HST.021/HST.020
Musculoskeletal Pathophysiology
Dwight R.Robinson
Mon, Wed, Fri, Jan 3, 5, 7, 10, 12, 14, 19, 21, 24, 26, 28, 09-11:30am, MEC 209
Pre-register on WebSIS and attend first class.
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Prereq: Permission of Instructor
Level: H 6 units Standard A - F Grading
Growth and development of normal bone and joints, the process of mineralization, the biophysics of bone and response to stress and fracture, calcium and phosphate homeostasis and regulation by parathyroid hormone and vitamin D, and the pathogenesis of metabolic bone diseases and disease of connective tissue, joints, and muscles, with consideration of possible mechanisms and underlying metabolic derangements. (Only HST students may register under HST.020, graded P/D/F.) Enrollment is limited and only open to medical and graduate students.
Contact: Amy Magiera, E25-518, 258-7084, amagiera@mit.edu
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HST.146/HST.147
Human Biochemistry and Metabolic Diseases
Charles Serhan
Tue, Thu, Jan 4, 6, 11, 13, 18, 20, 25, 27, 08:30am-12:30pm, MEC 209--HMS
Pre-register on WebSIS and attend first class.
Prereq: Permission of instructor
Level: H 6 units Graded P/D/F
First-year graduate level intensive subject in human biochemistry and physiological chemistry that focuses on intermediary metabolism and structures of key intermediates and enzymes important in human disease. Subject is divided into four areas: carbohydrates, lipids, amino acids and nucleic acids. The importance of these areas is underscored with examples from diseases and clinical correlations. (Only HST students may register under HST.146, graded P/D/F.) Enrollment limited.
Note:HST.146/147 is a units-to-be arranged subject, usually 6 units. Enrollment is open to graduate and medical students.
Contact: Amy Magiera, E25-518, 258-7084, amagiera@mit.edu
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HST.190/HST.191
Statistical Planning and Analysis of Biomedical Investigations
Rebecca Betensky, Miguel Hernan
Mon, Wed, Fri, Jan 3, 5, 7, 10, 12, 14, 19, 21, 24, 26, 28, 01:30-03:30pm, MEC 209--HMS
Pre-register on WebSIS and attend first class.
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Prereq: 18.02
Level: H 6 units Graded P/D/F
See HST.191 for description. (Only HST students may register under HST.190, graded P/D/F.) Enrollment limited to Medical and Graduate Students
Contact: Amy Magiera, E25-518, 258-7084, amagiera@mit.edu
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HST.480
Special Subjects in Health Sciences and Technology
Bioinformatics and Proteomics: An Engineering-Based Problem Solving Approach
G. Alterovitz, M. Ramoni, M. Kellis
Tue, Thu, Jan 4, 6, 11, 13, 18, 20, 25, 27, 11am-12:30pm, 3-133, LAB: TR 9-11 am, 37-212
Pre-register on WebSIS and attend first class.
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Prereq: 7.012, or equivalent; 6.003 or equivalent; 6.041 or equivale
Level: U 3 units Graded P/D/F Can be repeated for credit
Opportunity for group study of subjects related to Health Sciences and Technology not otherwise included in the curriculum. Offerings are initiated by HST faculty on an ad hoc basis subject to program approval. Prerequisites may vary by topic; consult faculty at time of offering.
Interdisciplinary, hands-on approach covers sequence analysis, microarray expression analysis, Bayesian methods, control theory, scale-free networks, and biotechnology applications. New research areas explored using literature and book chapter materials written by instructors. Lecturers from industry and academia. Graduate students particularly encouraged to register. Graduate level problem sets available for those who want them. Joint with EECS.
Contact: Gil Alterovitz, gil@mit.edu
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HST.505
Laboratory in Molecular and Cellular Sciences
Jeffrey R Morgan
Mon-Fri, Jan 3-7, 10-14, 18, 21, 09am-05:30pm, MGH and Shriners
Pre-register on WebSIS and attend first class.
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Prereq: Biochemistry or cell biology
Level: H 12 units Standard A - F Grading
Subject provides hands-on laboratory training in state-of-the-art experimental approaches and techniques in molecular and cellular sciences. Lab training is reinforced with didactic lectures which stress the theory behind these methodologies. Topics covered include: mammalian cell culture; tissue engineering; DNA cloning; gene transfer and gene therapy; transgenic animals; protein purification and analysis; and microscopy. Emphasis on the quantitative aspects of these methodologies. Students learn how to incorporate these approaches into an interdisciplinary research strategy aimed at addressing important questions in biomedical research.
Location and course times vary, please download the complete schedule at the website listed below.
Web: http://hst.mit.edu/images/upload/HST_505_Syllabus.pdf
Contact: Jeffrey R. Morgan, E25-518, (401) 863-9879, Jeffrey_Morgan@brown.edu
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HST.935
Narrative Ethics: Literary Texts and Moral Issues in Medicine
Martha Montello
Tue, Thu, Jan 4, 6, 11, 13, 18, 20, 25, 27, 04-06:00pm, MEC 445 and 447--HMS
Pre-register on WebSIS and attend first class.
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Prereq: —
Level: G 6 units Graded P/D/F
The eight-session subject uses literary narratives and poetry to study ethical issues in medicine. Methodology emphasizes the importance of context, contingency, and circumstance in recognizing, evaluating, and resolving moral problems. Focus on developing the skills of critical and reflective reading that increase effectiveness in clinical medicine. Texts include short fiction and poetry by Woolf, Chekhov, Carver, Kafka, Hurston, Marquez, and Tolstoy. Instructor provides necessary philosophic and literary context followed by class discussion. Students keep a reading journal that examines the meanings of illness, the moral role of the physician, and the relevance of emotions, culture, faith, values, social realities, and life histories to patient care. Enrollment is limited and only open to medical and graduate students.
Contact: Amy Magiera, E25-518, 258-7084, amagiera@mit.edu
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