maps of yeast artificial chromsomes created by optical mapping on surfaces. Proc. Natl. Acad. Sci. USA 92:5164-5168

  16. Nakagama, H., Heinrich, G., Pelletier, J., and Housman, D.E. (1995). Sequence and structural requirements for high affinity DNA binding by the WT1 gene product. Molecular and Cellular Biology 15:1489-1498.

  17. Russell, M.W., Dick III, M., Campbell, R. M., Munroe, D.J., Bric, E., Housman, E.E., Collins F.S., and L.C.Brody (1995). Recombination analysis in two 11p15-linked Romano-Ward Long QT Syndrome (RWLQTS) families: localization of the RWLQTS gene to the interval between tyrosone hydroxylase (TH) and D11S1349. American Journal of Human Genetics 57:503-507.

  18. Housman, D.E. (1995) Human DNA Polymorphism. New England Journal of Medicine 332: 318-320.

  19. Housman, D.E. (1995) DNA on trial - The molecular basis of DNA fingerprinting. New England Journal of Medicine 332:534-535.

  20. Karayiorgou, M., Morris, M.A., Morrow, B., Shprintzen, R.J., Goldberg, R., Borrow, J., Gos, A., Nestadt, G., Wolyniec, P.S., Lasseter, V.K., Eisen, H., Childs, B., Kazazian, H.H., Kucherlapati, R., Antonarkis, S.E., Pulver, A.E., and D.E. Housman. (1995). Schizophrenia susceptibility associated with interstitial deletions of chromosome 22q11. Proc. Natl. Acad. Sci. 92:7612-7616.

  21. Haluska, F.G. and David E. Housman. (1995) Recent advances in the molecular genetics of malignant melanoma. Cancer Surveys 25: 277-292.

  22. Moffett, P., Bruening, W., Nakagama, H., Bardeesy, N., Housman, D., Housman, D.E., and J.Pelletier. (1995) Antagonism of WT1 activity by self-association. Proc.Natl.Acad.Sci. USA 92:11105-11109.

  23. Flores, J.F., Walker, G.J., Glendening, J.M., Haluska, F.G., Castresana, J.S., Rubio, M-P., Pastorfide, G.C., Boyer, L.A., Kao, W.H., Bulyk, M.L., Barnhill, R.L., Hayward, N.K., Housman, D.E., and Fountain, J.W. Loss of the p16INK4a and p15INK4b genes, as well as neighboring 9p21 markers, in sporadic melanoma. Cancer Research 56 (in press).

  24. Munroe, D. J., Prawitt, D., Bric, E., Byrd, P., Whitton, T., Vu, D, Loebbert, R., Sait, S.N., Nowak, N.J., Winterpacht, A., Zabel, B. U., Shows, T. B., Deaven, L., Evans, G., and David E. Housman (1995). Rapid assembly of cosmid contigs from YACs. Genome Research, (Submitted)

  25. Dong, W-F., Xu, Y., Hu, Q., Munroe, D., Minowada, J., Housman, D., and M.D. Minden. Molecular characterization of a chromosome translocation breakpoint t(11;14)(p13;q11) from the cell line KOPT-K1. Leukemia 9:1812-7.

  26. Hsu, S.Y., Kubo, M., Chun, S.Y., Haluska, F.G., Housman, D.E., Hsueh, A.J. (1995) Wilms' tumor protein WT1 as an ovarian transcription factor: decreases in expression during follicle development and repression of inhibin-alpha gene promoter. Mol. Endocrinol. 9: 1356-66

  27. Qin, S., Sait, S., Zhang, J., Nowak, N., Cheng, Y., Li, L., Higgens, M., Munroe, D. J., Bric, E., Housman, D., Gerhardt, D., Evans, G., Weber, B., Gaudary, P., and T. Shows. A YAC contig of human chromosome 11. Proc.Natl.Acad.Sci.USA 93:3149-3154.

  28. Liu, J., Stanton, V.P. Jr., Fujiwara, T.M., Wang, J.X., Rezonzew, R., Crumley, M.J., Morgan, K., Gros, P., Housman, D.E., Schurr, E. (1995) Large-scale cloning of human chromosome 2-specific yeast artificial chromosomes (YACs) using an interspersed repetitive sequences (IRS)-PCR approach. Genomics 26:178-191.

  29. Housman, D.E. (1995) Gain of glutamines, gain of function? Nature Genetics 10:3-4.

  30. Reddy, S., Smith, D.B.J., Rich, M.M., Leferovich, J.M., Reilly, P., Davis, B., Tran, K., Rayburn, H., Bronson, R., Cros, D., Balice-Gordon, R.J. and D.E. Housman. (1996) Mice lacking the myotonic dystrophy protein kinase develop a late onset progressive myopathy. Nature Genetics 13:325-35.

  31. Graeber, T.G., Osmanian, C., Jacks, T., Housman, D.E., Koch, C.J., Lowe, S.W. and A.J. Giaccia. (1996) Hypoxia, apoptosis and p53 tumor development. Nature 379: 88-91

  32. Aburatani, H., Stanton, V.P. Jr., and Housman, D.E. (1996) High resolution physical mapping by combined Alu-hybridization/PCR screening: construction of a Yeast Artificial Chromosome map covering 31 cM in 3p21-p14. Proc. Natl. Acad. Sci. USA 93: 4474-4479.

  33. Manenti, G., Gariboldi, M., Elango, R., Fiorino, A., De Gregorio, L., Falvella, F.S., Hunter, K., Housman, D., Pierotti, M.A., and Dragani, T.A. (1996) Genetic mapping of a pulmonary adenoma resistance locus (Par1) in the mouse. Nature Genetics 12/4: 455-457.

