A Look Inside the Human Brain
Dimitrios Pantazis, Director of MEG Lab
Enrollment: Limited: Advance sign-up required
Limited to 30 participants
Attendance: Participants welcome at individual sessions
Modern imaging technologies at MIT and MGH provide exciting new ways to understand the structure and function of the human brain. We will provide guided tours of our imaging facilities and show how we use these tools to look inside the brain. Our recently installed MEG scanner, capable of measuring magnetic fields a billionth of the magnetic field of earth, can record the simultaneous firing of thousands of cortical neurons as they form dynamic networks. Our MRI scanners provide high resolution images of the human brain as subjects perform a wide range of perceptual and cognitive tasks. Our PET scanners can identify and localize specific molecules in the brain, revealing pathologies that may underlie many different brain disorders. TMS is a noninvasive method that uses electromagnetic induction to create weak electric currents and cause depolarization or hyperpolarization in the neurons of the brain. NIRS uses infrared light to illuminate tissue and infer brain activity through the diffusion and scattering of this light. We will introduce these technologies, offer lab tours and demonstrate data collection, and discuss their contribution to neuroscience and current projects at MIT and MGH.
Contact: Dimitrios Pantazis, 46-5147, 617 324-6292, PANTAZIS@MIT.EDU
| Jan/15 | Wed | 01:00PM-02:30PM | 46-3015 |
Topics include MRI instrumentation, magnetic fields, safety, functional imaging with BOLD response, diffusion imaging, and others.
Anastasia Yendiki - Assistant Professor, Steven P Shannon - Operations Manager and MR Research Technologist, Sheeba Arnold Anteraper - MR Programmer, Atsushi Takahashi - Assistant Director, MR Physicist
| Jan/17 | Fri | 11:00AM-12:00PM | 46-1171 |
A tour at the MRI lab. Demo scan (finger tapping) and data analysis.
MRI Lab: http://mcgovern.mit.edu/technology/martinos-imaging-center/technical-resources
Steven P Shannon - Operations Manager and MR Research Technologist, Sheeba Arnold Anteraper - MR Programmer, Atsushi Takahashi - Assistant Director, MR Physicist
| Jan/22 | Wed | 01:00PM-02:30PM | 46-3015 |
Electrophysiological basis of MEG signals; instrumentation; modeling; cortical rhythms; brain networks; combining MEG with fMRI, studying the human visual system.
Dimitrios Pantazis - Director of MEG Lab, Yu-Teng Chang - Post-doctoral Associate, Radoslaw Cichy - Post-doctoral Associate
| Jan/22 | Wed | 02:30PM-04:00PM | 46-1147 |
A tour at the MEG Lab, demo scan and data analysis of an MEG experiment
MEG Lab: http://mcgovern.mit.edu/technology/meg-lab
Dimitrios Pantazis - Director of MEG Lab, Yu-Teng Chang - Post-doctoral Associate, Radoslaw Cichy - Post-doctoral Associate, Kleovoulos Tsourides - Research Associate
| Jan/24 | Fri | 01:00PM-02:30PM | 46-3015 |
Near Infrared Spectroscopy (NIRS) instrumentation, principles of light scattering and absorption, imaging of oxygenated hemoglobin, NIRS applications.
Juliette Selb - Instructor
| Jan/29 | Wed | 01:00PM-02:30PM | 46-3015 |
Use of Transcranial Magnetic Stimulation to depolarize and hyperpolarize neurons of the brain, applications to treat depression and examine basic mechanisms of post-traumatic stress disorder and anxiety, among others.
Tommi Raij - Instructor
| Jan/31 | Fri | 01:00PM-02:30PM | 46-3015 |
Seminar on Positron Emission Technology. Introduction to PET technology and scanners at MGH; applications in tumor detection; brain metabolic activity; gene expression; neurological diseases, such as Alzheimer¿s and Parkinson¿s; pharmacology etc.
