2013

• Nuria Oliva †‡, Sagi Shitreet †§, Eytan Abraham †, Butch Stanley #, Elazer R. Edelman *†, and Natalie Artzi *†Natural Tissue Microenvironmental Conditions Modulate Adhesive Material Performance Langmuir, 2012, 28 (43), pp 15402–15409 DOI: 10.1021/la303155p Publication Date (Web): October 8, 2012 [e-pub]

2012

• Nugent HM, Ng YS, White D, Groothius A, Kanner G, Edelman ER. Ultrasound-guided percutaneous delivery of tissue-engineered endothelial cells to the adventitia of stented arteries controls the response to vascular injury in a porcine model. J Vasc Surg. 2012 Oct;56(4):1078-88. doi: 10.1016/j.jvs.2012.03.002. 2012 Jul 15 [e-pub]

• Carlyle WC, McClain JB, Tzafriri AR, Bailey L, Zani BG, Markham PM, Stanley JR, Edelman ER. Enhanced Drug Delivery Capabilities from Stents Coated with Absorbable Polymer and Crystalline Drug. Journal of controlled release : official journal of the Controlled Release Society. 2012 Jul 13. [e-pub]

• Indolfi L, Baker AB, Edelman ER. The role of scaffold microarchitecture in engineering endothelial cell immunomodulation. Biomaterials. 2012 Jul 12. [PDF]

• Nugent HM, Ng YS, White D, Groothius A, Kanner G, Edelman ER. Ultrasound-guided, percutaneous delivery of tissue-engineered endothelial cells to the adventitia of stented arteries controls the response to vascular injury in a porcine model. Journal of Vascular Surgery. 2012 Jul 13. [e-pub]

• Tzafriri AR, Groothuis A, Price GS, Edelman ER. Stent elution rate determines drug deposition and receptor-mediated effects. Journal of controlled release : official journal of the Controlled Release Society. 2012 May 26;161(3):918-926. [PDF]

• Baker AB, Gibson WJ, Kolachalama VB, Golomb M, Indolfi L, Spruell C, Zcharia E, Vlodavsky I, Edelman ER. Heparanase regulates thrombosis in vascular injury and stent-induced flow disturbance. Journal of the American College of Cardiology. 2012 Apr 24;59(17):1551-60. 22516446 [PDF]

• Martorell J, Santomá P, Molins JJ, García-Granada AA, Bea JA, Edelman ER, Balcells M. Engineered arterial models to correlate blood flow. Annals of The New York Academy of Sciences. 2012 Apr;1254:51-6. [PDF]

• Edelman ER, LaMarco K. Clinician-investigators as translational bioscientists: shaping a seamless identity. Science Translational Medicine. 2012;4(135):135fs14 [PDF]

• Shazly T, Kolachalama VB, Ferdous J, Oberhauser JP, Hossainy S, Edelman ER. Assessment of material by-product fate from bioresorbable vascular scaffolds. Annals of biomedical engineering. 2012;40(4):955-65. [PDF]

• Jang E, Albadawi H, Watkins MT, Edelman ER, Baker AB. Syndecan-4 proteoliposomes enhance fibroblast growth factor-2 (FGF-2)-induced proliferation, migration, and neovascularization of ischemic muscle. Proceedings of the National Academy of Sciences of the United States of America. 2012;109(5):1679-84. [PDF]

• Aronson D, Edelman ER. Role of CABG in the management of obstructive coronary arterial disease in patients with diabetes mellitus. Current opinion in pharmacology. [PDF]

2011

• Franses JW, Edelman ER. The evolution of endothelial regulatory paradigms in cancer biology and vascular repair. Cancer research. 2011;71(24):7339-44. [PDF]

• Balcells M, Edelman ER. Models of human vascular disease: is there an animal of la mancha?. Revista espanola de cardiologia. 2011;64(9):739-42. [PDF]

• Edelman, ER, FitzGerald, GA. A rattle bag of science and the art of translation. Science Translational Medicine 2011 Oct; (3)104:104ed3. [PDF]

• Lovich M, Wei A, Wu P, Maslov M, Edelman ER. Local epicardial inotropic drug delivery allows targeted pharmacologic intervention with preservation of myocardial loading conditions. Journal of Pharmaecutical Sciences 2011 Nov;100(11):4993-5006. [PDF]

• Chitalia V, Murikipudi S, Indolfi L, Rabadi L, Valdez R, Franses J, Edelman ER. Matrix-embedded endothelial cells are protected from the uremic milieu. Nephrology Dialysis Transplantation 2011 July; 0:1-8. [PDF]

• Artzi N, Oliva N, Puron C, Shitreet S, Artzi S, Bon Ramos A, Groothuis A, Sahagian G, Edelman ER. In vivo and in vitro tracking of erosion in biodegradable materials using non-invasive fluorescence imaging. Nature Materials 2011 Sep; 10(9):704-709. [PDF]

• Kolandaivelu K, Swaminathan R, Gibson W, Kolachalama V, Nguyen-Ehrenreich KL, Giddings V, Coleman L, Wong G, Edelman ER. Stent thrombogenicity early in high-rish interventional settings is driven by stent design and deployment and proteced by polymer-drug coatings. Circulation 2011 Apr; 123(13): 1400-1409. [PDF]

