MIT: Independent Activities Period: IAP

IAP 2016 Activities by Category - Life Sciences

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A Look Inside the Human Brain using Modern Imaging Technologies

Dimitrios Pantazis, Director of MEG Lab

Enrollment: Limited: Advance sign-up required
Limited to 30 participants
Attendance: Participants welcome at individual sessions

Modern imaging technologies at MIT and MGH provide exciting new ways to understand the structure and function of the human brain. We will provide guided tours of our imaging facilities and show how we use these tools to look inside the brain. Our recently installed MEG system, capable of measuring magnetic fields a billionth of the magnetic field of earth, can record the simultaneous firing of thousands of cortical neurons as they form dynamic networks.  Our MRI scanners provide high resolution images of the human brain as subjects perform a wide range of perceptual and cognitive tasks. Our PET scanners can identify and localize specific molecules in the brain, revealing pathologies that may underlie many different brain disorders. TMS is a noninvasive method that uses electromagnetic induction to create weak electric currents and cause depolarization or hyperpolarization in the neurons of the brain. NIRS uses infrared light to illuminate tissue and infer brain activity through the diffusion and scattering of this light. tCS is a neurostimulation technique that uses low current delivered to the brain using electrodes on the scalp. We will introduce these technologies, offer lab tours and demonstrate data collection, and discuss their contribution to neuroscience.

Contact: Dimitrios Pantazis, 46-5147, 617 324-6292, PANTAZIS@MIT.EDU


Seminar on Near Infrared Spectroscopy

Jan/20 Wed 02:00PM-03:00PM MIT bldg46, rm3015

Near Infrared Spectroscopy (NIRS) instrumentation, principles of light scattering and absorption, imaging of oxygenated hemoglobin, NIRS applications.

Juliette Selb - Instructor


Seminar on Magnetic Resonance Imaging

Jan/20 Wed 03:00PM-04:30PM MIT bldg46, rm3015

Topics include MRI instrumentation, magnetic fields, safety, functional imaging with BOLD response, diffusion imaging, and others.

Anastasia Yendiki - Assistant Professor, Atsushi Takahashi - Assistant Director, MR Physicist


A tour at the MRI Lab

Jan/20 Wed 04:30PM-05:30PM MIT bldg46, rm1171

A tour at the MRI lab. Demo scan (finger tapping) and data analysis.

MRI Lab: http://mcgovern.mit.edu/technology/martinos-imaging-center/technical-resources

Steven P Shannon - Operations Manager and MR Research Technologist, Sheeba Arnold Anteraper - MR Programmer, Atsushi Takahashi - Assistant Director, MR Physicist


Seminar on Positron Emission Tomography

Jan/21 Thu 02:00PM-03:00PM MIT bldg46, rm3015

Seminar on Positron Emission Technology. Introduction to PET technology and scanners at MGH; applications in tumor detection; brain metabolic activity; gene expression; neurological diseases, such as Alzheimer¿s and Parkinson's; pharmacology etc.

Quanzheng Li - Assistant Professor


Seminar on Magnetoencephalography

Jan/21 Thu 03:00PM-04:00PM MIT bldg46, rm3015

Electrophysiological basis of MEG signals; instrumentation; modeling; cortical rhythms; brain networks; combining MEG with fMRI, studying the human visual system. 

Dimitrios Pantazis - Director of MEG Lab


A tour at the MEG Lab

Jan/21 Thu 04:00PM-05:00PM MIT bldg46, rm1147

A tour at the MEG Lab, demo scan and data analysis of an MEG experiment

MEG Lab: http://mcgovern.mit.edu/technology/meg-lab

Dimitrios Pantazis - Director of MEG Lab, Yasaman Bagherzadeh - Postdoctoral Affiliate


Seminar and demo on TMS

Jan/22 Fri 03:00PM-05:00PM MGH CNY 149 - A, Location in Charlestown!

Use of Transcranial Magnetic Stimulation to depolarize and hyperpolarize neurons of the brain, applications to treat depression and examine basic mechanisms of post-traumatic stress disorder and anxiety, among others. The seminar will include a demo of the MGH TMS system!

Aapo Nummenmaa - Instructor


Seminar on Transcranial Current Stim.

Jan/22 Fri Time TBD Seminar Cancelled

Introduction on transcranial current stimulation. Differences and applications of direct- and alternating-current stimulation (tDCS and tACS), instrumentation, modulation of ongoing rhythmic brain activity.

