Department of Biology
Massachusetts Institute of Technology
Howard Hughes Medical Institute
McGovern Institute for Brain Research


Abstracts: 1999-2011


Choose the worm meeting:

18th International C. elegans Conference, June, 2011
University of California, Los Angeles, CA

C. elegans: Development and Gene Expression , June, 2010
EMBL Heidelberg, Germany

C. elegans Neuronal Development, Synaptic Function & Behavior, June, 2010
University of Wisconsin-Madison, Madison, Wisconsin

17th International C. elegans Conference, June, 2009
University of California, Los Angeles, CA

C. elegans Aging, Stress and Pathogenesis Meeting
August, 2008
University of Wisconsin-Madison, Madison, Wisconsin

C. elegans Neuronal Development, Synaptic Function & Behavior, July, 2008
University of Wisconsin-Madison, Madison, Wisconsin

C. elegans Development & Evolution Meeting, June, 2008
University of Wisconsin-Madison, Madison, Wisconsin

16th International C. elegans Conference, June, 2007
University of California, Los Angeles, CA

Neuronal Development, Synaptic Function & Behavior
C. elegans Topic Meeting #2, July, 2006
University of Wisconsin-Madison, Madison, Wisconsin

Development & Evolution
C. elegans Topic Meeting #1, June 2006
University of Wisconsin-Madison, Madison, Wisconsin

15th International C. elegans Conference, June, 2005
University of California, Los Angeles, CA

East Coast C. elegans Meeting, June, 2004
Yale University, New Haven, CT

14th International C. elegans Conference, June, 2003
University of California, Los Angeles, CA

West Coast C. elegans Meeting, August, 2002
University of California, San Diego, CA


East Coast C. elegans Meeting, June, 2002
University of New Hampshire, Durham, NH


European C. elegans Meeting, May, 2002
Paestum, Italy


13th International C. elegans Meeting, June, 2001
University of California, Los Angeles, CA


East Coast C. elegans Meeting, June, 2000
Emory University, Atlanta, GA


12th International C. elegans Meeting, June, 1999
University of Wisconsin, Madison, WI


18th International C. elegans Conference, June, 2011
University of California, Los Angeles, CA

Genetic and Neural Pathways Underlying Light-induced Inhibition of Pharyngeal Pumping by C. elegans.
Nikhil Bhatla and Bob Horvitz

The microRNA mir-71 Acts in the Ectoderm to Promote Germline-Mediated Longevity by Regulating DAF-16 Activity.
Konstantinos Boulias and Bob Horvitz

In vivo Regulation of the Alternative Splicing of the Pro- and Anti-Apoptotic Gene ced-4.
Anna Corrionero and Bob Horvitz

Cell Extrusion Is a Caspase-Independent Mechanism for Programmed Cell Elimination in C. elegans.
Dan Denning, Victoria Hatch and Bob Horvitz

Use of Single-molecule FISH To Determine Expression Patterns and Functions of C. elegans Lysine Methyltransferases.
Christoph G Engert, Alexander van Oudenaarden and Bob Horvitz

The Sp1 Family Transcription Factor SPTF-3 Promotes M4 Sister Cell Death through egl-1 Expression in the M4 Sister Cell.
Takashi Hirose and Bob Horvitz

sli-1 Cbl Opposes the Engulfment of Apoptotic Cells.
Michael E. Hurwitz, Courtney Anderson and Bob Horvitz

A Screen for Genes Involved in Engulfment-Dependent Cell Death.
Holly L. Johnsen and H.R. Horvitz

Sensory Nerve Ending Regeneration during Development of the C. elegans Dopaminergic PDE Neurons.
Xuemin Lu, Tori Hatch, Rita Droste and Robert Horvitz

Replication-Coupled Nucleosome Assembly Is Required to Generate a Bilateral Asymmetry in the C. elegans Nervous System.
Shunji Nakano, Bruce Stillman and Bob Horvitz

The Novel Conserved Gene C44B9.1 Regulates C. elegans Behavior through G Protein Signaling and Likely Regulates Synaptic Vesicle Release.
N. Paquin, A. Froehlich, D. Omura and H.R. Horvitz

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C. elegans: Development and Gene Expression, June, 2010
EMBL Heidelberg, Germany

PIG-1-controlled Asymmetric Cell Divisions promote the Caspase-independent Apoptosis of Cells that Are Shed from the C. elegans Embryo
Dan Denning, Victoria Hatch and Bob Horvitz

Elucidating the Roler of Putative Histone Lysine Methyltransferases in C. elegans by Combining Expression and Genetic Analyses
Christoph Engert, Bob Horvitz and Alexander van Oudenaarden

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C. elegans Neuronal Development, Synaptic Function & Behavior, June, 2010
University of Wisconsin-Madison, Madison, WI

Investigating C. elegans Learning as a Possible Approach to the Study of Consciousness
Nikhil Bhatla and Bob Horvitz

Three New Software Tools for Tracking Worms, Visualizing Neural Networks and Displaying Gene Structures
Nikhil Bhatla and Bob Horvitz

C44B9.1 Is a Novel Conserved Neuronal Protein Likely Involved in Synaptic Vesicle Exocytosis
Nicolas Paquin, Allan Froehlich, Daniel Omura and Bob Horvitz

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17th International C. elegans Conference, June, 2009
University of California, Los Angeles, CA

Investigating C. elegans Learning as a Possible Approach to the Study of Consciousness
Nikhil Bhatla and Bob Horvitz

The microRNA mir-71 Is Involved in the Regulation of Longevity and Stress Responses in C. elegans
Konstantinos Boulias and Bob Horvitz

The Conserved NAB family Transcriptional Co-factor mab-10 Acts with the Heterochronic Gene lin-29 to Regulate Terminal Differentiation in Hypodermal Lineages
David Harris and Bob Horvitz

egl-1-Dependent and Independent Pathways Cooperate to Control M4 Sister Cell Death
Takashi Hirose, Brendan Galvin and Bob Horvitz

ngn-1 and hlh-2 Are Required for a Left-Right Asymmetric Neurogenesis Decision
Shunji Nakano, Ronald Ellis and Bob Horvitz