Quanzheng Li - Assistant Professor
Big Data in Critical Care: Workshop & Conference
Leo Anthony Celi, Research Scientist - IMES
Enrollment: Limited: Advance sign-up required
Attendance: Participants welcome at individual sessions
On behalf of the MIT Institute for Medical Engineering and Science, Hacking Medicine and Beth Israel Deaconess Medical Center, we would like to invite you to attend the Big Data in Critical Care: Workshop & Conference.
The event will bring together various disciplines - computer science, medicine, nursing, pharmacy, biostatistics, epidemiology, informatics, business, health policy, and the social sciences - from both academia and industry, with the goal of learning from routinely collected clinical data, as outlined in a recent discussion paper from the Institute of Medicine.
Workshop - January 3rd-5th
Participants will be divided into teams of data scientists and clinicians who will use the MIMIC database to work on pre-selected clinical questions or projects. Findings will be presented at the end of the workshop. The best presentation will be awarded a cash prize as well as the opportunity to present at the conference. We are also inviting teams from around the world to participate via WebEx.
Conference - January 7th
The purpose of this one day event is to bring together clinicians and data scientists to learn about and discuss the oppportunities and challenges facing meaningful, secondary use of critical care data.
Keynote speakers: Professor Jeffrey Drazen, editor-in-chief of New England Journal of Medicine, and Professor John Ioannidis
4th Floor, Stata Center, MIT
32 Vassar Street, Cambridge, MA 02139
Register early: http://criticaldata.mit.edu/events.html
Sponsor(s): Institute for Medical Engineering & Science, SANA
Contact: Leo Anthony Celi, E25-505, (617) 253-7937, lceli@MIT.EDU
Bioinformatics for Beginners
Courtney Crummett, Bioinformatics and Biosciences Librarian
| Jan/08 | Wed | 03:00PM-04:30PM | 14N-132 DIRC |
| Jan/10 | Fri | 10:00AM-11:30AM | 14N-134 DIRC |
Enrollment: Unlimited: Advance sign-up required
Attendance: Participants welcome at individual sessions
The National Center for Biotechnology Information (NCBI) Entrez family of databases is the foundation of knowledge for molecular level bioscience research. Class attendees will learn about the organization and interconnectedness of NCBI databases while focusing on several specific databases. The session is a hands-on practicum and an excellent starting point for people who are new to or curious about bioinformatics research tools. This session is offered twice covering the same material; participants welcome at either session. Registration required.
Wednesday January 8th 3-4:30PM Please register at: http://libcal.mit.edu/event.php?id=488456.
Friday January 10th 10-11:30AM Please register at: http://libcal.mit.edu/event.php?id=488785.
Sponsor(s): Libraries, Biology
Contact: Courtney Crummett, 14S-134, 617 324-8290, CRUMMETT@MIT.EDU
Biotech Business Information for Engineers and Scientists
Courtney Crummett, Bioinformatics and Biosciences Librarian
| Jan/15 | Wed | 04:00PM-05:00PM | 14N-132 DIRC |
Enrollment: Limited: Advance sign-up required
Sign-up by 01/15
Limited to 30 participants
It's not brain surgery...it's market research. This session will introduce scientists and engineers to information resources that cover biotechnology industries and markets. We will use realistic examples and hands-on exercises with key resources to demonstrate how to match your ideas and discoveries with the opportunities and realities of the marketplace. Please register for this event.
If you're not interetsed in biotechnology a companion session will feature resources and examples geared for the engineering sciences:
Business information for engineers and scientists Tuesday Jan 28 4:00PM-5:00PM 14N-132 (DIRC)
Sponsor(s): Libraries, Biology
Contact: Courtney Crummett, 14S-134, 617 324-8290, CRUMMETT@MIT.EDU
Can We Innovate Our Way Out of the Healthcare Crisis?
Steven E. Locke, M.D.
| Jan/14 | Tue | 01:00PM-03:00PM | E17-133 |
| Jan/15 | Wed | 12:00PM-01:00PM | TMEC 212 (HMS) |
Enrollment: Unlimited: Advance sign-up required
Sign-up by 01/13
Attendance: Repeating event, particpants welcome at any session
You bet! Even during the government shut down, or during the time when websites don’t work properly. Innovation in healthcare to reduce cost while improving quality has led to development of technologies for patient engagement, electronic health records, mobile health, and other innovative technologies being part of the “medical home.” For the intended outcomes, we need innovation leaders who can think and act like entrepreneurs. The faculty of the HST.921 course, Enabling Technology Innovation in Healthcare and the Life Sciences, will present and discuss all aspects of the course -- including the mix of lectures by world leaders in medical informatics, skills-based tutorial sessions and faculty-mentored work on industry-sponsored projects.