Dimitrios Pantazis - Director of MEG Lab


Are You In or Out? An Overview of the Material Transfer Process at MIT

Danielle Byrdsong, MTA Associate Officer

Jan/21 Thu 01:30PM-03:00PM 66-156

Enrollment: Unlimited: Advance sign-up required
Sign-up by 01/21

The transfer of materials into and out of MIT is steadily increasing each year. Moreover, the providers and recipients for these materials are diversifying.

Material Transfer Agreements (MTAs) are legal contracts that ensure all parties are permitted to send and receive biological materials, chemical compounds, and other materials. MTAs protect MIT’s intellectual property and freedom to publish, and MTAs record the terms and conditions for the use of the materials.

Come and join Danielle Byrdsongi to learn about MIT's Material Transfer process. Gain a better understanding of MTAs, MIT’s procedures and policies for MTAs, and how to get your materials expeditiously.

Please register by emailing kmkhalil@mit.edu   

Sponsor(s): Technology Licensing Office
Contact: Katrina Khalil-Iannetti, NE18-501, 617 253-6966, kmkhalil@mit.edu


Bioinformatics for Beginners 2016

Howard Silver, Biological Engineering Librarian

Jan/12 Tue 03:30PM-05:00PM 14N-132
Jan/15 Fri 10:30AM-12:00PM 14N-132

Enrollment: Limited: Advance sign-up required
Sign-up by 01/15
Limited to 30 participants
Attendance: Repeating event, particpants welcome at any session

The National Center for Biotechnology Information (NCBI) Entrez family of databases is the foundation of knowledge for molecular level bioscience research. Class attendees will learn about the organization and interconnectedness of NCBI databases while focusing on several specific databases. The session is a hands-on practicum and an excellent starting point for people who are new to or curious about bioinformatics research tools. This session is offered twice covering the same material; participants welcome at either session. 

Register:  Tuesday, January 12, 3:30 - 5 pm

Register:  Friday, January 15, 10:30 - 12 pm

 

Sponsor(s): Libraries, Biology
Contact: Howard Silver, 14S-134, 617 253-9319, HSILVER@MIT.EDU


Biotech Business Information for Engineers

Courtney Crummett, Biosciences Librarian

Jan/20 Wed 04:00PM-05:00PM 14N-132 (DIRC)

Enrollment: Limited: Advance sign-up required


It's not brain surgery...it's market research. This session will introduce scientists and engineers to business information resources that cover biotechnology industries and markets. We will use realistic examples and hands-on exercises with key resources to demonstrate how to match your ideas and discoveries with the opportunities and realities of the marketplace. Please register for this event.

 

 

Sponsor(s): Libraries, Biology
Contact: Courtney Crummett, 14S-134, 617 324-8290, CRUMMETT@MIT.EDU


Get the most from your "omics" analysis: GeneGo MetaCore Software Training

Courtney Crummett, GeneGo Trainer

Jan/26 Tue 04:00PM-06:00PM 14N-132 (DIRC)

Enrollment: Limited: Advance sign-up required
Sign-up by 01/21
Limited to 30 participants

Attend this IAP session and learn how to use MetaCore, a bioinformatics software tool licensed by MIT Libraries. MetaCore provides a solution for using "omics" gene lists to generate and prioritize hypotheses for novel biomarkers, targets, and mechanisms of action. Learn how to work with different types of data such as genomics, proteomics, metabolomics and interaction data.  Use this tool to  upload, batch upload, store, share and check data properties and signal distribution; extract functional relevance by determining the most enriched processes across several ontologies; emphasize the role of expression data in your analysis; visually predict experimental results, associated disease and possible drug targets; and compare data sets and work with experiment intersections. A new feature, Key Pathway Advisor (KPA) which can be used to predict upstream regulators from differentially expressed genes and help identify key pathways that they participate in with be demoed.  Please register. Need a GeneGo Account? Email ask-bioinfo@mit.edu

Sponsor(s): Libraries, Biology
Contact: Courtney Crummett, 14S-M48, x4-8290, crummett@mit.edu


Neuropsychiatry in Translation: The Next Generation

Maria Dauvermann, Postdoctoral Associate

Enrollment: Limited: First come, first served (no advance sign-up)
Limited to 15 participants
Attendance: Participants must attend all sessions
Prereq: None

It has been estimated that 18.5% of adults in the U.S. had a psychiatric disorder in 2013. The treatment success rates with traditional pharmacology among every psychiatric disorder are very low. This goes hand-in-hand with the limitations of currently available diagnostic and prognostic tools.
We know that the brain plays a major role in the development of these disorders. Therefore, technologies for potential diagnosis and treatment options have been developed that aim to change the function of the brain. These new technologies for diagnosis and invention approaches are in development but require thorough translational research before they can be safely used in patients.
The aim of the course is to teach about technologies and intervention approaches that move beyond pharmacology as the sole treatment option. Over the course of four sessions, you will learn how brain scientists from different disciplines (biologists, chemists, physicists, psychologists, informaticians, engineers) invent and develop techniques in multiple translational steps as diagnosis and treatment options for patients. You will design and present your own translational study at the end of the course.

