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IAP 2012 Subjects

Health Sciences & Technology

HST.021/HST.020
Musculoskeletal Pathophysiology
Dr. Mary Bouxsein, Dr. Margaret Seton
Mon, Wed, Fri, Jan 9, 11, 13, 18, 20, 23, 25, 27, 30, 1, 3, 09am-12:00pm, HMS MEC 250

Pre-register on WebSIS and attend first class.
No listeners
Prereq: Permission of Instructor
Level: H 6 units Standard A - F Grading   

Growth and development of normal bone and joints, the process of mineralization, the biophysics of bone and response to stress and fracture, calcium and phosphate homeostasis and regulation by parathyroid hormone and vitamin D, and the pathogenesis of metabolic bone diseases and disease of connective tissue, joints, and muscles, with consideration of possible mechanisms and underlying metabolic derangements. Only HST students may register under HST.020, graded P/D/F. Enrollment limited; restricted to medical and graduate students.
This class is held at the Harvard Medical School.
Contact: Joseph R Stein, E25-518, (617) 452-4091, jrstein@mit.edu

HST.146/HST.147
Human Biochemistry and Metabolic Diseases
Dr. Richard Mitchell, Dr. David Cohen
Tue, Thu, Jan 10, 12, 17, 19, 24, 26, 31, 2, 08:30am-12:30pm, HMS MEC 209

Pre-register on WebSIS and attend first class.
Prereq: Permission of instructor
Level: H 6 units Graded P/D/F   

First-year graduate level intensive subject in human biochemistry and physiological chemistry that focuses on intermediary metabolism and structures of key intermediates and enzymes important in human disease. Subject is divided into four areas: carbohydrates, lipids, amino acids and nucleic acids. The importance of these areas is underscored with examples from diseases and clinical correlations. Only HST students may register under HST.146, graded P/D/F. Enrollment limited.
Enrollment open only to graduate and medical students. This class is located at the Harvard Medical School.
Contact: Joseph R.Stein, E25-518, (617) 452-4091, jrstein@mit.edu

HST.147/HST.146
Human Biochemistry and Metabolic Diseases
David Cohen, Richard Mitchell
Tue, Thu, Jan 10, 12, 17, 19, 24, 26, 31, 2, 08:30am-12:00pm, MEC 209 (HMS)

Pre-register on WebSIS and attend first class.
Prereq: Permission of instructor
Level: H 6 units Standard A - F Grading   

First-year graduate level intensive subject in human biochemistry and physiological chemistry that focuses on intermediary metabolism, structures of key intermediates and enzymes important in human disease. Subject is divided into four areas: carbohydrates, lipids, amino acids and nucleic acids. The importance of these areas is underscored with examples from diseases and clinical correlations that are introduced by clinician-scientists. Only HST students may register under HST.146, graded P/D/F. Enrollment limited. Contact: Joseph Stein, E25-518, 452-4091, jrstein@mit.edu

HST.190/HST.191
Introduction to Biostatistics and Epidemiology
Rebecca Betensky, Miguel Hernan
Mon, Wed, Fri, Jan 9, 11, 13, 18, 20, 23, 25, 27, 09:30-11:30am, MEC 209 (HMS)

Pre-register on WebSIS and attend first class.
No listeners
Prereq: GIR:CAL2
Level: H 6 units Graded P/D/F   

Fundamentals of biostatistics and epidemiology. Trains students how to comprehend, critique and communicate findings from biomedical literature. How to assess the importance of chance in the interpretation of experimental data. Topics include probability theory, normal sampling, chi-squared and t-tests, analysis of variance, linear regression and survival analysis, as well has how to perform elementary calculations using the statistical package STATA. How to identify and prevent bias in observational studies. Causal inference, types of bias (confounding, selection and information bias), key study designs (randomized trials, cohort and case-control studies, and screening programs). Enrollment limited; restricted to medical and graduate students. Contact: Joseph R. Stein, E25-518, 452-4091, jrstein@mit.edu