We will conduct an experiential workshop in which student teams will collaborate in the impromptu design of a “device,” and we will test it and award a prize to the winning team.
Sponsor(s): Health Sciences & Technology
Contact: Mirena Bagur, 617 835-5019, mirena.bagur@gmail.com
Chemistry and Biology of Antibiotics
Jason Sello, MLK Visiting Associate Professor of Biology
Enrollment: Unlimited: No advance sign-up
Attendance: Participants welcome at individual sessions
Prereq: Background in organic chemistry, biochemistry, geneticsenet
An antibiotic is defined as a small molecule produced by a microorganism that kills or compromises the growth of another microorganism. These molecules are likely to be used for chemical defense in Nature, but they have long been exploited in biological research, biotechnology, and medicine.
This course is designed to highlight the connections between chemistry and biology. A wide array of topics at the interface of chemistry and biology will be covered. It is open to students with backgrounds in the biological and/or the physical sciences. It is expected that students with strong backgrounds in chemistry will learn fundamental concepts in biology; those with a strong knowledge in biology will learn fundamental concepts in chemistry. Some familiarity with basic concepts of organic chemistry, biochemistry, and genetics will be assumed.
Sponsor(s): Biology
Contact: Prof. Jason Sello, jsello@mit.edu
| Jan/06 | Mon | 03:30PM-05:00PM | 68-121 |
There will be 12 class sessions scheduled on January 6, 7, 8, 14, 15, 16, 21, 22, 27, 28, 29, 30.
First of 12.
Jason Sello - MLK Visiting Associate Professor of Biology
| Jan/07 | Tue | 03:30PM-05:00PM | 68-180 |
There will be 12 class sessions scheduled on January 6, 7, 8, 14, 15, 16, 21, 22, 27, 28, 29, 30.
2nd of 12.
Jason Sello - MLK Visiting Associate Professor of Biology
| Jan/08 | Wed | 03:30PM-05:00PM | 68-180 |
There will be 12 class sessions scheduled on January 6, 7, 8, 14, 15, 16, 21, 22, 27, 28, 29, 30.
3rd of 12.
Jason Sello - MLK Visiting Associate Professor of Biology
| Jan/14 | Tue | 03:30PM-05:00PM | 68-180 |
There will be 12 class sessions scheduled on January 6, 7, 8,, 14, 15, 16, 21, 22, 27, 28, 29, 30.
4th of 12.
Jason Sello - MLK Visiting Associate Professor of Biology
| Jan/15 | Wed | 03:30PM-05:00PM | 68-180 |
There will be 12 class sessions scheduled on January 6, 7, 8, 14, 15, 16, 21, 22, 27, 28, 29, 30.
5th of 12
Jason Sello - MLK Visiting Associate Professor of Biology
| Jan/16 | Thu | 03:30PM-05:00PM | 68-180 |
There will be 12 class sessions scheduled on January 6, 7, 8, 14, 15, 16, 21, 22, 27, 28, 29, 30.
6th of 12
Jason Sello - MLK Visiting Associate Professor of Biology
| Jan/21 | Tue | 03:30PM-05:00PM | 68-180 |
There will be 12 class sessions scheduled on January 6, 7, 8, 14, 15, 16, 21, 22, 27, 28, 29, 30.
7th of 12
Jason Sello - MLK Visiting Associate Professor of Biology
| Jan/22 | Wed | 03:30PM-05:00PM | 68-180 |
There will be 12 class sessions scheduled on January 6, 7, 8, 14, 15, 16, 21, 22, 27, 28, 29, 30.