  34. Hunter, K., Riba, L.,Schalkwyk, L., Clark, M., Resenchuk,S., Beeghly, A., Su, J., Tinkov, F., Lee, P., Elango, R., Lehrach, H., and Housman, D.E. (1996) Towards the construction of integrated physical and genetic maps of the mouse genome utilizing interspersed repetitive sequence PCR (IRS-PCR) genomics. Genome Research 6:290-299

  35. Haluska, F.G., Fountain, J.W., Alberta, J., Rivera, M., Stanton, V.P., and Housman, D.E. Construction of a 5 megabase YAC contig on chromosome 9p21-22. (Submitted)

  36. Borrow, J., Shearman, A.M., Stanton, V.P., Jr., Becher, R., Collins, T., Williams, A.J., Dube, I., Katz, F., Kwong, Y.L., Morris, C., Kazuma, Ohyashiki, Toyama, K., Rowley, J., and Housman, D.E. (1996) The t(7;11)(p15;p15) translocation in acute myeoloid leukaemia fuses the genes for nucleoporin NUP98 to class I homeoprotein HOXA9. Nature Genetics 12:159-167.

  37. Russell, M.W., Munroe, D.J., Bric, E., Housman, D.E., Dietz-Band, J., Riethman, H.C., Collins, F.S., and Brody, L.C. (1996) A 500 kb physical map from the Harvey ras-1 gene to the 11p telomere. Genomics 35:353-360

  38. Shearman, A.M., Hudson, T.J., Andresen, J.M., Wu, X., Sohn, R.L., Haluska, F., Housman, D.E. and Weiss, J.S. (1996) The gene for Schnyder's crystalline corneal dystrophy maps to human chromosome 1p34.1-p36. Human Molecular Genetics 5:1667-1672.

  39. Haluska, F.G., Thiele, Carol, Goldstein, A., Fountain, J.W. and Housman, D.E. Lack of phospholipase A2 mutations in colon cancer, melanoma and neuroblastoma cell lines. (submitted)

  40. Dackowski, W.R., Connors, T.D., Bowe, A.E., Stanton, V.P. Jr., Housman, D.E., Doggett, N.A., Landes, G.M., and Klinger, K.W. (1996) The region surrounding the PKD1 gene: A 700kb P1 contig from a YAC-deficient interval. Genome Research 6: 515-524.

  41. Elango, R., Riba, L., Housman, D.E. and Hunter, K. (1996) Generation and mapping of M.spretus strain-specific markers for rapid genomic scanning. Mammalian Genome 7:340-343.

  42. Pulver, A.E., Wolyniec, P.S., Housman, D.E., Kazazian, H.H., Anonarakis, S.E., Nestadt, G., Lasseter, V.K., McGrath, J.A., Dombroski, B., Karayiorgou, M., Ton, C., Blouin, J-L., and L. Kempf. (1996) The Johns Hopkins University Collaborative Schizophrenia Study: an Epidemiologic-genetic approach to test the heterogeneity hypothesis and identify schizophrenia susceptibility genes. (submitted)

  43. Borrow, J., Stanton, V.P.Jr., Andresen, J.M., Becher, R., Behm., F.G., Chaganti, R.S.K., Civin, C.I., Disteche, C., Dube, I., Frischauf, I., Horsman, D., Mitelman, F., Volinia, S., Watmore, A.E.and D.E. Housman (1996) The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein. Nature Genetics 14:33-41.

  44. Karayiorgou, M., Gogos, J.A., Galke, B.L., Woyniec, P.S., Nestadt, G., Anonarakis, S.E., Kazazian, H.H., Housman, D.E. and A.E. Pulver Identification of sequence variants and of the role of the COMT gene in schizophrenia susceptibility. Biological Psychiatry (submitted)

  45. Reddy, P.S. and D.E. Housman (1997) The complex pathology of trinucleotide repeats. Curr. Opin. Cell Biol. 9: 364-372

  46. Davis, B.M., McCurrach, M.E., Taneja, K.L., Singer, R.H. and D.E. Housman (1997) Expansion of a CUG trinucleotide repeat in the 3' untranslated region of myotonic dystrophy protein kinase transcripts results in nuclear retention of transcripts. Proc. Natl. Acad. Sci. USA 94:7388-7393

  47. Sobulu, O.M., Borrow, J., Tornek, R., Reshmi, S., Harden, A., Schlegelberger, B., Housman, D.E., Doggett, N.A., Rowley J.D. and J. Zeleznik-Le (1997) MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute. Proc. Natl. Acad. Sci. USA 94 (8732-7).

  48. Haluska, F.G., Thiele, C., Goldstein, A., Tsao, H., Benoit, E.P., and D.E. Housman. (1997) Lack of phospholipase A2 mutations in neuroblastoma, melanoma, and colon-cancer cell lines. Int. J. Cancer 72:337-339.

  49. Rodriguez, P., Munroe, D., Prawitt, D. Chu, LL, Bric, E., Kim, J., Reid, L.H., Davies, C., Nakagama, H., Loebbert, R., Winterpacht, A., Petruzzi, MJ., Higgins, M.J., Nowak, N., Evans, G., Shows, T., Weissman, B.E., Zabel, B., Housman, D.E. and J. Pelletier. (1997) Functional characterization of human nucleosome assembly protein -2 (NAP1L4) suggests a role as a histone chaperone. Genomics 44: 253-65

  50. Das, M., Chu, L.L., Ghahremani, M., Abrams-Ogg, T., Roy, M.S., Housman, D.E., and J. Pelletier. (1998) Characterization of an abundant short interspersed nuclear element (SINE) present in Canis familiaris. Mammalian Genome 9:64-69.
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