Characterization of a Novel Conserved Neuronal Protein Possibly Involved in Synaptic Vesicle Exocytosis
Nicolas Paquin, Allan Froehlich, Daniel Omura and Bob Horvitz

The BAG Sensory Neurons are Activated by Environmental Carbon Dioxide
Niels Ringstad, Elissa Hallem, Paul Sternberg and Bob Horvitz

Inward Rectifier Potassium Channels Inhibit C. elegans Egg Laying and Locomotion
Niels Ringstad and Bob Horvitz

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C. elegans Aging, Stress and Pathogenesis Meeting
August, 2008
University of Wisconsin-Madison, Madison, Wisconsin

Analysis of the Role of MicroRNAs in the Control of C. elegans Aging
Konstantinos Boulias, Ezequiel Alvarez-Saavedra, Bob Horvitz

Genetic Screens for New Genes Involved in C. elegans Aging
Simona Tescu, Ala Berdichevsky, Bob Horvitz

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C. elegans Neuronal Development, Synaptic Function & Behavior, July, 2008
University of Wisconsin-Madison, Madison, Wisconsin

Reduction of Movement by flp-11, which Encodes FMRFamide-related Peptides
Nikhil Bhatla, Niels Ringstad, Bob Horvitz

Characterization of a Novel Conserved Protein Possibly Involved in Synaptic Vesicle Exocytosis
Allan Froehlich, Daniel Omura, Nicolas Paquin, Bob Horvitz

FLP-18 Neuropeptide Signaling Functions to Increase C. elegans Body Curvature
Yin Li, Niels Ringstad, Bob Horvitz

Some C. elegans Ligand-gated Chloride Channels Are Receptors for Biogenic Amines
Niels Ringstad, Namiko Abe, Bob Horvitz

A Pair of Presumptive Sensory Neurons Inhibits C. elegans Egg-laying Behavior
Niels Ringstad, Bob Horvitz

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C. elegans Development & Evolution Meeting, June, 2008
University of Wisconsin-Madison, Madison, Wisconsin

The Caspase Homolog csp-1 Promotes Programmed Cell Death in a Subset of Cells that Die During Development
Dan Denning, Victoria Hatch, Bob Horvitz

The Heterochronic Gene mab-10 Acts with lin-29 to Regulate Terminal Differentiation in Hypodermal Lineages
David Harris, Victoria Hatch, Bob Horvitz

A Genetic Pathway for M4 Sister Cell Death
Takashi Hirose, Brendan Galvin, Bob Horvitz

abl-1 Suppresses the Engulfment of Apoptotic Cells through a Novel Pathway that Contains abi-1
Mike Hurwitz, Pam Vanderzalm, Laird Bloom, Julia Goldman, Gian Garriga, Bob Horvitz

Pre-mRNA Splicing Factors and a Novel Nuclear Protein Interact to Regulate Rubberband Unc Gene Activity
Long Ma, H. Robert Horvitz

Two bHLH Transcription Factors Are Required for Breaking Symmetry in a Left-Right Asymmetric Cell Lineage
Shunji Nakano, Ronald Ellis, Bob Horvitz

A New Class A SynMuv Mutation Is a lin-3(gf) Allele that Causes Increased lin-3 mRNA Levels
Adam Saffer, Bob Horvitz

The BarH Class Homeodomain Gene ceh-30 Controls Sexually Dimorphic CEM Neuron Survival Independently of CED-9 Bcl-2
Hillel Schwartz, Bob Horvitz

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16th International C. elegans Conference, June, 2007
University of California, Los Angeles, CA

Analysis of the Role of MicroRNAs in the Control of C. elegans Aging
Konstantinos Boulias, Ezequiel A. Alvarez-Saavedra, Ala Berdichevsky, Bob Horvitz

The Perturbation of Genes that Regulate the Microtubule Cytoskeleton Causes the Appearance of Extra-Embryonic Anucleate Bodies
Dan Denning, Bob Horvitz

A Novel Conserved Gene that Might Be Involved in Synaptic Vesicle Release
Allan Froehlich, Bob Horvitz

mab-10, a Heterochronic Gene Required For the Terminal Differentiation of Hypodermal Cells and the Cessation of Molting, Encodes a Member of the NAB Family of Transcription Factors
David Harris, Bob Horvitz

CEH-34 is Required for M4 Sister Cell Death and Pharyngeal Development
Takashi Hirose, Bob Horvitz

abl-1 Opposes the Engulfment of Apoptotic Cells
Michael Hurwitz, Pam Vanderzalm, Laird Bloom, Julia Den Uyl, Gian Garriga, Bob Horvitz

FLP-18 Neuropeptide Signaling Can Modulate C. elegans Locomotion.
Yin Li, Niels Ringstad, Bob Horvitz

New Suppressors of unc-93(e1500sd) Locomotory Defects Affect Genes Encoding Critical pre-mRNA Splicing Factors
Long Ma, Bob Horvitz

Mutations that Restore Symmetry in a Left-Right Asymmetric Cell Lineage
Shunji Nakano, Ronald E. Ellis, Victoria Hatch, Bob Horvitz

Regulation of Dopamine Signaling in the Modulation of Locomotion
Robert O'Hagan, Bob Horvitz

A New Class A SynMuv Mutation is a lin-3(gf) Allele That Causes Increased lin-3 mRNA Levels
Adam Saffer, Bob Horvitz

Mutations in selected synMuv genes cause the green pharynx phenotype of transcriptional derepression
Hillel Schwartz, Dawn Wendell, Bob Horvitz

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Neuronal Development, Synaptic Function & Behavior
C. elegans Topic Meeting #2, July, 2006
University of Wisconsin-Madison, Madison, Wisconsin