• Schubert S, Benarroch A, Monter-Solans J, Edelman ER. Primary monocytes regulate endothelial cell survival through secretion of angiopoietin-1 and activation of endothelial Tie2. Arteriosclerosis Thrombosis and Vascular Biology 2011 Apr; 31(4): 870-875. [PDF]

• Chatzizisis Y, Baker A, Sukhova G, Koskinas K, Papafaklis M, Beigel R, Jonas M, Coskun A, Stone B, Maynard C, Shi GP, Libby P, Feldman C, Edelman ER, Stone P. Augmented expression and activity of extracellular matrix-degrading enzymes in regions of low endothelial shear stress co-localize with coronary atheromata with thin fibrous caps in pigs. Circulation 2011 Feb; 123(6): 621-630.[PDF]

• Franses JW, Baker AB, Chitalia VC, Edelman ER. Stromal endothelial cells directly influence cancer progression. Science Translational Medicine 2011 Jan; 66(3):66ra5. [PDF] [COVER]

• Artzi N, Zeiger A, Boehning F, Bon Ramos A, Van Vliet K, Edelman ER. Tuning adhesion failure strength for tissue-specific applications. Acta Biomaterialia 2011 Jan; 7(1): 67-74. [PDF]

2010

• Baker A, Chatzizisis Y, Beigel R, Jonas M, Stone B, Coskun A, Maynard C, Rogers C, Koskinas K, Feldman C, Stone P, Edelman ER. Regulation of heparanase expression in coronary artery disease in diabetic hyperlipidemic swine. Atherosclerosis 2010 Dec; 213(2):436-442. [PDF]

• Shazly T, Baker A, Naber J, Bon A, Van Vliet K, Edelman ER. Augumentation of postswelling surgical sealant potential of adhesive hydrogels. Journal of Biomedical Materials Resources A 2010 Sept; 95(4):1159-69. [PDF]

• Balcells M, Martorell J, Olive C, Santacana M, Chitalia V, Cardoso A, Edelman ER. Smooth muscle cells orchestrate the endothelial cell response to flow and injury. Circulation 2010 May; 121(20): 2192-9. [PDF]

• Zani BG and Edelman ER. Cellular bridges: routes for intercellular communication and cell migration. Communicative and Integrative Biology 3:3, 1-6; May/June 2010. [PDF]

• Koskinas K, Feldman C, Chatzizisis Y, Coskun A, Jonas M, Maynard C, Baker A, Papafaklis M, Edelman ER, Stone P. Natural History of Experimental Coronary Atherosclerosis and Vascular Remodeling in Relation to Endothelial Shear Stress. A Serial, In Vivo Intravascular Ultrasound Study. Circulation 2010 May; 121(19):2092-101.[PDF]

• Brown L, Edelman ER. Optimal control of blood glucose: the diabetic patient or the machine. www. Science Translation Medicine.org 2010 Apr;27(2): 27ps18. [PDF]

• Methe H, Nanasato M, Spognardi A, Groothuis A, Edelman ER. T-helper 2 cells are essential for modulation of vascular repair by allogeneic endothelial cells. Journal of Heart and Lung Transplantation 2010 Apr; 29(4):479-486 [PDF]

• Aronson D, Edelman ER. Revascularization for coronary artery disease in diabetes mellitus: Angioplasty, stents and coronary artery bypass grafting. Reviews in Endocrine and Metabolic Disorders 2010 Mar; 11(1): 75-86.[PDF]

• Tzafriri A, Vukmirovic N, Kolachalama V, Astafieve I, Edelman ER. Lesion complexity determines arterial drug distribution after local drug delivery. Journal of Controlled Release 2010 Mar;142(3): 332-338.[PDF]

• Schubert SY, Benarroch A, Monter-Solans J, Edelman ER. Monocyte activation state regulates monocyte-induced endothelial proliferation through Met signaling. Blood 2010 Apr;115(16):3407-3412. [PDF]

• Zani BG, Indolfi L, Edelman ER. Tubular bridges for bronchial epithelial cell migration and communication. PloS ONE 2010 Jan; 5(1): e8930.[PDF]

• Kolachalama VB, Levine EG, Edelman ER. Luminal flow amplifies stent-based drug deposition in arterial bifurcations. PloS ONE 2009 Dec; 4(12): e8105.[PDF]

• Nugent HM, Ng YS, White D, Groothius A, Kanner G, Edelman ER. Delivery Site of Perivascular Endothelial Cell Matrices Determines Control of Stenosis in a Porcine Femoral Stent Model. Journal of Vascular Intervention in Radiology 2009 Dec; 20(12):1617-24.[PDF]

• Koskinas, KC, Chatzizisis YS, Baker AB, Edelman ER, Stone PH, Feldman CL. The role of low endothelial shear stress in the conversion of atherosclerotic lesions from stable to unstable plaque. Current Opinion in Cardiology 2009 Oct; 24(6):580-90.[PDF]

