HST.021/HST.020
Musculoskeletal Pathophysiology
Dwight R.Robinson
Mon, Wed, Fri, Jan 8, 10, 12, 17, 19, 22, 24, 26, 29, 31, 2, 09-11:30am, HAR-MED MEC 209
Pre-register on WebSIS and attend first class.
Prereq: Permission of instructor
Level: H 6 units Standard A - F Grading
Growth and development of normal bone and joints, the process of mineralization, the biophysics of bone and response to stress and fracture, calcium and phosphate homeostasis and regulation by parathyroid hormone and vitamin D, and the pathogenesis of metabolic bone diseases and disease of connective tissue, joints, and muscles, with consideration of possible mechanisms and underlying metabolic derangements. Enrollment limited. (Only HST students may register under HST.020, graded P/D/F.)
Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu
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HST.146/HST.147
Human Intermediary Metabolism
John A Badwey
Tue, Thu, Jan 9, 11, 16, 18, 23, 25, 30, 1, 09:30-11:30am, HAR-MED MEC 209
Pre-register on WebSIS and attend first class.
Prereq: Undergraduate course in biochemistry, or permission of instructor
Level: H 6 units Graded P/D/F
See description under subject HST.147.
Note:HST.146/147 is a units-to-be arranged subject, usually 6 units.
Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu
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HST.147/HST.146
Human Intermediary Metabolism
John A Badwey
Tue, Thu, Jan 9, 11, 16, 18, 23, 25, 30, 1, 09:30-11:30am, HAR-MED MEC 209
Pre-register on WebSIS and attend first class.
Prereq: Undergraduate subject in biochemistry or permission of instructor
Level: U 6 units Standard A - F Grading
First-year intensive subject in human biochemistry and physiological chemistry that focuses on intermediary metabolism and structures of key intermediates and enzymes important in human disease. Subject is divided into 4 groups: lipid, protein, carbohydrate, and nucleic acids. The importance of these areas is underscored with examples from diseases and clinical correlations. (Only HST students may register under HST.146, graded P/D/F.)
Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu
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HST.190/HST.191
Statistical Planning and Analysis of Biomedical Investigations
Dianne Finkelstein
Mon, Wed, Fri, Jan 8, 10, 12, 17, 19, 22, 24, 26, 29, 31, 2, 01:30-03:30pm, HAR-MED MEC 209
Pre-register on WebSIS and attend first class.
Prereq: 18.02
Level: H 6 units Graded P/D/F
See HST.191 for description. (Only HST students may register under HST.190, graded P/D/F.)
Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu
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HST.191/HST.190
Statistical Planning and Analysis of Biomedical Investigations
Dianne Finkelstein
Mon, Wed, Fri, Jan 8, 10, 12, 17, 19, 22, 24, 26, 29, 31, 2, 01:30-03:30pm, HMS MEC-209
Pre-register on WebSIS and attend first class.
Prereq: 18.02
Level: H 6 units Standard A - F Grading
Introduces statistical logic and technique as a basis for clinical decisions and scientific inference. Students learn to perform elementary statistical calculations, use a statistics computer program (STATA), and acquire the concepts and vocabulary to read biomedical literature critically and communicate productively with statistical professionals. Includes probability theory, normal sampling, chi-square and t-tests, analysis of variance, linear regression, and survival analysis. Case studies include applications to diagnostic screening, clinical drug trials, and physiological experiments. Emphasis on experimental studies rather than epidemiology. (Only HST students may register under HST.190, graded P/D/F.)
Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu
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HST.505
Laboratory in Molecular and Cellular Sciences
Laboratory in Molecular and Cellular Sciences
Jeffrey R Morgan
Mon-Fri, Jan 8-12, 15-19, 22, 24, 26, 08am-05:30pm, MIT bldg 4-253
Pre-register on WebSIS and attend first class.
Prereq: Biochemistry or cell biology
Level: H 12 units Standard A - F Grading
Subject provides hands-on laboratory training in state-of-the-art experimental approaches and techniques in molecular and cellular sciences. Lab training is reinforced with didactic lectures which stress the theory behind these methodologies. Topics covered include: mammalian cell culture, tissue engineering, DNA cloning, gene transfer and gene therapy, transgenic animals, protein purification and analysis, and microscopy. Emphasis on the quantitative aspects of these methodologies. Students learn how to incorporate these approaches into an interdisciplinary research strategy aimed at addressing important questions in biomedical research.
Subject provides hands-on laboratory training in state-of-the-art experimental approaches and techniques in molecular and cellular sciences. Lab training is reinforced with didactic lectures which stress the theory behind these methodologies. For more information, see MIT Bulletin.
Contact: Jeffrey R Morgan, 371-4878, jmorgan@sbi.org
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HST.718
Anatomy of Speech and Hearing
Barbara C. Fullerton
Mon-Fri, Jan 8-12, 16-19, 22-26, 29-2, 09am-01:00pm, HAR-MED MEC
Pre-register on WebSIS and attend first class.
Prereq: 7.012 or 7.013 or 7.014
Level: H 6 units Standard A - F Grading
The anatomical structures of speech and hearing. Gross anatomy of the head and neck, cranial nerves, and the central nervous system. Laboratory exercises provide experience in dissection and the analysis of microscopic specimens.
Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu
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HST.935
Narrative Ethics: Literary Texts and Moral Issues in Medicine
Martha Montello
Tue, Thu, Jan 9, 11, 16, 18, 23, 25, 30, 1, 04-06:00pm, HAR-MED MEC 109
Pre-register on WebSIS and attend first class.
Prereq: —
Level: G 6 units Graded P/D/F
Eight-session subject uses literary narratives and poetry to study ethical issues in medicine. This methodology emphasizes the importance of context, contingency, and circumstance in recognizing, evaluating, and resolving moral problems. Focus on developing the skills of critical and reflective reading that increase effectiveness in clinical medicine. Texts include short fiction and poetry by Woolf, Chekhov, Carver, Kafka, Hurston, Marquez, and Tolstoy. Instructor provides necessary philosophic and literary context followed by class discussion. Students keep a reading journal that examines the meanings of illness, the moral role of the physician, and the relevance of emotions, culture, faith, values, social realities, and life histories to patient care.
This eight-session course, especially suited for a mixed group of first, second, third, and fourth-year students, uses literary narratives and poetry to study ethical issues in medicine. This methodology emphasizes the importance of context, contingency, and circumstance in recognizing, evaluating, and resolving moral problems. The seminar will focus on developing the skills of critical and reflective reading that increase effectiveness in clinical medicine. Text will include short fiction and poetry by Woolf, Chekov, Carver, Kafka, Hurston, Marquez, and Tolstoy. The instructor will provide necessary philosophic and literary context at the beginning of each session, the balance devoted to class discussion. During the course, students will keep a reading journal that examines the meanings of illness, the moral role of the physician, and the relevance of emotions, culture, faith, values, social realities, and life histories to patient care.
Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu
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