SEROTONIN AND FLP-1 NEUROPEPTIDE SIGNALING MEDIATE THE ENHANCED SLOWING RESPONSE
Megan Higginbotham, Bob Horvitz

REGULATION OF DOPAMINE SIGNALING IN THE MODULATION OF LOCOMOTION
Robert O'Hagan, Bob Horvitz

INSULIN AND NPR-1 NEUROPEPTIDE SIGNALING MUTANTS ARE DEFECTIVE IN THE ENHANCED SLOWING RESPONSE INDUCED BY FOOD DEPRIVATION
Daniel Omura, Bob Horvitz

TWO DISTINCT CLASSES OF POTASSIUM CHANNELS INHIBIT C. ELEGANS EGG LAYING
Niels Ringstad, Bob Horvitz

A FMRF AMIDE NEUROPEPTIDE SIGNALING PATHWAY AND ACETYLCHOLINE NEGATIVELY REGULATE C. ELEGANS EGG-LAYING BEHAVIOR
Niels Ringstad, Bob Horvitz

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Development & Evolution
C. elegans Topic Meeting #1, June 2006
University of Wisconsin-Madison, Madison, Wisconsin

lst-3 NEGATIVELY REGULATES THE VULVAL CELL-FATE DECISION
Erik Andersen, Scott Clark, Melanie Worley, Bob Horvitz

ANALYSIS OF THE ROLE OF MICRORNAS IN C. ELEGANS AGING
Konstantinos Boulias, Ezequiel Alvarez-Saavedra, Ala Berdichevsky, Bob Horvitz

CHARACTERIZATION OF DETACHED CELLS IN EMBROYOS DEFECTIVE FOR PROGRAMMED CELL DEATH AND CORPSE ENGULFMENT
Dan Denning, Bob Horvitz

A SURVEY OF TRP CHANNELS FOR FUNCTION IN C. ELEGANS TEMPERATURE-REGULATED BEHAVIORS
Allan Froelich, Bob Horvitz

PROGRESS TOWARDS CLONING mab-10, A HETEROCHRONIC GENE REQUIRED FOR THE PROPER TIMING OF THE L4/ADULT TRANSITION IN MALES
David Harris, Bob Horvitz

A SCREEN FOR MUTANTS DEFECTIVE IN THE SPECIFICAITON OF M4 SISTER CELL DEATH
Takashi Hirose, Bob Horvitz

A SCREEN FOR GENES SYNTHETICALLY LETHAL WITH lin-35 RB
Michael Hurwitz, Julia Den Uyl, Bob Horvitz

GENETIC SCREEN FOR AND MOLECULAR CHARACTERIZATION OF NOVEL SUPPRESSORS OF MUTATIONS AFFECTING THE SUP-9/SUP-10/UNC-93 TWO-PORE DOMAIN K+ CHANNEL COMPLEX
Long Ma, Bob Horvitz

GENETIC SCREENS FOR GENES INVOLVED IN LEFT-RIGHT ASYMMETRIC PROGRAMMED CELL DEATH
Shunji Nakano, Bob Horvitz

THE ESSENTIAL CLASS A SYNMUV GENE lin-38 ENCODES A NOVEL ZINC-FINGER PROTEIN
Adam Saffer, Bob Horvitz

THE BARH CLASS HOMEODOMAIN GENE ceh-30 IS DIRECTLY REGULATED BY TRA-1 TO SPECIFY THE SEXUALLY DIMORPHIC SURVIVAL OF THE CEM NEURONS
Hillel Schwartz, Bob Horvitz

THE "GREEN PHARYNX" PHENOTYPE OF TRANSGENE MISEXPRESSION SHOWS SYNMUV GENES CAN ACT IN NOVEL COMBINATIONS IN CONTEXTS OTHER THAN VULVAL FATES
Hillel Schwartz, Bob Horvitz

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15th International C. elegans Conference, June, 2005
University of California, Los Angeles, CA

FUNCTIONAL ANALYSIS OF THE MICRORNA GENES OF C. ELEGANS: ROLES OF THE lin-4 AND let-7 FAMILIES OF MICRORNAS IN DEVELOPMENTAL TIMING
Allison L Abbott, Ezequiel Alvarez-Saavedra, Eric A Miska, Nelson C Lau, David P Bartel, Bob Horvitz, Victor Ambros

IDENTIFICATION AND CHARACTERIZATION OF C. ELEGANS AMINE-GATED CHLORIDE CHANNELS
Namiko Abe, Niels Ringstad, Bob Horvitz

OCTOPAMINE ACTS ANTAGONISTICALLY TO SEROTONIN IN THE MODULATION OF FOOD-DEPENDENT BEHAVIORS
Mark Alkema, Bob Horvitz

THE mir-35 FAMILY OF MICRORNAS ACT REDUNDANTLY IN EMBRYONIC DEVELOOPMENT IN C. ELEGANS
Ezequiel Alvarez-Saavedra, Eric A Miska, Allison L Abbott, Nelson C Lau, David P Bartel, Victor Ambros, Bob Horvitz

MET-1 AND MET-2, TWO PUTATIVE HISTONE METHYLTRANSFERASES ARE REDUNDANTLY REQUIRED FOR PROPER VULVAL CELL-FATE DETERMINATION IN C. ELEGANS
Erik Andersen, Bob Horvitz

CLONING AND CHARACTERIZATION OF SUPPRESSORS OF THE SYNTHETIC MULTIVULVA PHENOTYPE
Erik Andersen, Xiaowei Lu, Scott Clark, Bob Horvitz

CHARACTERIZATION OF ced-3-INDEPENDENT PROGRAMMED CELL DEATH
Dan Denning and Bob Horvitz

ANALYSIS OF MICRORNA INTERACTIONS WITH MRNA TARGET SITES IN THE C. ELEGANS NERVOUS SYSTEM
Dominic M. Didiano, Eric A Miska, Ezequiel Alvarez-Saavedra, Bob Horvitz, Oliver Hobert