• Artzi N, Shazly T, Crespo C, Bon Ramos A, Chenault K, Edelman ER. Characterization of star adhesive sealant based on PEG:dextran hydrogels. Macromolecular Bioscience 2009 Aug;9(8):754-65.[PDF]

• Artzi N*, Shazly T*, Baker A, Bon A, Edelman ER. Aldehyde-Amine Chemistry Enables Modulated Biosealants with Tissue-Specific Adhesion. Advanced Materials 2009; 21:3399-3403.*Indicates equal author contribution.[PDF]

• Mobine H, Baker A, Wang L, Wakimoto H, Jacobsen K, Seidman C, Seidman J, Edelman ER. Pheochromocytoma-Induced Cardiomyopathy is Modulated by the Synergistic Effects of Cell-Secreted Factors. Circ Heart Fail 2009:1-16. [PDF]

• Wu PI, Minisini S, Edelman ER. Intramuscular drug transport under mechanical loading: resonance between tissue function and uptake. J Control Release 2009; 136(2): 99-109.[PDF]

• Morss Clyne A, Edelman ER. Vascular growth factor binding kinetics to the endothelial cell basement membrane, with a kinetics-based correction for substrate binding. Cytotechnology 2009 Jul; 60(1): 33-44.[PDF]

• Mobine H, Engelmayr G, Moussazadeh N, Anwar T, Freed L, Edelman ER. Encapsulated pheochromocytoma cells secrete potent non-catecholamine factors. Tissue Engineering Part A 2009 Jul;15(7):1719-28.[PDF]

• Hess S, Methe H, Kim JO, Edelman ER. NF-kappaB activity in endothelial cells is modulated by cell substratum interactions and influences chemokine-mediated adhesion of natural killer. Cell Transplantation 2009 18(3): 261-73.[PDF]

• Alexander I, Edelman ER, Methe H. Function and mode of regulation of endothelial major histocompatibility complex class II. Cell Transplantation 2009; 18(3):255-259.[PDF]

• Tzafriri AR, Levin AD, Edelman ER. Diffusion-limited binding explains binary dose response for local arterial and tumor drug delivery. Cell Proliferation 2009 42(3): 348-363. [PDF]

• Le KN, Hwang CW, Tzafriri A, Lovich MA, Hayward A, Edelman ER. Vascular regeneration by local growth factor release is self-limited by microvascular clearance. Circulation 2009;119(22):2928-2935. [PDF]

• Maron B, Kolandaivelu K, Rhee D, Bukhman A, Edelman ER. Echocardiographic capture of right ventricular wall rupture during inferior wall acute myocardial infarction. American Journal of Cardiology 2009 May;103(10):1478-1480. [PDF]

• Chatzizisis YS, Jonas M, Beigel R, Coskun A, Baker AB, Stone BV, Maynard C, Gerrity RG, Daley W, Edelman ER, Feldman CL, Stone PH. Attenuation of inflammation and expansive remodeling by Valsartan alone or in combination with Simvastatin in high-risk coronary atherosclerotic plaques. Atherosclerosis 2009; 203:387-394. [PDF]

• Baker AB, Groothuis A, Jonas M, Ettenson DS, Shazly T, Zcharia E, Vlodavsky I, Seifert P, Edelman ER. Heparanase alters arterial structure, mechanics, and repair following endovascular stenting in mice. Circulation Research 2009 Feb;104(3):380-387.[PDF]

• Kolachalama VB, Tzafriri AR, Arifin DY, Edelman ER. Luminal flow patterns dictate arterial drug deposition in stent-based delivery. J Control Release 2009 Jan; 133(1):24-30. [PDF] [COVER]

2008

• Shazly TM, Artzi N, Boehning F, Edelman ER. Viscoelastic adhesive mechanics of aldehyde-mediated soft tissue sealants. Biomaterials 2008 Dec; 29(35): 4584-4591. [PDF]

• Balakrishnan B, Dooley J, Kopia G, Edelman ER. Thrombus causes fluctuations in arterial drug delivery from intravascular stents. J Control Release 2008 Nov; 131(3):173-180. [PDF]

• Danenberg H, Grad E, Swaminathan RV, Chen Z, Seifert P, Szalai AJ, Lotan C, Simon DI, Edelman ER. Neointimal formation is reduced after arterial injury in human crp transgenic mice. Atherosclerosis 2008 Nov; 201(1):85-91.[PDF]

• Wu P, Edelman ER. Structural biomechanics modulate intramuscular distribution of locally delivered drugs. J Biomech 2008 41(13):2884-2891.[PDF]

• Clyne-Morss A, Zhu H, Edelman ER. Elevated fibroblast growth factor-2 increases tumor necrosis factor-α induced endothelial cell death in high glucose. J Cell Physiol 2008 Oct; 217(1): 86-92. [PDF]

• Baker A, Ettenson D, Jonas M, Nugent M, Iozzo R, Edelman ER. Endothelial cells provide feedback control for vascular remodeling through mechanosensitive autocrine TGF2-beta signaling pathway. Circ Res 2008 Aug;103(3);289-297. [PDF]