HST.191/HST.190
Introduction to Biostatistics and Epidemiology
Rebecca Betensky, Miguel Hernan
Mon, Wed, Fri, Jan 9, 11, 13, 18, 20, 23, 25, 27, 30, 1, 3, 09-11:30am, HMS MEC 209

Pre-register on WebSIS and attend first class.
No listeners
Prereq: GIR:CAL2
Level: H 6 units Standard A - F Grading   

Fundamentals of biostatistics and epidemiology. Trains students how to comprehend, critique and communicate findings from biomedical literature. How to assess the importance of chance in the interpretation of experimental data. Topics include probability theory, normal sampling, chi-squared and t-tests, analysis of variance, linear regression and survival analysis, as well has how to perform elementary calculations using the statistical package STATA. How to identify and prevent bias in observational studies. Causal inference, types of bias (confounding, selection and information bias), key study designs (randomized trials, cohort and case-control studies, and screening programs). Only HST students may register under HST.190, graded P/D/F. Enrollment limited; restricted to medical and graduate students.
This course meets at the Harvard Medical School.
Contact: Joseph Stein, E25-518, 452-4091, jrstein@mit.edu

HST.718
Anatomy of Speech and Hearing
Barbara C. Fullerton
Mon-Fri, Jan 9-13, 17-20, 23-27, 30-3, 09:30am-01:00pm, HMS

Pre-register on WebSIS and attend first class.
Limited to 12 participants.
No listeners
Prereq: GIR:BIOL, permission of instructor
Level: H 6 units Standard A - F Grading   

Studies the anatomy of the human head and neck, focusing on structures involved in speech and hearing. Covers general organization of the nervous system and control of the peripheral structures. Involves dissection of a human cadaver, examination of brain specimens, and analysis of cross-sectional radiographic images. Limited to 12; undergraduates admitted based on seniority.
NEW DESCRIPTION: Study of the anatomy of the human head and neck, focusing on structures involved in speech and hearing. General organization of the 
nervous system and control of the peripheral structures. Involves 
dissection of a human cadaver, examination of brain specimens, and analysis of cross-sectional radiographic images. Required graduate course for Program in Speech & Hearing Bioscience and Technology. Enrollment is limited to 12 and by permission only.
 Undergraduates may enroll if space is available. Preference is given in order of seniority. Contact: Barbara C. Fullerton, Barbara_Fullerton@meei.harvard.edu
Contact: Joseph R Stein, E25-518, x2-4091, jrstein@mit.edu

HST.S16
Special Subject: Health Sciences and Technology
Medical Decision Analysis and Diagnostic Test Interpretation
M. Brandon Westover, Sydney S. Cash, Matt T. Bianchi
Tue, Thu, Jan 10, 12, 17, 19, 24, 26, 02-05:00pm, HMS TMEC (TBD)

Pre-register on WebSIS and attend first class.
Limited to 8 participants.
No listeners
Prereq: Permission of Instructor
Level: G 4 units Graded P/D/F Can be repeated for credit   

Opportunity for group study of advanced subjects related to Health Sciences and Technology not otherwise included in the curriculum. Offerings are initiated by HST faculty on an ad hoc basis subject to program approval. Prerequisites may vary by topic; consult faculty at time of offering.
Teaches the essentials of quantitative diagnostic reasoning and medical decision analysis. Guides participants through the process of choosing an appropriate contemporary medical problem in which risk-benefit tradeoffs play a prominent role, conducting a decision analysis, and ultimately publishing the results in a medical journal. Topics include decision trees, influence diagrams, Markov decision models and Monte Carlo simulation, methods for quantifying patient values, Bayesian inference, decision thresholds, and the cognitive science of medical decision making.
Contact: Joseph R. Stein, E25-518, (617) 452-4091, jrstein@mit.edu


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Massachusetts Institute of Technology
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Last update: 7 Sept. 2011