Session 1: Currently available techniques and treatment options

Session 2: Promising technologies for diagnosis and treatment options in humans, monkeys and rodents

Session 3: Practical translational research steps across species

Session 4: Design, presentation and discussion of translational studies

Sponsor(s): Brain and Cognitive Sciences
Contact: Maria Dauvermann, 46-2171, 617-324-3599, mariad@mit.edu


Jan/07 Thu 01:00PM-03:00PM 46-4062
Jan/08 Fri 01:00PM-03:00PM 46-4062
Jan/14 Thu 01:00PM-03:00PM 46-4062
Jan/15 Fri 01:00PM-03:00PM 46-4062

Maria Dauvermann - Postdoctoral Associate


Pre-med volunteering: spice up your resume and do something meaningful (and maybe even earn a paycheck!)

Alison Hynd, Director for Programs, Chiara Magini, Community Employment Administrator, Sarah Bouchard, Community Engagement Administrator, Meaghan Shea, Prehealth Advisor

Jan/21 Thu 02:00PM-03:00PM 4-149

Enrollment: Limited: Advance sign-up required
Sign-up by 01/20

Are you pre-med or considering a health career?

Do you want to do something meaningful to fulfill the med school application service requirement?

Are you interested in funded community service options?

Do you worry that your current activities won't stand out in a sea of similar applications?

Then this session is for you!

Staff from the Priscilla King Gray Public Service Center and Prehealth Advising will present options for meaningful health-related community service activities in the Boston area and beyond. You'll learn about cohort-based programs, individual volunteering resources, funding possibilities, and get help identifying the opportunity that works for you.

And we want to learn from you! Come ready to tell us what you want to do and how we can help.

Sponsor(s): Priscilla King Gray Public Service Center, Global Education and Career Development
Contact: Alison Hynd, W20-549, 617 258-0691, HYND@MIT.EDU


Protocols and Methods: Recipes for research

Howard Silver

Jan/19 Tue 12:00PM-01:00PM 14N-132

Enrollment: Limited: Advance sign-up required
Sign-up by 01/15
Limited to 30 participants
Prereq: none

A couple hours in the Library can save you a couple of weeks in the lab. Need to know how to do Optogenetic manipulation of neural activity in freely moving Caenorhabditis elegans? Improve your efficiency by learning strategies for finding published research protocols and methods. This session is a hands-on practicum that introduces attendees to resources that support bioscience bench research.

Please register for this session.

Sponsor(s): Libraries
Contact: Howard Silver, 14S-134, 617 253-9319, HSILVER@MIT.EDU


(CANCELED) Reproducibility in Synthetic Organic Chemistry

Rick Danheiser, A C Cope Professor of Chemistry

Jan/28 Thu 04:00PM-05:30PM 6-120

Enrollment: Unlimited: No advance sign-up

A fundamental principle in the field of synthetic organic chemistry states that a synthetic chemist skilled in the art should be able to repeat a synthetic transformation with the same results as those described in published work from another laboratory. Unfortunately, all too often this is not the case. Why do many procedures prove not to be reproducible? Why do even experienced researchers encounter problems when attempting to repeat reactions described in the literature? This talk will focus on the most common causes of problems involving reproducibility in organic synthesis. The specific examples discussed will be based on experiences from my own laboratory, examples taken from the literature, and examples from procedures submitted to Organic Syntheses that I am familiar with from my service as Editor in Chief of that journal. 

Sponsor(s): Chemistry
Contact: Rick Danheiser, 18-298, 617 253-1842, danheisr@mit.edu


The Doctor Is In: Medical Information at MIT Libraries

Courtney Crummett, Biosciences Librarian

Jan/22 Fri 11:00AM-12:00PM 14N-132 (DIRC)

Enrollment: Limited: Advance sign-up required

We may not have a medical school, but the Libraries is full of medical information to support your research. Need to find an efficacy study on a drug or treatment protocol? Need to understand the physiology of the nervous systems? Need to better understand the screening and prevention of a particular disease or disorder? This hands-on workshop will demonstrate how our collections can help you find these answers. Registration required. 

Sponsor(s): Biology, Libraries
Contact: Courtney Crummett, 14S-134, 617 324-8290, CRUMMETT@MIT.EDU


The Next Step in Academic Science

Prof. Piyush Gupta, Assistant Professor of Biology, Member, Whitehead Institute

Enrollment: Unlimited: No advance sign-up
Attendance: Participants welcome at individual sessions

MIT Biology presents a selection of talks on the practice of science, naviagating academia, and balancing it all with a life outside the lab.