• Mi LY, Ettenson D, Edelman ER. Phospholipase C-delta extends intercellular signalling range and responses to injury-released growth factors in non-excitable cells. Cell Prolif 2008 Aug;41(4):671-690. [PDF]

• Epstein H, Grad E, Golomb M, Koroukhov N, Edelman ER, Golomb G, Danenberg H. Innate immunity has a dual effect on vascular healing: Suppression and aggravation of neointimal formation and remodeling post-endotoxin challenge. Atherosclerosis 2008 Jul; 199(1):41-46. [PDF]

• Balcells M, Wallins J, Edelman ER. Amyloid beta toxicity dependent upon endothelial cell state. Neuroscience Letters 2008 Aug; 441(3):319-322.[PDF]

• Zani BG, Kojima K, Vacanti CA, and Edelman ER. Tissue engineered endothelial and epithelial implants differentially and synergistically regulate airway repair. Proc Natl Acad Sci U S A. 2008 May 13; 105(19): 7046-7051. Epub 2008 May 5. [PDF][Supplement]

• Methe H, Hess S, Edelman ER. The effect of three-dimensional matrix-embeding of endothelial cells on the humoral and cellular immune response. Seminars in Immunology 2008 Apr; 20(2):117-122. [PDF]

• Chatzizisis YS, Jonas M, Coskun AU, Beigel R, Stone BV, Maynard C, Gerrity RG, Daley W, Rogers C, Edelman ER, Feldman CL, Stone PH. Prediction of the localization of high-risk coronary atherosclerotic plaques on the basis of low endothelial shear stress. An intravascular ultrasound and histopathology natural history study. Circulation 2008 Feb;117:993-1002. [PDF]

• Schubert SY, Benarroch A, Ostvang J, Edelman ER. Regulation of endothelial cell proliferation by primary monocytes. Arterioscler Thromb Vasc Biol 2008 Jan; 28(1): 97-104. [PDF]

• Schwartz RS, Edelman ER, Virmani R, Carter A, Granada JF, Kaluza GL, Chronos N, Robinson KA, Waksman R, Weinberger J, Wilson GJ, Wilensky RL. Drug-Eluting Stents in Preclinical Studies: Updated Consensus Recommendations for Preclinical Evaluation. Circ Cardiovasc Intervent 2008; 1:143-153. [PDF]

• Balakrishnan B, Dooley J, Kopia G, Edelman ER. Intravascular drug release kinetics dictate arterial drug deposition, retention, and distribution. J Control Release 2007; 123(2): 100-108.[PDF]

• Chatzizisis YS, Coskun AU, Jonas M, Edelman ER, Stone PH, Feldman CL. Risk stratification of individual coronary lesions using local endothelial shear stress: a new paradigm for managing coronary artery disease. Curr Opin Cardiol 2007; 22(6):552-564. [PDF]

• Methe H, Hess S, Edelman ER. Endothelial immunogenicity -- A matter of matrix microarchitecture. Thromb Haemost 2007; 98(2):278-82. [PDF]

• Nugent HM, Sjin RT, White D, Milton LG, Manson RJ, Lawson JH, Edelman ER. Adventitial endothelial implants reduce matrix metalloproteinase-2 expression and increase luminal diameter in porcine arteriovenous grafts. J Vasc Surg 2007 Sept; 46(3):548-556.[PDF]

• Grad E, Golomb M, Mor Yosef I, Koroukhov N, Lotan C, Edelman ER, Danenberg HD. Transgenic expression of human C-reactive protein suppresses endothelial nitric oxide synthase expression and bioactivity folllowing vascular injury. Am J Physiol Heart Circ Physiol 2007 Jul; 293(1): H489-95. [PDF]

• Chatzizisis YS, Coskun AU, Jonas M, Edelman ER, Feldman CL, Stone PH. Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: Molecular, cellular and vascular behavior. J Am Coll Cardiol 2007 Jun 26; 49(25): 2379-2393. [PDF]

• Methe H, Hess S, Edelman ER. Endothelial cell-matrix interactions determine maturation of dendritic cells. Eur J Immunol 2007 Jun 11; 37(7):1773-1784.[PDF]

• Morss AS, Edelman ER. Glucose modulates basement membrane fibroblast growth factor-2 via alternations in endothelial cell permeability. J Biol Chem 2007 May;282(19):14635-14644. [PDF]

• Methe H. Balcells M, Alegret MD, Santacana M, Molins B, Hamik A, Jain M, Edelman ER. Vascular bed origin dictates flow pattern regulation of endothelial adhesion molecule expression. Am J Physiol Heart Circ Physiol 2007 May; 292(5):H2167-2175. [PDF]

• Tzafriri AR, Edelman ER. Quasi-steady state kinetics at enzyme and substrate concentrations in excess of the Michaelis-Menten contstant. J Theor Biol 2007 Apr; 245(4): 737-48. [PDF]

• Tzafriri AR, Edelman ER. Endosomal receptor kinetics determine the stability of intracellular growth factor signaling complexes. Biochem J 2007, Mar 15;402(3):537-549. [PDF]