8th of 12
Jason Sello - MLK Visiting Associate Professor of Biology
| Jan/27 | Mon | 03:30PM-05:00PM | 68-180 |
There will be 12 class sessions scheduled on January 6, 7, 8, 14, 15, 16, 21, 22, 27, 28, 29, 30.
9th of 12
Jason Sello - MLK Visiting Associate Professor of Biology
| Jan/28 | Tue | 03:30PM-05:00PM | 68-180 |
There will be 12 class sessions scheduled on January 6, 7, 8, 14, 15, 16, 21, 22, 27, 28, 29, 30.
10th of 12
Jason Sello - MLK Visiting Associate Professor of Biology
| Jan/29 | Wed | 03:30PM-05:00PM | 68-180 |
There will be 12 class sessions scheduled on January 6, 7, 8, 14, 15, 16, 21, 22, 27, 28, 29, 30.
11th of 12
Jason Sello - MLK Visiting Associate Professor of Biology
| Jan/30 | Thu | 03:30PM-05:00PM | 68-121 |
There will be 12 class sessions scheduled on January 6, 7, 8, 14, 15, 16, 21, 22, 27, 28, 29, 30.
Last class
Jason Sello - MLK Visiting Associate Professor of Biology
Error and Fraud in Chemical Research
Rick Danheiser, A C Cope Professor of Chemistry
| Jan/16 | Thu | 04:00PM-05:30PM | 6-120 |
Enrollment: Unlimited: No advance sign-up
Prereq: Introductory level organic chemistry
Case studies of error and fraud in chemical research.
Sponsor(s): Chemistry
Contact: Rick Danheiser, 18-298, 617-253-1842, danheisr@mit.edu
Get the most from your "omics" analysis: GeneGo MetaCore Software Training
Courtney Crummett, GeneGo Trainer
| Jan/22 | Wed | 03:00PM-05:00PM | 14N-132 DIRC |
Enrollment: Unlimited: Advance sign-up required
Sign-up by 01/22
Attend this IAP session and learn how to use GeneGo, a bioinforamtics software tool licensed by MIT Libraries. GeneGo provides a solution for using "omics" gene lists to generate and prioritize hypotheses with MetaCore. Learn how to work with different types of data (genomics, proteomics, metabolomics and interaction data) beginning with how to upload gene lists and expression data. Use GeneGo software to: upload, batch upload, store, share and check data properties and signal distribution; extract functional relevance by determining the most enriched processes across several ontologies; emphasize the role of expression data in your analysis; visually predict experimental results, associated disease and possible drug targets; and compare data sets and work with experiment intersections. Please register. Need a GeneGo Account? Email ask-bioinfo@mit.edu
Sponsor(s): Libraries, Biology
Contact: Courtney Crummett, 14S-M48, x4-8290, crummett@mit.edu
How to get the most from the Koch Institute Bioinformatics Support and Computational Resources
Charlie Whittaker, KI Bioinformatics and Computing Core Facility Research, Jingzhi Zhu, KI Bioinformatics and Computing Core Facility Researcher
| Jan/27 | Mon | 09:00AM-11:00AM | 14N-132 DIRC |
Enrollment: Limited: Advance sign-up required
Sign-up by 01/27
Limited to 40 participants
Prereq: This session is open to Researchers affiliated with Koch Ins
The Koch Institute Bioinformatics and Computing Core Facility provides researchers with support for various computational recourses. These resources include a Linux compute cluster, extensive data storage and a wide range of applications. Please sign up for this session if you are a researcher affiliated with the Koch Institute, MIT Biology Department, MIT Center for Environmental Health Sciences or MIT Biological Engineering and are interested in learning how to get the most from the support we provide. We will cover IT-related topics such as cluster usage and storage access as well as provide general examples of bioinformatics analytical pipelines.
Note: This session is open to Researchers affiliated with Koch Institute Member Laboratories, MIT Biology Department, MIT Center for Environmental Health Sciences or MIT Biological Engineering.