AN ATTEMPT TO DEVELOOP HOMOLOGOUS GENE TARGETING IN C. ELEGANS USING POSITIVE/NEGATIVE SELECTION AND A STRAIN DEFICIENT IN NONHOMOLOGOUS END-JOINING
Allan Froehlich and Bob Horvitz

C. ELEGANS SYNMUV PROTEINS FORM AT LEAST TWO PUTATIVE CHROMATIN REGULATORY COMPLEXES
Melissa M Harrison, Craig Ceol, Xiaowei Lu, and Bob Horvitz

A NEW GENETIC SCREEN FOR HERMAPHRODITES WITH INAPPROPRIATELY SURVIVING CEM NEURONS
David Harris and Bob Horvitz

GENES INVOLVED IN SEROTONERGIC NEUROTRANSMISSION
Megan Higginbotham and Bob Horvitz

A SCREEN FOR GENES SYNTHETICALLY LETHAL WITH lin-35 RB
Michael E. Hurwitz, Bob Horvitz

GENETIC SCREEN FOR AND MOLECULAR CHARACTERIZATION OF NOVEL SUPPRESSORS OF THE SUP-9/SUP-10/UNC-93 TWO-PORE DOMAIN K+ CHANNEL COMPLEX
Long Ma, Bob Horvitz

FUNCTIONAL ANALYSIS OF THE MICRORNA GENES OF C. ELEGANS
Eric A Miska, Ezequiel Alvarez-Saavedra, Allison L Abbott, Andrew Hellman, Nelson Lau, David Bartel, Victor Ambros, Bob Horvitz

INSULIN AND NEUROPEPTIDE SIGNALING MUTANTS ARE DEFECTIVE IN THE ENHANCED SLOWING RESPONSE INDUCED BY FOOD DEPRIVATION
Daniel Omura and Bob Horvitz

INHIBITION OF C. ELEGANS EGG-LAYING BEHAVIOR BY NEUROPEPTIDE SIGNALING PATHWAYS
Niels Ringstad, Bob Horvitz

PROGRESS TOWARDS THE CLONING OF lin-38 AND IDENTIFICATION OF NOVEL CLASS A SYNMUV GENES
Adam Saffer, Ewa Davison, Bob Horvitz

THE BARH CLASS HOMEODOMAIN GENE ceh-30 IS DIRECTLY REGULATED BY TRA-1 TO SPECIFY THE SEXUALLY DIMORPHIC SURVIVAL OF THE CEM NEURONS
Hillel Schwartz, Bob Horvitz

THE "GREEN PHARYNX" PHENOTYPE OF TRANSGENE MISEXPRESSION SHOWS SYNMUV GENES ACTING IN DIFFERENT PROCESSES CAN ACT IN DIFFERENT COMBINATIONS
Hillel Schwartz, Dawn Wendell, Bob Horvitz

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East Coast C. elegans Meeting, June, 2004
Yale University, New Haven, CT

IDENTIFICATION AND CHARACTERIZATION OF C. ELEGANS AMINE-GATED CHLORIDE CHANNELS
Namiko Abe, Niels Ringstad, Bob Horvitz

OCTOPAMINE INHIBITS PHARYNGEAL PUMPING AND EGG LAYING AND STIMULATES LOCOMOTION.
Mark Alkema, Niels Ringstad, Bob Horvitz

THE let-7 AND mir-35 FAMILIES OF MICRORNAS EACH ACT REDUNDANTLY IN C. ELEGANS
Ezequiel Alvarez-Saavedra, Eric A Miska, Allison L Abbott, Nelson C Lau, David P Bartel, Victor Ambros, Bob Horvitz

CHARACTERIZATION OF THE SYNTHETIC MULTIVULVA SUPPRESSOR GENE isw-1, A HOMOLOG OF THE DROSOPHILA CHROMATIN-REMODELING ATPASE ISWI
Erik Andersen, Xiaowei Lu, Scott Clark, Bob Horvitz

met-1 AND met-2, TWO PUTATIVE HISTONE METHYLTRANSFERASES, MAY ACT AS SYNTHETIC MULTIVULVA GENES
Erik Andersen, Bob Horvitz

A GENETIC SCREEN FOR NEW GENES INVOLVED IN AGING
Ala Berdichevsky, Leonard Guarente, Bob Horvitz

CHARACTERIZATION OF THE CELL DEATHS CAUSED BY MUTATIONS IN lin-24 AND lin-33
Brendan Galvin, Saechin Kim, Erika Hartwieg, Bob Horvitz

ANALYSIS OF SYNMUV PROTEIN COMPLEXES IN VIVO AND CHARACTERIZATION OF THE CLASS B SYNMUV GENE lin-61
Melissa M Harrison, Xiaowei Lu, Bob Horvitz

GENES INVOLVED IN SEROTONERGIC NEUROTRANSMISSION
Megan Higginbotham, Bob Horvitz

A SCREEN FOR GENES SYNTHETICALLY LETHAL WITH lin-35 Rb
Mike Hurwitz, Bob Horvitz

GENETIC ANALYSIS OF THE PUTATIVE SUP-9/SUP-10/UNC-93 TWO-PORE DOMAIN K+ CHANNEL COMPLEX
Long Ma, Bob Horvitz

FUNCTIONAL ANALYSIS OF THE MICRORNA GENES OF C. ELEGANS
Eric A Miska, Ezequiel Alvarez-Saavedra, Allison L Abbott, Andrew B Hellman, Nelson C Lau, David P Bartel, Victor Ambros, Bob Horvitz

SOME DAUER FORMATION, SOCIAL FEEDING, AND CHEMOTAXIS MUTANTS ARE ABNORMAL IN THE ENHANCED SLOWING RESPONSE
Daniel Omura, Bob Horvitz

MODULATION OF C. ELEGANS EGG-LAYING BEHAVIOR BY THE ENVIRONMENT AND EXPERIENCE
Niels Ringstad, Bob Horvitz

