Overview (Week 1)

Lecture 9/8

Functional Neural Systems (Weeks 2 & 3)

Reading list.

Please note: reading that are assigned from texts other than the course textbook are supplementary.

Lecture 9/13

Overview of Neuroanatomy - handout.

Lecture 9/15

Discussion 9/15

Randy Gollub, MD. PhD.: Human Subjects Safety Handout.

Lecture 9/20

Lab 9/20

Imaging Physiology (Weeks 3, 4 & 5)

Discussion 9/22

Waldvogel D, van Gelderen P, Muellbacher W, Ziemann U, Immisch I, Hallett M. The relative metabolic demand of inhibition and excitation. Nature. 2000 Aug 31;406(6799):995-8.

Discussant: Rick Hoge
Presenter: Steven Ulich

Lecture 9/22

Robert Banzett, Ph.D.: Respiratory & CV physiology for fMRI.

Lecture 9/27

Robert Banzett, Ph.D.: Cerebral physiology for fMRI.

Lab 9/27
To be determined

Lecture 9/29
To be determined

Discussion 9/29

Lecture 10/4
To be determined

Experiment Design (Weeks 5 & 6)

Lecture 10/6
O'Craven KM, Rosen BR, Kwong KK, Treisman A and Savoy R, Voluntary attention modulated fMRI activity in human MT-MST (1997). Neuron 18: 591-598.

Discussion 10/6

Schultz, Gauther, et al. Abnormal Ventral Temporal Cortical Activity During Face Discrimination Among Individuals With Autism and Asperger Syndrome. Arch Gen Psychiatry Vol 57, April 2000 Pg. 331

Hadjikhani, Joseph, Snyder et al. Activation of the fusiform gyrus when individuals with autism spectrum disorder view faces. NeuroImage 22 (2004) 1141­ 1150

Discussant: Nouchine Hadjikhani
Presenters: Christina and Becca.

Lecture 10/13
To be determined

Discussion 10/13

Blood AJ, Flaherty AW, Choi JK, Hochberg FH, Greve DN, Bonmassar G, Rosen BR, Jenkins BG. Basal ganglia activity remains elevated after movement in focal hand dystonia. Ann Neurol 2004; 55(5):744-8

Discussant: Anne Blood
Presenter: TBD


Physics of Image Acquisition (Weeks 7, 8 9 & 10 )

Lecture 10/18
To be determined

Lab 10/18
To be determined

Lecture 10/20
To be determined

Discussion 10/20

TBD

Discussant: Dan Sodickson
Presenter: TBD

Lecture 10/25
To be determined

Lab 10/25
To be determined

Lecture 10/27
To be determined

Discussion 10/27
To be determined

Lecture 11/1
To be determined

Discussion 11/1
To be determined

Lecture 11/3
To be determined

Discussion 11/3
To be determined

Lecture 11/8
To be determined

Lab 11/8
To be determined

Statistical Analysis (Weeks 11, 12 & 13)

Lecture 11/15
To be determined

Lab 11/15
To be determined

Lecture 11/17
To be determined

Discussion 11/17

Leite FP, Tsao D, Vanduffel W, Fize D, Sasaki Y, Wald LL, Dale AM, Kwong KK, Orban GA, Rosen BR, Tootell RB, Mandeville JB. Repeated fMRI using iron oxide contrast agent in awake, behaving macaques at 3 Tesla. Neuroimage. 2002 Jun;16(2):283-94

Discussant: Joe Mandeville
Presenter: TBD

Lecture 11/22
To be determined

Lab 11/22
To be determined

Lecture 11/24
To be determined

Lecture 12/1
To be determined

Discussion 12/1

Nature. 2003 Oct 30;425(6961):954-6. Spontaneously emerging cortical representations of visual attributes. Kenet T, Bibitchkov D, Tsodyks M, Grinvald A, Arieli A

Ikegaya Y, Aaron G, Cossart R, Aronov D, Lampl I, Ferster D, Yuste R. Synfire chains and cortical songs: temporal modules of cortical activity. Science. 2004 Apr 23;304(5670):559-64

Discussant: Chris Moore
Presenter: TBD


Structural and Functional Analysis (Week 14)

Lecture 12/6
To be determined

Lecture 12/8
To be determined

Discussion 12/8
To be determined

 

Supplementary Reading

Suggested for students with no prior neuroscience background

• Chapters from The Human Brain: An Introduction to Its Functional Anatomy. J. Nolte
  - Ch. 1: Introduction to the Nervous System
  - Ch. 3: Gross Anatomy and General Organization of the Central Nervous System

Suggested for students with no prior statistics background

• Chapters from Probability and Statistics. M. H. DeGroot and M. J. Schervish
  - Ch. 1: Introduction to Probability
  - Ch. 2: Conditional Probability

Texts to supplement physiology lectures:

• Pulmonary Physiology and Pathophysiology: An Integrated, Case-Based Approach by John B. West, Paperback 1st edition (January 15, 2001) Lippincott Williams & Wilkins Publishers; ISBN: 0781729106
  Amazon Price: $31.95
  Widely used by medical students. Not much depth on neurophysiology of breathing, but good for gas exchange etc.
• Cardiopulmonary System, Daniel R. Richardson, David C. Randall, Dexter F. Speck, Paperback - (January 15, 1998) 353 pages, Amazon Price: $25.95
  This book not known to me, but Dexter Speck is a good respiratory neurophysiologist
• Pulmonary Physiology, Michael G. Levitzky, 320 pages 5th edition (1999) McGraw-Hill Professional Publishing; ISBN: 0071345434, Amazon Price: $29.95
  I'm told by a colleague this is a good book.
• Human Physiology: The Mechanisms of Body Function, Arthur Vander, James Sherman, Dorothy Lucian 864 pages 8th edition Book&CDROM (2000) Amazon Price: $119.45 McGraw-Hill Higher Education; ISBN: 0072378441
  This is a readable and reliable text covering all systems -- We have used it for years in my department.

 

Materials currently or to be soon found on reserve in the Hayden Science Library (14S-100):

Reference Books

• 1. Functional Magnetic Resonance Imaging, S. A. Huettel, A. W. Song, and G. McCarthy, Sinauer, April 2004, ISBN 0-87893-288-7.
• 2. The Human Brain: An Introduction to Its Functional Anatomy, J. Nolte, C. V. Mosby, 5th edition, January 2002, ISBN 0-32301-320-1.
• Functional MRI: An Introduction to Methods. P. Jezzard, P. M. Matthews, S. M. Smith, eds. Oxford University Press (2001). ISBN 0-19-263071-7
• 3. Cerebral Blood Flow and Metabolism. L. Edvinsson and D. N. Krause, eds. Second edition. Lippincott, Williams & Wilkins (2002). ISBN 0-7817-2259-4.
• 4. Introduction to Functional Magnetic Resonance Imaging: Principles and Techniques. R. Buxton, ed. Cambridge University Press (2002). ISBN 0-521-58113-3.
• 5. Functional MRI: An Introduction to Methods. P. Jezzard, P. M. Matthews, S. M. Smith, eds. Oxford University Press (2001). ISBN 0-19-263071-7
• 6. Vander, Sherman, Luciano's Human Physiology: The Mechanisms of Body Function. Eric P. Widmaier, Hershel Raff, Kevin T. Strang. McGraw Hill (2002). 9th edition. ISBN 0-0724-3793-6.
• 7. Probability and Statistics. M. H. DeGroot and M. J. Schervish. Addison-Wesley Press (2001). 3rd edition. ISBN 0-201-52488-0.
• 8. Cognitive Neuroscience. Michael S. Gazzaniga, Richard B. Ivry, George R. Mangun. Norton & Company (2002). 2nd edition. ISBN 0-393-97777-3.
• 9. The Brain Atlas. Joseph Hanaway, Thomas A. Woolsey, Mokhtar Gado, Melville P. J. R. Roberts. Wiley & Sons Inc. (1998). ASIN 1891786067.

Introductory material on Fourier transforms:

• Signals and Systems Made Ridiculously Simple. Z. Z. Karu, ZiZi Press (1995). Chapter 16: Fourier Transforms

Miscellaneous Useful Materials:

• Chapters from Magnetic Resonance Imaging: Physical Principles and Sequence Design. Haacke, Brown, Thompson and Venkatesan
  - Ch. 1: Magnetic Resonance Imaging: A Preview
  - Ch. 2: Clasical Nucleus in Magnetic Field
  - Ch. 3: Rotating Reference Frames and Resonance
  - Ch. 4: Magnetization, Relaxation and the Bloch Equation
  - Ch. 41: MRI I: The Quantum View of Nuclear Magnetic Resonance Imaging
  - Ch. 42: MRI II: The Classical View of Nuclear Magnetic Resonance Imaging
  - Ch. 43: MRI III: Relaxation Times, Pulse Sequences, and Image Contrast
  - Ch. 44: MRI IV: Imaging
• Chapters from The Fast Fourier Transform and its applications. E. O. Brigham
  - Ch. 2: The Fourier Transform
  - Ch. 3: Fourier Transform Properties
  
• Chapters from NMR Tomography, Diffusometry, Relaxometry. R. Kimmich
  - Ch. 24: Survey
  - Ch. 25: Fundamentals of NMR Imaging
• Chapters from: Functional MRI. C.T.W. Moonen and P.A. Bandettini (1999)
  - Ch. 11: Basic Theoretical Models of BOLD Signal Change. R. M. Weisskoff
  - Ch. 13: Echo-Planar Imaging and Functional MRI. M. S. Cohen
  - Ch. 16: Physiological Noise: Strategies for Correction. P. Jezzard.
• An Introduction to NMR Imaging: From the Bloch equation to the imaging equation. W. S. Hinshaw and A. H. Lent, Proc. IEEE, Vol. 71, No. 3, March 1983.
• M. Mesulam, From Sensation to Cognition, Brain (1998), 121, 1013-1052.