HST.021/HST.020
Musculoskeletal Pathophysiology
Dwight R.Robinson
Mon, Wed, Fri, Jan 7, 9, 11, 14, 16, 18, 23, 25, 28, 30, 1, 09-11:30am, MEC-209
Pre-register on WebSIS and attend first class.
Prereq: Enrollment limited, open only to medical and graduate students
Level: H 6 units Standard A - F Grading
Growth and development of normal bone and joints, the process of mineralization, the biophysics of bone and response to stress and fracture, calcium and phosphate homeostasis and regulation by parathyroid hormone and vitamin D, and the pathogenesis of metabolic bone diseases and disease of connective tissue, joints, and muscles, with consideration of possible mechanisms and underlying metabolic derangements. Enrollment limited. (Only HST students may register under HST.020, graded P/D/F.)
Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu
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HST.181/HST.180
Genetics in Medicine
Bruce R. Korf
Tue, Thu, Jan 8, 10, 15, 17, 22, 24, 29, 31, 01-03:00pm, 56-154
Prereq: 7.012 or 7.013 or 7.014, 7.05
Level: H 6 units Standard A - F Grading
Introduction to central issues in medical genetics. Significance of karyotypic analysis in clinical genetics and oncology. In-depth consideration of well-defined, genetically based illnesses including cystic fibrosis, muscular dystrophies, and Huntington's disease. Clinical issues posed by predisposition to common forms of illness such as diabetes, atherosclerosis, and specific forms of cancer addressed from a molecular genetic perspective. Includes patient presentations, consideration of genetic counseling issues, and the likely clinical impact of new genetic diagnostic techniques. (Only HST students may register under HST.180, graded P/D/F.)
Enrollment limited to medical and graduate students
Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu
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HST.191/HST.190
Statistical Planning and Analysis of Biomedical Investigations
Dianne Finkelstein
Mon, Wed, Fri, Jan 7, 9, 11, 14, 16, 18, 23, 25, 28, 30, 1, 01:30-03:30pm, MEC-209
Pre-register on WebSIS and attend first class.
Prereq: Enrollment limited, open only to medical and graduate students, 18.02
Level: H 6 units Standard A - F Grading
Introduces statistical logic and technique as a basis for clinical decisions and scientific inference. Students learn to perform elementary statistical calculations, use a statistics computer program (STATA), and acquire the concepts and vocabulary to read biomedical literature critically and communicate productively with statistical professionals. Includes probability theory, normal sampling, chi-square and t-tests, analysis of variance, linear regression, and survival analysis. Case studies include applications to diagnostic screening, clinical drug trials, and physiological experiments. Emphasis on experimental studies rather than epidemiology. (Only HST students may register under HST.190, graded P/D/F.)
Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu
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HST.505
Laboratory in Molecular and Cellular Sciences
Jeffrey R Morgan
Mon-Fri, Jan 7-11, 14-18, 22-25, 28-1, 08am-05:30pm, TBA
Pre-register on WebSIS and attend first class.
Prereq: Biochemistry or cell biology
Level: H 12 units Standard A - F Grading
Subject provides hands-on laboratory training in state-of-the-art experimental approaches and techniques in molecular and cellular sciences. Lab training is reinforced with didactic lectures which stress the theory behind these methodologies. Topics covered include: mammalian cell culture, tissue engineering, DNA cloning, gene transfer and gene therapy, transgenic animals, protein purification and analysis, and microscopy. Emphasis on the quantitative aspects of these methodologies. Students learn how to incorporate these approaches into an interdisciplinary research strategy aimed at addressing important questions in biomedical research.
For more information, see MIT Bulletin.
Contact: Jeffrey R. Morgan, E25-518, (617) 371-4878, jmorgan@sbi.org
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HST.718
Anatomy of Speech and Hearing
Barbara C. Fullerton
Mon-Fri, Jan 7-11, 14-18, 22-25, 28-1, 09am-01:00pm, MEC-443
Pre-register on WebSIS and attend first class.
No listeners
Prereq: 7.012 or 7.013 or 7.014
Level: H 6 units Standard A - F Grading
The anatomical structures of speech and hearing. Gross anatomy of the head and neck, cranial nerves, and the central nervous system. Laboratory exercises provide experience in dissection and the analysis of microscopic specimens.
Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu
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HST.935
Narrative Ethics: Literary Texts and Moral Issues in Medicine
Martha Montello
Tue, Thu, Jan 8, 10, 15, 17, 22, 24, 29, 31, 04-06:00pm, MEC-209
Pre-register on WebSIS and attend first class.
Prereq: Enrollment limited, open only to medical and graduate students
Level: G 6 units Graded P/D/F
Eight-session subject uses literary narratives and poetry to study ethical issues in medicine. Methodology emphasizes the importance of context, contingency, and circumstance in recognizing, evaluating, and resolving moral problems. Focus on developing the skills of critical and reflective reading that increase effectiveness in clinical medicine. Texts include short fiction and poetry by Woolf, Chekhov, Carver, Kafka, Hurston, Marquez, and Tolstoy. Instructor provides necessary philosophic and literary context followed by class discussion. Students keep a reading journal that examines the meanings of illness, the moral role of the physician, and the relevance of emotions, culture, faith, values, social realities, and life histories to patient care.
Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu
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