PROGRESS TOWARDS THE CLONING OF lin-38 AND IDENTIFICATION OF NOVEL CLASS A SYNMUV GENES
Adam Saffer, Ewa Davison, Bob Horvitz

THE BarH CLASS HOMEODOMAIN GENE ceh-30 IS DIRECTLY REGULATED BY tra-1 TO SPECIFY THE SEXUALLY DIMORPHIC SURVIVAL OF THE CEM NEURONS
Hillel Schwartz, Bob Horvitz

THE "GREEN PHARYNX" PHENOTYPE OF TRANSGENE MISEXPRESSION YIELDS NEW INSIGHT INTO THE SYNMUV GENES
Hillel Schwartz, Dawn Wendell, Bob Horvitz

GENETIC SCREENS FOR SUPPRESSORS OF THE ceh-30(n3714gf) PHENOTYPE OF INAPPROPRIATE SURVIVAL OF THE MALE-SPECIFIC CEM NEURONS IN HERMAPHRODITES
Johanna Varner, Hillel Schwartz, Bob Horvitz

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14th International C. elegans Conference, June, 2003
University of California, Los Angeles, CA

TYRAMINE MODULATES FORAGING BEHAVIOR AND HEAD MOVEMENTS
Mark J. Alkema, Melissa Hunter-Ensor, Niels Ringstad, Bob Horvitz

FUNCTIONAL ANALYSIS OF THE MICRORNA GENES OF C. ELEGANS
Ezequiel A. Alvarez-Saavedra, Eric A. Miska, Allison L. Abbott, Nelson C. Lau, David P. Bartel, Victor Ambros, Bob Horvitz

CHARACTERIZATION OF THE SYNTHETIC MULTIVULVA SUPPRESSOR ISW-1, THE C. ELEGANS HOMOLOG OF THE CHROMATIN-REMODELING ATPASE ISWI
Erik C. Andersen, Xiaowei Lu, Scott Clark, Bob Horvitz

A GENETIC SCREEN FOR NEW GENES INVOLVED IN AGING
Ala Berdichevsky, Leonard Guarente, Bob Horvitz

TWO MODIFIER SCREENS FOR NEW GENES INVOLVED IN PROGRAMMED CELL DEATH
Brendan D. Galvin, Bob Horvitz

FUNCTIONAL STUDIES OF THE CLASS B SYNMUVS AND CHARACTERIZATION OF THE CLASS B SYNMUV GENE lin-61
Melissa Harrison, Xiaowei Lu, Bob Horvitz

A MOD-5 SUPPRESSION SCREEN FOR GENES INVOLVED IN SEROTONERGIC NEUROTRANSMISSION
Megan A. Higginbotham, Bob Horvitz

A SCREEN FOR GENES SYNTHETICALLY LETHAL WITH lin-35
Mike Hurwitz, Bob Horvitz

MUTANT PHENOTYPES OF THE MICRO RNA GENES OF C. ELEGANS
Eric A. Miska, Ezequiel Alvarez-Saavedra, Allison Abbott, Nelson Lau, David P. Bartel, Victor Ambros, Bob Horvitz

MUTATIONS THAT CAUSE FOOD-DEPRIVED BEHAVIOR IN WELL-FED ANIMALS
Daniel Omura, Bob Horvitz

MODULATION OF C. ELEGANS EGG-LAYING BEHAVIOR BY THE ENVIRONMENT AND EXPERIENCE
Niels Ringstad, Bob Horvitz

THE GREEN PHARYNX PHENOTYPE OF TRANSGENE MISEXPRESSION YIELDS NEW INSIGHT INTO THE SYNMUV GENES
Hillel Schwartz, Dawn Wendell, Bob Horvitz

THE BARH CLASS HOMOEODOMAIN GENE ceh-30 IS DIRECTLY REGULATED BY tra-1 TO SPECIFY THE SEXUALLY DIMORPHIC SURVIVAL OF THE CEM NEURONS
Hillel Schwartz, Bob Horvitz

ced-7 MIGHT BE INVOLVED IN ced-3-INDEPENDENT PROGRAMMED CELL DEATH
Fang Xie, Bob Horvitz

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West Coast C. elegans Meeting, August, 2002
University of California, San Diego, CA

CHARACTERIZATION OF THE CLASS A SYNMUV PROTEINS LIN-56 AND LIN-15A
Ewa M. Davison, John DeModena, Linda S. Huang, Paul W. Sternberg, and Bob Horvitz

MODULATION OF C. ELEGANS EGG-LAYING BEHAVIOR BY THE ENVIRONMENT AND EXPERIENCE
Niels Ringstad and Bob Horvitz

MUTATIONS THAT CAUSE FOOD-DEPRIVED BEHAVIOR IN WELL-FED ANIMAL
Daniel Omura and Bob Horvitz

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East Coast C. elegans Meeting, June, 2002
University of New Hampshire, Durham, NH

A GENETIC PATHWAY FOR THE CONTROL OF THE SEXUALLY DIMORPHIC DEATHS OF CEM NEURONS
Hillel Schwartz and Bob Horvitz

TWO MODIFIER SCREENS FOR NEW GENES INVOLVED IN PROGRAMMED CELL DEATH
Brendan Galvin, Peter Reddien, and Bob Horvitz

A SCREEN FOR ESSENTIAL CELL-DEATH GENES
Anna Heineman and Bob Horvitz

A NEW CLASS OF SYNMUV MUTATIONS IS PREDICTED TO DISRUPT A HISTONE ACETYLTRANSFERASE COMPLEX
Craig Ceol and Bob Horvitz

CHARACTERIZATION OF lin-54 AND OTHER GENES THAT NEGATIVELY REGULATE let-60 Ras SIGNALING DURING VULVAL DEVELOPMENT
Craig Ceol and Bob Horvitz

