An Introduction to Genome Rearrangements in Evolution and Cancer: A Computational Perspective
Arjun(AJ) Bhutkar
Wed Jan 26, 02-03:30pm, 76-259
No enrollment limit, no advance sign up
Single session event
Prereq: None.
This non-credit class is intended to serve as a general introduction to computational models/formulations for analyzing the role of DNA rearrangements in shaping genomes and in genomic disorders. We will look at various types of rearrangements that occur during evolution (in the context of model organism and human genomes) and explore algorithms for comparative rearrangement analysis along with issues of computational complexity. Rearrangements can also lead to chromosomal abnormalities implicated in inherited diseases and cancer. We will survey genomic disorders with a focus on alterations frequently found in a variety of human cancers. Topics also include: Genome synteny, breakpoint analysis, comparative metrics, rearrangement phylogenies.
Contact: Arjun(AJ) Bhutkar, E18-366, (617) 324-7642, arjun@mit.edu
Sponsor: David H. Koch Inst. for Integrative Cancer Researc
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Seminar Series on Molecular Approaches to Evolution
Prof. Michael Laub
No enrollment limit, no advance sign up
Participants welcome at individual sessions (series)
Prereq: none
January 31, 2011 11am - 12pm Whitehead Auditorium
Web: http://web.mit.edu/biology/www/biology/iap.html
Contact: Prof. Michael Laub, 68-580A, x4-0418, laub@mit.edu
Sponsor: Biology
"The puzzling coexistence of antibiotic resistant and sensitive microbes in the natural environment"
Roy Kishony, Associate Professor, Department of Systems Biology, Harvard Medical School
Thu Jan 6, 11am-12:00pm, Broad Auditorium, NE30-1154
"I might like you better if we stuck together: the social biology of sucrose utilization in budding yeast"
Andrew Murray, Professor, Department of Molecular and Cellular Biology, Harvard University
Tue Jan 11, 11am-12:00pm, Whitehead Auditorium
"Chromatin dynamics in fungi: from 15 minutes to 1 billion years"
Ollie Rando, Assistant Professor, Department of Biochemistry and Molecular Pharmacology, U. Mass Medical School
Please note: different starting time
Tue Jan 18, 10-11:00am, Whitehead Auditorium
"Our sex chromosomes: 300 million years in the making"
David Page, Professor, Department of Biology, MIT, Whitehead Institute, Howard Hughes Medical Institute
Fri Jan 21, 11am-12:00pm, Whitehead Auditorium
"Origins of quantitative spatiotemporal gene expression variation in Drosophila blastoderm embryos"
Angela DePace, Assistant Professor, Department of Systems Biology, Harvard University
\*\*\* THIS EVENT IS ACTUALLY BEING HELD ON January 31, 2011
Sun Jan 30, 11am-12:00pm, Whitehead Auditorium
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Single-Particle Electron Microscopy
Dr. James Chen
Tue Jan 18, Thu Jan 20, Tue Jan 25, Thu Jan 27, 02-03:00pm, 68-181
No enrollment limit, no advance sign up
Recent advances in single-particle electron microscopy (EM), and cryo-EM in particular, have enabled structural analysis of macromolecular complexes at sub-nanometer and even near-atomic resolution. Complementary to X-ray crystallography and NMR spectroscopy, single-particle EM is unique in its capability to elucidate the structures of large molecular assemblies in their native states. In this seminar series, I will introduce the theoretical foundation as well as the basic experimental techniques of single-particle EM. The topics will include: the electron microscope instrument, sample preparation, data acquisition, image analysis, model reconstruction, and software hands-on practice. This course will emphasize on basic principles and concept (rather than on math and algorithms), and is open to the entire MIT biology research community (undergraduates, graduates, postdocs and faculty members).
PLEASE NOTE: The January 27 class will meet in Room 68-474.
Contact: Dr. James Chen, 68-480, x3-8688, jzchen@mit.edu
Sponsor: Biology
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Taking the Next Step in Academic Science
Biology Postdoc Association & Biology Graduate Students
No enrollment limit, no advance sign up
Participants welcome at individual sessions (series)
Prereq: none
MIT Biology is also offering a selection of talks on the practice of science, navigating academia, and balancing it all with a life outside the lab.
Web: http://web.mit.edu/biology/www/biology/iap.html
Contact: Michael Laub, 68-580A, x4-0418, laub@mit.edu
Sponsor: Biology
Finding a Postdoc
Alan Grossman, Bart Hendriks, Caterina Schweidenback
Are you interested in doing a postdoc? Want to learn about an industry postdoc? Come hear about the details of interview/application from a professor, princple scientist and an MIT graduate who is currently a postdoc. Find out what makes a good postdoc candidate from a faculty perspective and what makes a good postdoc experience in industry or academia.
Thu Jan 6, 01-02:30pm, 68-181
Time Management
J. Kamens, S. Dasgupta, I. Cheeseman, D. Kim
Being successful in careers in the life sciences largely depends on the ability to efficiently manage several tasks both at work and at home. Come learn from professionals and scientists in academia and industry their tactics to get the job done while maintaining a good work-life balance.
Fri Jan 7, 01:30-03:00pm, 68-181
Finding a Faculty Position
Jonathan King, Amy Keating, Mary Gehring
Looking for that professorship is a daunting process. What do search committees look for? Where do you find information? What should you do at an interview? What are the pitfalls? Come find out from faculty at different career stages who have experienced all aspects of the process.
Thu Jan 13, 01-02:30pm, 68-181
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