Sponsor(s): Biology, Biological Engineering, Libraries
Contact: Courtney Crummett, 14S-134, 617 324-8290, CRUMMETT@MIT.EDU
How to Photograph Birds
Frank Taylor, Senior Research Scientist (Physics/LNS), Emeritus
| Jan/10 | Fri | 11:00AM-12:00PM | 26-414 |
Enrollment: Unlimited: No advance sign-up
Prereq: None
Have you ever wanted to observe birds really closely? A pair of binoculars, or better still a spotting scope, will provide a good view only if the bird stays still, but what do birds look like when they fly, how are their feathers deployed? In this one hour talk I will discuss the challenge of photographing birds, describe equipment and technique and the pursuit of the (European) Common Swift (Apus apus).
Sponsor(s): Lab for Nuclear Science
Contact: Frank Taylor, 26-569, 617-253-7249, fet@mit.edu
Introduction to the FDA IND Process: Getting from bench to bedside
Claudia Mickelson, Deputy Dir. & Special Advisor to the VP for Rsrch, EHS
| Jan/29 | Wed | 10:00AM-12:00PM | 68-181 |
Enrollment: http://ehs.mit.edu/site/content/iap-course-registration
Limited to 35 participants
The process of translating laboratory discoveries into clinically relevant therapeutics takes a long time, costs a great deal of money, and had a high failure rate. This is partly due to the complex nature of the process and the FDA regulations and the fact that researchers are not familiar with the various steps in the process and what must be done at each step. This is a dynamic process in those issues and adverse events observed in past clinical trials are used to inform decisions about ongoing and new clinical trials. This class will give an overview of the steps, the requirements and submissions needed to obtain FDA permission to conduct a phase I clinical trial in the U.S. Examples from various different human gene therapy clinical trials will be discussed.
Sponsor(s): Environment, Health and Safety Office
Contact: Jessica Van, N52-496, 617 452-3233, JVAN@MIT.EDU
Joy of Clinical Medicine
Dr. Louis Kuchnir, MD-PhD, MIT '87 & Emily Brown, MIT '13
| Jan/31 | Fri | 07:00PM-08:00PM | 4-163 |
Enrollment: Unlimited: No advance sign-up
Back when doctors were among the wealthiest Americans, they could have retired early, but instead they tended to work until their own health failed. Lately, clinical medicine is cast as an unrewarding profession. Observers point to how "jackpot justice" is causing a malpractice crisis while cost-savings programs developed by managed care bureaucracies are blamed for destabilizing the doctor-patient relationship. Dr. Louis Kuchnir will inspire those of you interested in becoming clinicians by explaining how the rewards of medical practice are so enormous that they outweigh the indignities that dominate the headlines.
Ms. Emily Brown, who has been working at Kuchnir Dermatology as a patient care coordinator since graduating from MIT in 2013, will also describe her experience in a novel program where future physicians work for dermatologists in Massachusetts as they apply to medical school. The recruitment process to find Emily’s successor (for the 2014-2015 program) is currently underway, and a full description of the program is posted at kuchnirdermatology.com.
For more information and to register visit CareerBridge at https://www.myinterfase.com/mit/student/, click on the "Events" tab, and select "Info Session" from the "Category" drop-down menu.
Contact: Erin Scott, 12-185, 617-715-5328, scotte@mit.edu
Methods for analyzing neural data
Ethan Meyers, Postdoctoral Associate, BCS, MIBR, CBMM, Wasim Malik, Instructor in Anesthesia Harvard Medical School, MGH
Enrollment: Unlimited: No advance sign-up
Attendance: Participants welcome at individual sessions
This course will cover several methods that are useful for analyzing neural data including conventional statistics, mutual information, point process models and decoding analyses. The emphasis will be on explaining the basic mathematical intuitions behind these methods, and giving practical hands-on experience for how these methods can be applied to real data. The class will be divided into lectures that will explain different methods and into laboratory classes where students can analyze real data. Students are welcome to attend any lecture/lab sessions that they find useful. The examples used will focus on neural spiking activity but we will also discuss other types of signals including MEG signals, and local field potentials. Some familiarity with neuroscience and basic statistics will be useful. Please signup for the class here: http://tinyurl.com/k5cec6f
For more information see: http://web.mit.edu/emeyers/www/IAP_2014/
Sponsor(s): Brain and Cognitive Sciences
Contact: Ethan Meyers, 46-5155, 617 447-7814, EMEYERS@MIT.EDU
| Jan/21 | Tue | 03:00PM-04:00PM | 46-3189 |
We will cover classical statistics which is the most widely used method to analyze neural data, and also mutual information analyses.