FUNCTIONAL STUDIES OF THE CLASS B SYNMUVS, GENES REQUIRED FOR NEGATIVE REGULATION OF VULVAL INDUCTION, AND CHARACTERIZATION OF THE CLASS B SYNMUV GENE lin-61
Melissa Harrison, Xiaowei Lu, and Bob Horvitz

IDENTIFICATION AND CHARACTERIZATION OF SYNMUV SUPPRESSORS, INCLUDING A HOMOLOG OF THE CHROMATIN-REMODELING ATPASE ISWI
Erik Andersen, Xiaowei Lu, Scott Clark, and Bob Horvitz

A NOVEL PHENOTYPE OF TRANSGENE MISEXPRESSION YIELDS NEW INSIGHT INTO THE SYNMUV GENES
Hillel Schwartz, Dawn Wendell, and Bob Horvitz

A SCREEN FOR GENES SYNTHETICALLY LETHAL WITH lin-35 Rb
Mike Hurwitz and Bob Horvitz

SQV-4 UDP-GLUCOSE DEHYDROGENASE IS TEMPORALLY AND SPATIALLY REGULATED TO CONTROL C. ELEGANS VULVAL MORPHOGENESIS
Ho-Yon Hwang and Bob Horvitz

THE PUTATIVE REGULATORY SUBUNITS SUP-10 AND SUP-18 REGULATE THE SUP-9 TWO-PORE K+ CHANNEL THROUGH A MECHANISM THAT IS DISTINCT FROM THAT OF THE UNC-93 SUBUNIT
Ignacio Perez de la Cruz and Bob Horvitz

A mod-5 SUPPRESSION SCREEN FOR GENES INVOLVED IN SEROTONERGIC NEUROTRANSMISSION
Megan Higginbotham, Rajesh Ranganathan, and Bob Horvitz

FUNCTIONAL ANALYSIS OF THE MICRORNA GENES OF C. ELEGANS
Ezequiel Alvarez-Saavedra, Eric Miska, Allison Abbott, Nelson C. Lau, David P. Bartel, Victor Ambros, and Bob Horvitz

egl-41, WHICH MAY ACT IN SEX DETERMINATION, IS IDENTICAL TO sel-10, WHICH ENCODES AN F-BOX PROTEIN AND NEGATIVE REGULATOR OF lin-12/Notch
Sibylle Jager, Hillel Schwartz, Bob Horvitz, Barbara Conradt

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European C. elegans Meeting, May, 2002
Paestum, Italy

C. ELEGANS CREB MUTANTS SHOW DEFECTS IN DAUER FORMATION AND IN BEHAVIORS THAT ARE COUPLED TO FOOD SENSATION
Mark Alkema and Bob Horvitz

FUNCTIONAL ANALYSIS OF THE MICRORNA GENES OF C. ELEGANS
Eric Miska, Ezequiel Alvarez-Saavedra, Allison Abbott, Nelson C. Lau, David P. Bartel, Victor Ambros, and Bob Horvitz

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13th International C. elegans Meeting, June, 2001
University of California, Los Angeles, CA

IDENTIFICATION OF TWO GENES THAT CONTROL THE SURVIVAL OF THE MALE-SPECIFIC CEM NEURONS
Hillel Schwartz and Bob Horvitz

TWO NEW CELL-DEATH GENES AND ENGULFMENT CONTRIBUTE TO CELL KILLING
Peter Reddien, Scott Cameron, Michael Huang, and Bob Horvitz

A ced-4 SUPPRESSION SCREEN TO INDENTIFY NEW GENES INVOLVED IN PROGRAMMED CELL DEATH
Brendan Galvin, Scott Cameron, and Bob Horvitz

CED-12, A COMPONENT OF A RHO/RAC GTPASE SIGNALING PATHWAY, REGULATES CYTOSKELEAL REORGANIZATION AND CONTROLS CELL-CORPSE ENGULFMENT AND CELL MIGRATION IN C. ELEGANS
Zheng Zhou, Emmanuelle Caron, Angell Shieh, Erika Hartwieg, Alan Hall, and Bob Horvitz

C. ELEGANS rac GENES CONTROL AXON GUIDANCE, CELL MIGRATION, AND CELL-CORPSE ENGULFMENT
Peter Reddien, Erik Lundquist, Erika Hartwieg, Cori Bargmann, and Bob Horvitz

ORDERING THE SYNMUV CLASS A PROTEINS: LIN-15A MAY BE IMPORTANT FOR THE NUCLEAR EXPRESSION OF LIN-56
Ewa M. Davison and Bob Horvitz

IDENTIFICATION AND CHARACTERIZATION OF lin-35 Rb PATHWAY GENES THAT ANTAGONIZE RAS SIGNALING DURING VULVAL INDUCTION
Craig Ceol and Bob Horvitz

FUNCTIONAL STUDIES OF THE CLASS B SYNMUVS REQUIRED FOR THE NEGATIVE REGULATION OF VULVAL INDUCTION AND CHARACTERIZATION OF A NOVEL CLASS B SYNMUV GENE
Melissa Harrison and Bob Horvitz

ISOLATION AND CHARACTERIZATION OF NEW SYNMUV GENES, INCLUDING lin-61, A CLASS B GENE WITH ROLES IN CELL DIVISION AND MULTIPLE POSTEMBRYONIC DEVELOPMENT PROCESSES
John Doll, Xiaowei Lu, and Bob Horvitz

A PROTEOGLYCAN BIOSYNTHETIC PATHWAY INVOLVED IN C. ELEGANS EMBRYOGENESIS AND VULVAL MORPHOGENESIS AND IN HUMAN AGING DISORDERS
Ho-Yon Hwang and Bob Horvitz

C. ELEGANS MUTANTS IN THE muc-1 GENE PROVIDE A MODEL FOR THE HUMAN LYSOSOMAL STORAGE DISEASE MUCOLIPIDOSIS TYPE IV
Brad Hersh, Erika Hartwieg, and Bob Horvitz

