IAP Independent Activities Period
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IAP 2009 Subjects

Health Sciences & Technology

HST.021/HST.020
Musculoskeletal Pathophysiology
Dr. Dwight Robinson
Mon, Wed, Fri, Jan 5, 7, 9, 12, 14, 16, 21, 23, 26, 28, 30, 09-11:30am, MEC 209

Pre-register on WebSIS and attend first class.
No listeners
Prereq: Permission of Instructor
Level: H 6 units Standard A - F Grading   

Growth and development of normal bone and joints, the process of mineralization, the biophysics of bone and response to stress and fracture, calcium and phosphate homeostasis and regulation by parathyroid hormone and vitamin D, and the pathogenesis of metabolic bone diseases and disease of connective tissue, joints, and muscles, with consideration of possible mechanisms and underlying metabolic derangements. Only HST students may register under HST.020, graded P/D/F. Enrollment limited. Open only to medical and graduate students.
This class is held in Boston at Harvard Medical School.
Contact: Dr. Dwight Robinson, robinson.dwight@mgh.harvard.edu

HST.146/HST.147
Human Biochemistry and Metabolic Diseases
Dr. David MacLaughlin
Tue, Thu, Jan 6, 8, 13, 15, 20, 22, 27, 29, 09am-12:30pm, MEC 209

Pre-register on WebSIS and attend first class.
Prereq: Permission of instructor
Level: H 6 units Graded P/D/F   

First-year graduate level intensive subject in human biochemistry and physiological chemistry that focuses on intermediary metabolism and structures of key intermediates and enzymes important in human disease. Subject is divided into four areas: carbohydrates, lipids, amino acids and nucleic acids. The importance of these areas is underscored with examples from diseases and clinical correlations. Only HST students may register under HST.146, graded P/D/F. Enrollment limited.
Enrollment open only to graduate and medical students. This class is located in Boston at Harvard Medical School.
Contact: Dr. David MacLaughlin, maclaugh@helix.mgh.harvard.edu

HST.190/HST.191
Introduction to Biostatistics and Epidemiology
Dr. Rebecca Betensky, Dr. Miguel Hernan
Mon, Wed, Fri, Jan 5, 7, 9, 12, 14, 16, 21, 23, 26, 28, 30, 01:30-04:00pm, MEC 209

Pre-register on WebSIS and attend first class.
No listeners
Prereq: GIR:CAL2
Level: H 6 units Graded P/D/F   

Fundamentals of biostatistics and epidemiology. Trains students how to comprehend, critique and communicate findings from biomedical literature. How to assess the importance of chance in the interpretation of experimental data. Topics include probability theory, normal sampling, chi-squared and t-tests, analysis of variance, linear regression and survival analysis, as well has how to perform elementary calculations using the statistical package STATA. How to identify and prevent bias in observational studies. Causal inference, types of bias (confounding, selection and information bias), key study designs (randomized trials, cohort and case-control studies, and screening programs). Only HST students may register under HST.190, graded P/D/F. Enrollment is limited and is only open to medical and graduate students.
Contact: Dr. Rebecca Betensky, betensky@hsph.harvard.edu

HST.211
Biomedical Enterprise Clinical Experience I
Dr. Rox Anderson, Dr. Warren Zapol
Tue, Thu, Jan 6, 8, 13, 15, 20, 22, 27, 29, 09am-05:00pm, MGH

Pre-register on WebSIS and attend first class.
Prereq: Permission of instructor
Level: H 6 units Standard A - F Grading   

Provides students with an understanding of the strategy, rules, design and conduct of human studies and clinical trials. Explore how, where, when and why medical practice and biomedical enterprise intersect. Interact with academic physicians engaged in development of technology, perform clinical autopsies on failed biomedical enterprises, and develop the knowledge base needed for elective clinical experiences. Restricted to HST BEP students. Contact: Beverly Dammin, MGH, bdammin@partners.org

HST.505
Laboratory in Molecular and Cellular Sciences
Dr. Jagesh Shah, J. Chen, U. Demirci, J. Karp
Mon-Fri, Jan 5-9, 12-16, 20-23, 26-30, 09am-05:00pm, E25-101 and E25-548

Pre-register on WebSIS and attend first class.
No listeners
Prereq: Biochemistry or cell biology
Level: H 12 units Standard A - F Grading   

Provides laboratory training in state-of-the-art experimental approaches and techniques in molecular and cellular sciences. Lab training is reinforced with didactic lectures which stress the theory behind these methodologies. Topics include mammalian cell culture; tissue engineering; DNA cloning; gene transfer and gene therapy; transgenic animals; protein purification and analysis; and microscopy. Emphasis on the quantitative aspects of these methodologies. Students learn how to incorporate these approaches into an interdisciplinary research strategy aimed at addressing important questions in biomedical research.
Locations. Labs (E25-548), Lectures (E25-101)
Contact: Traci Anderson, E25-518, (617) 253-7470, tanderso@mit.edu

HST.718
Anatomy of Speech and Hearing
Barbara C. Fullerton
Mon-Fri, Jan 5-9, 12-16, 20-23, 26-30, 09:30am-01:00pm, Harvard Med School

Pre-register on WebSIS and attend first class.
Limited to 12 participants.
No listeners
Prereq: GIR:BIOL, permission of instructor
Level: H 6 units Standard A - F Grading   

Study of the human body and brain, focusing on structures of the head and neck involved in speech and hearing. General organization of the nervous system and control of the peripheral structures. Involves dissection of a human cadaver and examination of brain specimens. Preference to students with some biology background and order of seniority of class.
Enrollment is limited; preference will be given to students with a biological background and in order of seniority of class.
Contact: Barbara C. Fullerton, Barbara_Fullerton@meei.harvard.edu

HST.960
At the Limits of Medicine: Philosophy, Religion, Literature
Dr. Susanne Klingenstein
Tue, Thu, Jan 6, 8, 13, 15, 20, 22, 27, 29, 02:30-04:00pm, MEC 212

Pre-register on WebSIS and attend first class.
Prereq: —
Level: G 4 units Graded P/D/F   

Critical examination of modern culture’s view of human beings (and God) and what it reveals about its attitude toward death. Students explore two descriptions of modern deaths, two essays contemplating the egocentric nature of man, the radical secularization of the concept of man in the 19th century, and two alternative views that restitute human goodness without religion or sentimentality.
Subject meets at the Harvard Medical School
Contact: Dr. Susanne Klingenstein, shalom@MIT.EDU


MIT  
Massachusetts Institute of Technology
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Last update: 30 September 2004