Sponsor(s): Biology
Contact: Piyush Gupta, WI-661C, 617-324-0086, pgupta@wi.mit.edu


Post-doc positions in Academia & Industry

Jan/14 Thu 01:30PM-03:00PM 68-181

The next step after graduate school - a post doc. It's not as intimidating as you think. What should you look for in a lab? Can you switch fields?How do you send out the first letter? Come meet post docs from academia and industry, and learn about how to get a post doc position!

Zainab Jagani - Industry post doc, Jill Goldstein - Academic post doc, Sandhya Sanduja - Head of post doc association


The Path to Faculty

Jan/19 Tue 01:30PM-03:00PM 68-181

Are you planning to apply for an academic job?  Are you considering a more teaching oriented career? Find out about career options at primarily undergraduate institutions, where professors dedicate much of their time to teaching yet also manage their own research programs and mentor students. Learn about this from a panel of faculty members at teaching colleges.

 

Joanne C. Pratt - Associate Professor of Biological Sciences, Caroline Goutte - Professor of Biology, Jason Pellettieri - Associate Professor of Biology, Vanja Klepac-Ceraj - Assistant Professor of Biological Sciences


Careers at Research Institutions

Jan/20 Wed 01:30PM-03:00PM 68-181

For those considering careers within academia, this panel will bring together speakers from a variety of research-oriented institutions.

 

 

Jeffrey Chuang - Associate Professor, Piyush Gupta - Assistant Professor of Biology, Megan C. King - Associate Professo of Cell Biology, Sallie Smith Schneider - DirectorBiospecimen Resource & Molecular Analysis Facility


The Science and Engineering of Intelligence: A bridge across Vassar Street

Andrea Tacchetti

Jan/15 Fri 10:00AM-05:00PM 46-3002

Enrollment: Unlimited: No advance sign-up
Prereq: None

Neuroscience has made huge advances in the last few years. We now know more about how the brain works than we have ever known before. Likewise, Computer Science and Artificial Intelligence have made enormous steps forward and have become part of our every-day lives. The interaction between Neuroscience and Computer Science has inspired most recent advances in Artificial Intelligence and this interaction has become a critical stepping stone for the understanding of intelligence. We assembled a stellar list of speakers at the intersection of Neuroscience and AI from both sides of Vassar Street who will give an account of how this multi-disciplinary interaction affects their work. The tentative list of speakers includes:

Professor Ed Boyden
Professor Tomaso Poggio
Professor Nancy Kanwisher
Professor Feng Zhang
Professor Bill Freeman
Professor Joshua Tenenbaum

Schedule and other information about the event can be found here: http://cbmm.mit.edu/science-engineering-vassar

 

Sponsor(s): Brain and Cognitive Sciences
Contact: Andrea, Tacchetti, N/A, atacchet@MIT.EDU


Tutorial Series in Computational Topics related to Brain and Cognitive Sciences

Emily Mackevicius

Enrollment: Unlimited: Advance sign-up required
Attendance: Participants welcome at individual sessions
Prereq: Geared towards BCS grad students & postdocs, others welcome

Each tutorial will consist of a short lecture, and then 'office hours' time to work through practice problems and discuss problems people want help with in their own research. The goal is to get people past the initial learning curve in particular computational topics relevant to BCS, and get people from across the department talking about common computational methods. Food will be provided.

Please sign up for tutorials here: https://docs.google.com/forms/d/11yK-Xqc_1UU29qWAuQLqZjtMXyidLohxGVUIO9MjUjQ/viewform

Materials will be posted here (Currently this site has material for previous BCS computational tutorials.  If you sign up, I'll email you when current materials are posted.): https://stellar.mit.edu/S/project/bcs-comp-tut/index.html

Sponsor(s): Brain and Cognitive Sciences
Contact: Emily Mackevicius, ELM@MIT.EDU


Cluster computing and OpenMind

Jan/12 Tue 04:00PM-06:00PM 46-3310

Taught by: Satrajit Ghosh and Evan Remington


Dimensionality Reduction I

Jan/19 Tue 04:00PM-06:00PM 46-3310

Taught by: Emily Mackevicius and Greg Ciccarelli


Dimensionality Reduction II

Jan/21 Thu 04:00PM-06:00PM 46-3310

Taught by: Sam Norman-Haignere


Dynamical Systems

Jan/22 Fri 02:00PM-04:00PM 46-3310

Taught by: Seth Egger