THE C. ELEGANS LISSENCEPHALY (LIS1)-LIKE GENE lis-1 IS REQUIRED FOR EMBRYONIC DEVELOPMENT
Ned Buttner and Bob Horvitz

PAG-3 MAY COUPLE CELL LINEAGE CUES TO TERMINAL DIFFERENTIATION THROUGH HETERODIMERIZATION WITH UNC-3 IN DEVELOPING VA AND VB MOTOR NEURONS
Scott Cameron, Brinda Prasad, Joan B. McDermott, Eric Aamodt, Randall R. Reed, and Bob Horvitz

CHARACTERIZING THE NEURONAL FUNCTION OF THE SUP-9/SUP-10/UNC-93 TWO-PORE K+ CHANNEL COMPLEX
Ignacio Perez de la Cruz and Bob Horvitz

A mod-5 SUPPRESSION SCREEN FOR GENES INVOLVED IN SEROTONERGIC NEUROTRANSMISSION
Megan Higginbotham, Rajesh Ranganathan, Bob Horvitz

FOOD-DEPRIVATION AND MODULATION OF BEHAVIOR: mod-6 AND A SCREEN FOR NEW GENES
Daniel Omura, Rajesh Ranganathan, and Bob Horvitz

adc-1 MUTANTS FORAGE HILE MOVING BACKWARDS
Melissa Hunter-Ensor and Bob Horvitz

A C. ELEGANS CREB PROTEIN MODULATES TGF-BETA SIGNALING
Mark Alkema and Bob Horvitz

GENETIC ANALYSIS OF THE NICTATION BEHAVIOR OF DAUER LARVAE
Eric Miska and Bob Horvitz

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East Coast C. elegans Meeting, June, 2000
Emory University, Atlanta, GA

CED-9 AND EGL-1 REGULATE THE SUBCELLULAR LOCALIZATION OF CED-4
Brad Hersh, Fangli Chen, Barbara Conradt, Zheng Zhou, and Bob Horvitz

A SCREEN FOR MUTANTS DEFECTIVE IN THE SPECIFICATION OF THE PROGRAMMED CELL DEATHS OF THE MALE-SPECIFIC CEM NEURONS
Hillel Schwartz and Bob Horvitz

TWO SCREENS FOR NEW GENES INVOLVED IN PROGRAMMED CELL DEATH
Brendan Galvin, Scott Cameron, and Bob Horvitz

TWO NEW CELL-DEATH GENES AND CELL-CORPSE ENGULFMENT GENES BOTH CONTRIBUTE TO CELL KILLING
Peter Reddien, Scott Cameron, Michael Huang, and Bob Horvitz

THE CELL-CORPSE ENGULFMENT PROTEIN CED-1 IS A TRANSMEMBRANE RECEPTOR THAT RECOGNIZES CELL CORPSES
Zheng Zhou and Bob Horvitz

THE CED-2 CrkII, CED-5 DOCK180, CED-10 Rac PATHWAY CONTROLS CELL-CORPSE ENGULFMENT AND CELL MIGRATION, AND CED-10 FUNCTIONS REDUNDANTLY WITH THE MIG-2 RHO-TYPE GTPASE TO CONTROL AXON GUIDANCE
Peter Reddien, Erik Lundquist, Erika Hartwieg, Cori bargmann, and Bob Horvitz

n3194, IDENTIFIED IN A SCREEN FOR SUPPRESSORS OF ced-9 (n1950), MAY BE REQUIRED FOR CELL VIABILITY
Brad Hersh, Erika Hartwieg, and Bob Horvitz

pag-3 AND unc-3 INTERACT TO DETERMINE NEURAL FATES IN THE VENTRAL CORD, AND THEIR MAMMALIAN COUNTERPARTS MAY SIMILARLY INTERACT DURING BLOOD CELL DEVELOPMENT
Scott Cameron, Brinda Prasad, Joan B. McDermott, Eric Aamodt, Randall R. Reed, and Bob Horvitz

IDENTIFICATION AND CHARACTERIZATION OF GENES THAT ACT WITH lin-35 Rb TO NEGATIVELY REGULATE VULVAL INDUCTION
Craig Ceol, Frank Stegmeier, Melissa Harrison, and Bob Horvitz

CHARACTERIZATION OF NEW GENES REQUIRED FOR THE NEGATIVE REGULATION OF VULVAL INDUCTION, INCLUDING THE NEW CLASS B SYNMUV GENE lin-61
John Doll, Xiaowei Lu, and Bob Horvitz

CHARACTERIZATION OF THE CLASS A SYNMUV MULTIVULVA GENES lin-8 and lin-56
Ewa M. Davison and Bob Horvitz

DEFECTS IN GAG BIOSYNTHESIS ARE RESPONSIBLE FOR THE C. ELEGANS Sqv PHENOTYPE AND HUMAN EHLERS-DANLOS SYNDROME
Ho-Yon Hwang, Tory Herman, Patricia Berninsone, Carlos Hirschberg, and Bob Horvitz

THE SURVIVIN-LIKE C. ELEGANS PROTEIN BIR-1 ACTS WITH THE AURORA-LIKE KINASE AIR-2 TO MEDIATE CHROMOSOME BEHAVIOR AND SPINDLE MIDZONE FORMATION
Liz Speliotes, Anthony Uren, David Vaux, and Bob Horvitz

CHARACTERIZATION OF sup-11 AND sup-18, TWO REGULATORS OF THE SUP-9/SUP-10/UNC-93 TWO-PORE POTASSIUM CHANNEL COMPLEX
Ignacio Perez de la Cruz and Bob Horvitz

mod-1 AND mod-5 CONTROL SEROTONERGIC NEUROTRANSMISSION AND EXPERIENCE-DEPENDENT MODULATION OF LOCOMOTORY BEHAVIOR
Rajesh Ranganathan, Megan Higginbotham, Beth Sawin, and Bob Horvitz