Ethan Meyers - Postdoctoral Associate, BCS, MIBR, CBMM
| Jan/22 | Wed | 03:00PM-04:00PM | 46-5193, Bring a laptop |
We will have Matlab exercises where you can try out classical statistics and mutual information analyses on real data.
Ethan Meyers - Postdoctoral Associate, BCS, MIBR, CBMM
| Jan/23 | Thu | 03:00PM-04:00PM | 46-3189, Bring a laptop |
We will cover population decoding analyses and dimensionality reduction analyses
Ethan Meyers - Postdoctoral Associate, BCS, MIBR, CBMM
| Jan/23 | Thu | 04:00PM-05:00PM | 46-3189, Bring a laptop |
We will have Matlab exercises where you can try out population decoding and dimensionality reduction methods.
Ethan Meyers - Postdoctoral Associate, BCS, MIBR, CBMM
| Jan/28 | Tue | 03:00PM-04:00PM | TBA |
We will cover point process models for data analysis.
Wasim Malik - Instructor in Anesthesia Harvard Medical School, MGH
| Jan/29 | Wed | 03:00PM-04:00PM | TBA, Bring a laptop |
We will have Matlab exercises where you can try out point process models on real data.
Wasim Malik - Instructor in Anesthesia Harvard Medical School, MGH
Protocols and Methods: Recipes for research
Howard Silver
| Jan/16 | Thu | 12:00PM-01:00PM | 14N-132 (DIRC) |
Enrollment: Limited: Advance sign-up required
Sign-up by 01/16
Limited to 25 participants
Prereq: none
A couple hours in the Library can save you a couple of weeks in the lab. Don't waste your time reinventing the gelatin sponge-choriallantoic membrane assay. Improve your efficiency by learning strategies for finding published research protocols and methods. This session is a hands-on practicum that introduces attendees to resources that support bioscience bench research.
Please register for this session.
Sponsor(s): Libraries
Contact: Howard Silver, 14S-134, 617 253-9319, HSILVER@MIT.EDU
The Impact of Chemistry on Understanding Biology
Professor Matt Vander Heiden, Assistant Professor of Biology
Enrollment: Unlimited: No advance sign-up
Attendance: Participants welcome at individual sessions
Prereq: none
This series has speakers that have combined approaches and disciplines to study of chemistry and biology.
Sponsor(s): Biology
Contact: Prof. Matt Vander Heiden, 76-561, 617-715-4471, mvh@mit.edu
| Jan/07 | Tue | 04:00PM-05:00PM | 32-123 |
"Chemical Modulation of Chromatin Structure and Function"
Jay Bradner - Assistant Professor
| Jan/08 | Wed | 11:00AM-12:00PM | 76-156 |
"Chemical Genetics and the Genetics of Chemistry"
Jason Sello - Associate Professor, Dept of Chemistry, Brown
| Jan/14 | Tue | 11:00AM-12:00PM | 76-156 |
"Homeostasis: Controlling Metallation and Oxygen Sensitivity: Ribonucleotide Reductases as a Paradigm"
Joanne Stubbe - Novartis Professor of Chemistry; Professor of Biology
| Jan/22 | Wed | 10:00AM-11:00AM | 76-156 |
"New Insights Into Proteasome Function: From Protein Degradation to Cancer and Neurodegeneration"
Alfred Goldberg - Professor of Cell Biology
| Jan/31 | Fri | 11:00AM-12:00PM | Location TBD |
"Modulating Transcriptional Regulation Using Small Molecules"
Angela Koehler - Assistant Professor, Dept of Biological Engineering
| Feb/02 | Sun | 04:00PM-05:00PM | 76-156 |
"The Genetic Basis for Cancer Therapeutics"
Actual date of talk: Monday, February 3, 2014
William Sellers - Global Head of Oncology
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