• Hamik A, Lin Z, Kumar A, Balcells M, Sinha S, Katz J, Feinberg M, Gerzsten R, Edelman ER, Jain M. Kruppel-like factor 4 regulates endothelial inflammation. J Biol Chem 2007 May, 28(18):13769-79. [PDF]

• Thomas A, Edelman ER, Stultz CM. Collagen fragments modulate innate immunity. Exp Biol Med 2007 Mar; 232(3):406-411. [PDF]

• Danenberg HD, Kantak N, Grad E, Swaminathan RV, Lotan C, Edelman ER. C-reactive protein promotes monocyte-platelet aggregation: an additional link to the inflammatory-thrombotic intricacy. Eur J Haematol 2007 Mar;78(3):246-252. [PDF]

• Methe H, Groothuis A, Sayegh MH, Edelman ER. Matrix adherence of endothelial cells attenuates immune reactivity: induction of hyporesponsiveness in allo- and xenogeneic models. Faseb J 2007 Jan; 21(7):1515-26. [PDF]

• Methe H, Edelman ER. Tissue engineering of endothelial cells and the immune response. Transplant Proc 2006 Dec.; 38(10):3293-3299.[PDF]

• Methe, H, Edelman ER. Cell-matrix contact prevents recognition and damage of endothelial cells in states of heightened immunity. Circulation 2006 July 4; 114:I-233-I-238. [PDF]

• Richter Y, Edelman, ER. Cardiology Is Flow. Circulation 2006 June 13;113:2679-2682. [PDF]

• Rogers C, Edelman ER. Pushing Drug-Eluting Stents Into Uncharted Territory. Simpler Than You Think--More Complex Than You Imagine. Circulation 2006 May 16; 113:2262-2265.[PDF]

• Costa LF, Balcells M, Edelman ER, Nadler LM, Cardoso AA. Proangiogenic stimulation of bone marrow endothelium engages mTOR and is inhibited by simultaneous blockage of mTOR and NF-(kappa)B. Blood 2006 107(1): 285-292. [PDF]

• Levin AD, Jonas M, Hwang CW, Edelman ER. Local and systematic drug competition in drug-eluting stent tissue deposition properties. J Control Release 2005 Aug 15;109:236-243.[PDF]

• Methe H, Nugent HM, Groothuis A, Seifert P, Sayegh MH, Edelman, ER. Matrix Embedding Alters the Immune Response Against Endothelial Cells In Vitro and In Vivo. Circulation 2005 Aug 30;112:189-195. [PDF]

• M Jonas M, Edelman ER, Groothuis A, Baker AB, Seifert P, Rogers C. Vascular neointimal formation and signaling pathway activation in response to stent injury in insulin-resistant and diabetic animals. Circ Res 2005 Sep 30;97(7):725-33. Epub 2005 Aug 25 [PDF]

• Methe H, Brunner S, Wiegand D, Nabauer M, Koglin J, Edelman ER. Enhanced T-Helper-1 Lymphocyte Activation Patterns in Acute Coronary Syndromes. J Am Coll Cardiol 2005 Jun 21;45(12):1939-1945. [PDF]

• Balakrishnan B, Tzafriri AR, Seifert P, Groothuis A, Rogers C, Edelman ER. Strut position, blood flow, and drug deposition: implications for single and overlapping drug-eluting stents. Circulation 2005 Jun 7;111(22):2958-65. [PDF]

• Hwang CW, Levin AD, Jonas M, Li PH, Edelman ER. Thrombosis modulates arterial drug distribution for drug-eluting stents. Circulation 2005 Apr 5;111(13):1619-26. [PDF]

• Tzafriri AR , Edelman ER. On the validity of the quasi-steady state approximation of bimolecular reactions in solution. J Theor Biol 2005 Apr 7;233(2):343-350. [PDF]

• Balcells M, Fernandez MS, Vazquez M, Edelman ER. Cells in Fluidic Environments are Sensitive to Flow Frequency. J Cell Physiol 2005 Feb 7; 204: 329-335. [PDF]

• Schwartz RS, Edelman ER, Carter A, Chronos NA, Rogers C, Robinson KA, Waksman R, Machan L,Weinberger J, Wilensky RL, Goode JL, Hottenstein OD, Zuckerman BD, Virmani R. Preclinical evaluation of drug-eluting stents for peripheral applications: recommendations from an expert consensus group. Circulation 2004 Oct 19;110(16):2498-505. [PDF]

• Kolandaivelu K, Edelman ER. Environmental influences on endovascular stent platelet reactivity: An in vitro comparison of stainless steel and gold surfaces. Journal of Biomedical Materials Research 2004 Aug 1;70A(2):186-93. [PDF]

• Levin AD, Vukmirovic N, Hwang CW, Edelman ER. Specific binding to intracellular proteins determines arterial transport properties for rapamycin and paclitaxel. Proceedings of the National Academy of Sciences USA. 2004 Jun 22;101(25):9463-7. [PDF]

• Richter Y, Groothuis A, Seifert P, Edelman ER. Dynamic flow alterations dictate leukocyte adhesion andresponse to endovascular interventions. Journal of Clinical Investigations. 2004 Jun;113(11):1607-14. [PDF] [COVER]