FOOD DEPRIVATION AND MODULATION OF LOCOMOTORY BEHAVIOR: mod-6 AND A SCREEN FOR NEW GENES
Daniel Omura, Rajesh Ranganathan, and Bob Horvitz

CRB-1 MAY FUNCTION IN SYNAPTIC TRANSMISSION AND DAUER FORMATION
Mark Alkema and Bob Horvitz

HISTAMINE: A POSSIBLE NEUROMODULATOR IN C. ELEGANS
Melissa Hunter-Ensor and Bob Horvitz

A PROTOCOL FOR THE USE OF ELECTRON MICROSCOPY IN STUDIES OF AXONAL PATHFINDING
Erika Hartwieg, Peter Reddien, and Bob Horvitz

THE C. ELEGANS LISSENCEPHALY (LIS1)-LIKE GENE lis-1 IS REQUIRED FOR EMBRYONIC DEVELOPMENT
Ned Buttner and Bob Horvitz

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12th International C. elegans Meeting, June, 1999
University of Wisconsin, Madison, WI

THE TRA-1 SEX DETERMINATION PROTEIN REGULATES SEXUALLY DIMORPHIC PROGRAMMED CELL DEATH BY TRANSCRIPTIONALLY REPRESSING THE egl-1 CELL-DEATH ACTIVATOR GENE
Barbara Conradt and Bob Horvitz

CED-9 AND EGL-1 REGULATE THE SUBCELLULAR LOCALIZATION OF CED-4
Brad Hersh, Fangli Chen, Barbara Conradt, Zheng Zhou, and Bob Horvitz

A SCREEN FOR MUTATIONS THAT AFFECT THE LOCALIZATION OF CED-4
Daniel Omura, Brad Hersh, Fangli Chen, and Bob Horvitz

GENETIC AND MOLECULAR ANALYSES OF ced-8, WHICH CONTROLS THE TIME OF APPEARANCE OF CELL CORPSES
Brendan Galvin and Bob Horvitz

THE CELL-CORPSE ENGULFMENT GENE ced-1 ENCODES A TRANSMEMBRANE RECEPTOR THAT MAY ACT TO RECOGNIZE DYING CELLS
Zheng Zhou and Bob Horvitz

A CED-2/Crk-II, CED-5/DOCK180, CED-10/Rac PATHWAY CONTROLS CELL-CORPSE ENGULFMENT AND CELL MIGRATION
Peter Reddien and Bob Horvitz

THE ENGULFMENT OF DYING CELLS CONTRIBUTES TO THE KILLING PROCESS OF PROGRAMMED CELL DEATH
Peter Reddien, Scott Cameron, and Bob Horvitz

ANALYSIS OF DOWNSTREAM EVENTS IN THE PATHWAY FOR PROGRAMMED CELL DEATH
Gillian Stanfield, Yi-Chun Wu, Erika Hartwieg, and Bob Horvitz

A SCREEN FOR MUTATIONS THAT AFFECT PROGRAMMED CELL DEATH IN THE VENTRAL CORD
Scott Cameron, Nancy Tsung, and Bob Horvitz

A SCREEN FOR MUTANTS DEFECTIVE IN THE SPECIFICATION OF PROGRAMMED CELL DEATH IN THE POSTDEIRID LINEAGE
Hillel Schwartz and Bob Horvitz

n3194, IDENTIFIED IN A SCREEN FOR SUPRESSORS OF ced-9 (n1950), MAY DEFINE AN ION CHANNEL REQUIRED FOR CELL VIABILITY
Brad Hersh, Erika Hartwieg, and Bob Horvitz

THE INHIBITOR-OF-APOPTOSIS (IAP)-LIKE PROTEIN BIR-1 IS REQUIRED FOR CYTOKINESIS
E. K. Speliotes, A. Uren, D. Vaux, and H. R. Horvitz

pag-3 MAY SPECIFY BOTH NEUROBLAST CELL FATE AND TERMINAL FATES DURING DEVELOPMENT OF THE VENTRAL CORD
Scott Cameron, Joan B. McDermott, Eric Aamodt, and Bob Horvitz

lin-55 DP AND AN E2F-LIKE GENE ACT IN THE lin-35 Rb PATHWAY TO ANTAGONIZE let-60 Ras SIGNALING DURING VULVAL INDUCTION
Craig Ceol and Bob Horvitz

CLONING AND CHARACTERIZATION OF THE CLASS A SYNTHETIC MULTIVULVA GENES
Ewa M. Davison and Bob Horvitz

ISOLATION AND CHARACTERIZATION OF NEW CLASS A SYNTHETIC MULTIVULVA GENES
John Doll, Ewa Davison, and Bob Horvitz

NUCLEOTIDE-SUGAR BIOSYNTHESIS AND GLYCOSYLATION ARE INVOLVED IN VULVAL MORPHOGENESIS
Ho-Yon Hwang and Bob Horvitz

SUP-9 AND SUP-18 MAY BE COMPONENTS OF A K+ CHANNEL INVOLVED IN THE REGULATION OF MUSCLE CONTRACTION
Ignacio Perez de la Cruz, Stephen C. Cannon, and Bob Horvitz

AN IONOTROPHIC SEROTONIN RECEPTOR AND A SEROTONIN REUPTAKE TRANSPORTER ARE INVOLVED IN EXPERIENCE-DEPENDENT MODULATION OF BEHAVIOR
Rajesh Ranganathan, Stephen C. Cannon, and Bob Horvitz

NEUROMODULATION IN C. ELEGANS AND unc-34 SUPPRESSORS
Melissa Hunter-Ensor and Bob Horvitz

DETERMINING THE ROLES OF OCTOPAMINE AND CRB IN WORM BEHAVIOR
Mark Alkema and Bob Horvitz

STUDYING HUMAN DISEASE GENES IN C. ELEGANS
Ned Buttner and Bob Horvitz

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The Horvitz Lab