• Tzafriri AR, Wu D, Edelman ER. Analysis of compartmental models of ligand-induced endocytosis . Journal of Theoretical Biology. 2004 Jun 21; 229: 127-138. [PDF]

• Sapp JL, Cooper JM, Soejima K, Sorrell T, Lopera G, Satti SD, Koplan BA, Epstein LM, Edelman E, Rogers C, Stevenson WG. Deep Myocardial Ablation Lesions Can Be Created with a Retractable Needle-Tipped Catheter. Pacing Clin Electrophysiol. 2004 May;27(5):594-599. [PDF]

• Rogers C, Huynh R, Seifert PA, Chevalier B, Schofer J, Edelman ER, Toegel G, Kuchela A, Woupio A, Kuntz RE, Macon ND. Embolic protection with filtering or occlusion balloons during saphenous vein graft stenting retrieves identical volumes and sizes of particulate debris. Circulation. 2004 Apr13;109(14):1735-40. [PDF]

• Wu D, Edelman ER. Resonance Energy Transfer for Assessing the Molecular Integrity of Proteins for Local Delivery. Biotechnology and Bioengineering. 2004 Feb 20; 85(4): 406-412. [PDF]

• Tzafriri AR, Edelman ER. The Total Quasi-Steady State Approximation is Valid for Reversible Enzyme Kinetics . Journal of Theoretical Biology. 2004 Feb 7; 226: 301-311. [PDF]

• Danenberg HD, Golomb G, Groothuis A, Gao J, Epstein H, Swaminathan RV, Seifert P, Edelman ER. Liposomal Alendronate Inhibits Systemic Innate Immunity and Reduces In-Stent NeointimalHyperplasia in Rabbits. Circulation. 2003 Dec 2; 108(22):2798-2804. [PDF] [COVER]

• Janicki C, Hwang CW, Edelman ER. Dose model for stent-based delivery of a radioactive compound for the treatment of restenosis in coronary arteries. Medical Physics. 2003 Oct; 30(10): 2622-2628. [PDF]

• Stultz CM, Edelman ER. A structural model that explains the effects of hyperglycemia on collagenolysis. Biophysical Journal. 2003 Oct; 85(4):2198-2204. [PDF]

• Danenberg HD, Szalai AJ, Swaminathan RV, Peng L, Chen Z, Seifert P, Fay WP, Simon DI, Edelman ER. Increased thrombosis after arterial injury in human C-reactive protein-transgenic mice. Circulation. 2003 Aug 5;108(5):512-5. [PDF]

• Welt FG, Tso C, Edelman ER, Kjelsberg MA, Paolini JF, Seifert P, Rogers C. Leukocyte recruitment and expression of chemokines following different forms of vascular injury. Vascular Medicine. 2003;8(1):17. [PDF]

• Edelman ER, Danenberg HD. Rapamycin for cardiac transplant rejection and vasculopathy: one stone, two birds? Circulation. 2003 Jul 8;108(1):6-8. [PDF]

• Nugent HM, Edelman ER. Tissue engineering therapy for cardiovascular disease. Circulation Research. 2003 May 30;92(10):1068-78. [PDF]

• Hwang CW, Wu D, Edelman ER. Impact of transport and drug properties on the local pharmacology of drug-eluting stents. International Journal of Cardiovascular Interventions. 2003;5(1):7-12. [PDF]

• Kolandaivelu K, Edelman ER. Low background, pulsatile, in vitro flow circuit for modeling coronary implant thrombosis. Journal of Biomechanical Engineering.2002 Dec;124(6):662-8. [PDF]

• Nugent HM, Groothuis A, Seifert P, Guerraro JL, Nedelman M, Mohanakumar T, Edelman ER. Perivascular endothelial implants inhibit intimal hyperplasia in a model of arteriovenous fistulae: a safety and efficacy study in the pig. Journal of Vascular Research. 2002 Nov-Dec;39(6):524-33. [PDF]

• Stultz CM, Levin AD, Edelman ER. Phosphorylation-induced conformational changes in a mitogen-activated protein kinase substrate. Implications for tyrosine hydroxylase activation. Journal of Biological Chemistry. 2002 Dec 6;277(49):47653-61. [PDF]

• Welt FG, Rogers C. Inflammation and restenosis in the stent era. Arteriosclerosis, Thrombosis and Vascular Biology. 2002 Nov 1;22(11):1769-76. [PDF]

• Schwartz RS, Edelman ER, Carter A, Chronos N, Rogers C, Robinson KA, Waksman R, Weinberger J, Wilensky RL, Jensen DN, Zuckerman BD, Virmani R. Drug-eluting stents in preclinical studies: recommended evaluation from a consensus group.. Circulation 2002 Oct 1;106(14):1867-73. [PDF]

• Lewis EF, Edelman ER. Acute ST depressions in a patient with idiopathic hypertrophic subaortic stenosis and normal coronary arteriesCirculation 2002 Aug 6;106(6):757-8. [PDF]

• Danenberg HD, Welt FG, Walker M 3rd, Seifert P, Toegel GS, Edelman ER. Systemic inflammation induced by lipopolysaccharide increases neointimal formation after balloon and stent injury in rabbits. Circulation. 2002 Jun 18. 105(24): 2917-22. [PDF]

• Balcells M, Edelman ER. Effect of Pre-Adsorbed Proteins on Attachment, Proliferation, and Function of Endothelial Cells. Journal of Cellular Physiology. 2002 May. 191: 155-161. [PDF]

• Hwang CW, Edelman ER. Arterial ultrastructure influences transport of locally delivered drugs. Circulation Research. 2002 Apr 19. 90(7): 826-832. [PDF]

• Welt FG, Horvath C, Nedelman M, Rao P, Rogers C. Targeting CCR2 or CD18 inhibits experimental in-stent restenosis in primates: inhibitory potential depends on type of injury and leukocytes targeted. Circulation Research. 2002 Mar 8; 90(4): 488-94. [PDF]

• Woods TC, Blystone CR, Yoo J, Edelman ER. Activation of EphB2 and its ligands promote vascular smooth muscle cell proliferation. Journal of Biological Chemistry. 2002 Jan 18. 277(3): 1924-7. [PDF]

• Welt FG, Woods TC, Edelman ER. Oral Heparin Prevents Neointimal Hyperplasia After Arterial Injury: Inhibitory Potential Depends on Type of Vascular Injury. Circulation. 2001 Dec 18. 104(25): 3121-3124. [PDF]

• Edelman ER. On Causes: Hippocrates, Aristotle, Robert Koch, and the Dread Pirate Roberts. Circulation. 2001 Nov 20. 104(21): 2509-2512. [PDF]

• Lovich MA, Creel CJ, Hong K, Hwang CW, Edelman ER. Carrier proteins determine local pharmacokinetics and arterial distribution of paclitaxel. Journal of Pharmaceutical Sciences. 2001 Sep. 90(9): 1324-1335. [PDF]

• Nugent HM, Edelman ER. Endothelial implants provide long-term control of vascular repair in a porcine model of arterial injury. Journal of Surgical Research. 2001 Aug. 99(2): 228-34. [PDF]

• Hwang CW, Wu D, Edelman ER. Physiological transport forces govern drug distribution for stent-based delivery. Circulation. 2001 Jul 31. 104(5): 600-605. [PDF] [COVER]

• Consi TR, Seifert PA, Triantafyllou MS, Edelman ER. The dorsal fin engine of the seahorse (Hippocampus sp.). Journal of Morphology. 2001 Apr. 248(1): 80-97. [PDF]

• Edelman ER, Seifert P, Groothuis A, Morss A, Bornstein D, Rogers C. Gold-coated NIR stents in porcine coronary arteries. Circulation. 2001 Jan 23. 103(3): 429-434. [PDF]

• Welt FG, Edelman ER, Simon DI, Rogers C. Neutrophil, not macrophage, infiltration precedes neointimal thickening in balloon-injured arteries. Arteriosclerosis, Thrombosis and Vascular Biology. 2000 Dec; 20(12): 2553-2558. [PDF]

• Drachman DE, Edelman ER, Seifert P, Groothuis AR, Bornstein DA, Kamath KR, Palasis M, Yang D, Nott SH, Rogers C. Neointimal thickening after stent delivery of paclitaxel: change in composition and arrest of growth over six months. Journal of the American College of Cardiology. 2000 Dec;36(7): 2325-2332. [PDF]

• Edelman ER, Nathan A, Katada M, Gates J, Karnovsky MJ. Perivascular graft heparin delivery using biodegradable polymer wraps. Biomaterials. 2000 Nov; 21(22): 2279-2286. [PDF]

• Elmalak O, Lovich MA, Edelman E. Correlation of transarterial transport of various dextrans with their physicochemical properties. Biomaterials. 2000 Nov; 21(22): 2263-2272. [PDF]

• Parikh SA, Edelman ER. Endothelial cell delivery for cardiovascular therapy. Advanced Drug Delivery Reviews. 2000 Aug; 42(1-2): 139-161. Review. [PDF]

• Ettenson DS, Koo EW, Januzzi JL, Edelman ER. Endothelial heparan sulfate is necessary but not sufficient for control of vascular smooth muscle cell growth. J Cell Physiol 2000 Jul;184(1): 93-100. [PDF]

• Nugent MA, Nugent HM, Iozzo RV, Sanchack K, Edelman ER. Perlecan is required to inhibit thrombosis after deep vascular injury and contributes to endothelial cell-mediated inhibition of intimal hyperplasia. Proceedings of the National Academy of Sciences U S A. 2000 Jun;97(12): 6722-6727. [PDF]

• Tavakkolizadeh A, Shen R, Abraham P, Kormi N, Seifert P, Edelman ER, Jacobs DO, Zinner MJ, Ashley SW, Whang EE. Glucagon-like peptide 2: a new treatment for chemotherapy-induced enteritis. Journal of Surgical Research. 2000 Jun; 91(1): 77-82. [PDF]

• Creel CJ, Lovich MA, Edelman ER. Arterial paclitaxel distribution and depostion. Circulation Research. 2000 Apr;86(8):879-884. [PDF] [Methods]

• Garasic JM, Edelman ER, Squire JC, Seifert P, Williams MS, Rogers C. Stent and artery geometry determine intimal thickening independent of arterial injury. Circulation. 2000 Feb;101(7): 812-8. [PDF]

• Simon DI, Dhen Z, Seifert P, Edelman ER, Ballantyne CM, Rogers C. Decreased neointimal formation in Mac-1(-/-) mice reveals a role for inflammation in vascular repair after angioplasty. Journal of Clinical Investigation. 2000 Feb;105(3): 293-300. [PDF]

• Noh I, Lovich MA, Edelman ER. Mechanisms of heparin transport through expanded poly(tetrafluoroethylene) vascular grafts. Journal of Biomedical Materials Research. 2000 Jan;49(1): 112-9. [PDF]

• Edelman ER. Vascular tissue engineering: designer arteries. Circ Res1999 Dec; 85(12): 1173-1178. [PDF]

• Laham RJ, Sellke FW, Edelman ER, Pearlman JD, Ware JA, Brown DL, Gold JP, Simons M. Local perivascular delivery of basic fibroblast growth factor in patients undergoing coronary bypass surgery: results of a phase I randomized, double-blind, placebo-controlled trial. Circulation. 1999 Nov;100(18): 1865-71. [PDF]

• Squire JC, Rogers C, Edelman ER. Measuring arterial strain induced by endovascular stents. Med Biol Eng Comput. 1999 Nov; 37(6):692-8. [PDF]

• Lovich MA and Edelman ER. Tissue concentration of heparin, not administered dose, correlates with the biological response of injured arteries in vivo. Proc Natl Acad Sci U S A. 1999 Sep 28. 96: 11111-11116. [PDF]

• Edelman ER, Rogers C. Stent-versus-stent equivalency trials : are some stents more equal than others? Circulation. 1999 Aug; 100(9): 896-8. [PDF]

• Wan WK, Lovich MA, Hwang CW, Edelman ER. Measurement of drug distribution in vascular tissue using quantitative fluorescence microscopy. J Pharma Sci 1999 Aug; 88(8): 822-829. [PDF]

• Nugent HM, Rogers C, Edelman ER. Endothelial Implants Inhibit Intimal Hyperplasia After Porcine Angioplasty. Circ Res 1999 Mar; 84(4): 384-391. [PDF]

• Rogers C, Tseng D, Squire JC, Edelman ER. Balloon-Artery Interactions During Stent Placement: A Finite Element Analysis Approach to Pressure, Compliance, and Stent Design as Contributors to Vascular Injury. Circ Res 1999 Mar; 84(4), 378-383. [PDF]

Pre-1999

• Rogers C, Edelman Er, Simon DI. A mAb to the β2--leukocyte integrin Mac-1 (CD11byCD18) reducesintimal thickening after angioplasty or stent implantation in rabbits. Proc Natl Acad Sci USA 1998 Aug;95(17):10134-9. [PDF]

• Yu C, Cunningham M, Rogers c,Dinbergs ID, Edelman ER. The biologic effects of growth factor-toxin conjugates in models of vascular injury depend on dose, mode of delivery, and animal species. J Pharm Sci 1998 Nov;87(11):1300-4. [PDF]

• Sellke FW, Laham RJ, Edelman ER, Pearlman JD, Simons M. Therapeutic angiogenesis with basic fibroblast growth factor: Technique and early results. Ann Thorac Surg 1998 Jun;65(6):1540-4. [PDF]

• Lovich MA, Brown LR, Edelman ER. Drug clearance and arterial uptake after local perivascular delivery to the rat carotid artery. J Am Coll Cardiol 1997 Jun;29(7):1645-50. [PDF]

• Lopez JJ, Edelman ER, Stamler A, Hibberd MG, Prasad P, Caputo RP, Carrozza JP, Douglas PS, Sellke FW, Simons M. Basic fibroblast growth factor in a porcine model of chronic myocardial ischemia: a comparison of angiographic, echocardiographic and coronary flow parameters. J Pharmacol Exp Ther 1997 Jul; 282(1):385-90. [PDF]

• Brown LR, Edelman ER, Fischel-Ghodsian F, Langer RS. Characterization of glucose-mediated insulin release from implantable polymers J Pharm Sci 1996 Dec; 85(12):1341-5. [PDF]

• Lovich MA, Edelman ER. Tissue average binding and equilibrium distribution: An example with heparin in arterial tissues. Biophys J 1996 Mar; 70(3):1553-9. [PDF]

• Nathan A, Nugent MA, Edelman ER. Tissue engineered perivascular endothelial cell implants regulate vascular injury. Proc Natl Acad Sci USA 1995 Aug;92(18):8130-4. [PDF]

• Lovich MA, Edelman ER. Mechanisms of transmural heparin transport in the rat abdominal aorta after local vascular delivery. Circ Res 1995 Dec;77(6):1143-50. [PDF]