MIT: Independent Activities Period: IAP

IAP 2017 Activities by Category - Life Sciences

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A Look Inside the Human Brain using Modern Imaging Technologies

Dimitrios Pantazis, Director of MEG Lab

Enrollment: Limited: Advance sign-up required
Limited to 30 participants
Attendance: Participants welcome at individual sessions

Modern imaging technologies at MIT and MGH provide exciting new ways to understand the structure and function of the human brain. We will provide guided tours of our imaging facilities and show how we use these tools to look inside the brain. Our magnetoencephalography (MEG) system, capable of measuring magnetic fields a billionth of the magnetic field of earth, can record the simultaneous firing of thousands of cortical neurons as they form dynamic networks.  Our magnetic resonance imaging (MRI) scanners provide high resolution images of the human brain as subjects perform a wide range of perceptual and cognitive tasks. Our positron emission tomography (PET) scanners can identify and localize specific molecules in the brain, revealing pathologies that may underlie many different brain disorders. Transcranial magnetic stimulation (TMS) is a noninvasive method that uses electromagnetic induction to create weak electric currents and cause depolarization or hyperpolarization in the neurons of the brain. Near infrared spectroscopy (NIRS) uses infrared light to illuminate tissue and infer brain activity through the diffusion and scattering of this light. We will introduce these technologies, offer lab tours and demonstrate data collection, and discuss their contribution to neuroscience.

Contact: Dimitrios Pantazis, 46-5147, 617 324-6292, PANTAZIS@MIT.EDU


Seminar on Magnetoencephalography

Jan/18 Wed 02:00PM-03:30PM 46-3015

Electrophysiological basis of MEG signals; instrumentation; modeling; cortical rhythms; brain networks; combining MEG with fMRI, studying the human visual system. 

Dimitrios Pantazis - Director of MEG Lab, Dimitris Pinotsis - Visiting Scientist, Yalda Mohsenzadeh - Postdoctoral Associate


A tour at the MEG Lab

Jan/18 Wed 03:30PM-04:30PM 46-1147

A tour at the MEG Lab, demo scan and data analysis of an MEG experiment

MEG Lab: http://mcgovern.mit.edu/technology/meg-lab

Dimitrios Pantazis - Director of MEG Lab, Yalda Mohsenzadeh - Postdoctoral Associate


Seminar on Positron Emission Tomography

Jan/19 Thu 02:00PM-03:00PM 46-3015

Seminar on Positron Emission Technology. Introduction to PET technology and scanners at MGH; applications in tumor detection; brain metabolic activity; gene expression; neurological diseases, such as Alzheimer¿s and Parkinson's; pharmacology etc.

Quanzheng Li - Assistant Professor


Seminar on Near Infrared Spectroscopy

Jan/19 Thu 03:00PM-04:00PM 46-3015

Near Infrared Spectroscopy (NIRS) instrumentation, principles of light scattering and absorption, imaging of oxygenated hemoglobin, NIRS applications.

Juliette Selb - Instructor


Seminar on Transcranial Magnetic Stim.

Jan/19 Thu 04:00PM-05:00PM 46-3015

Use of Transcranial Magnetic Stimulation to depolarize and hyperpolarize neurons of the brain, applications to treat depression and examine basic mechanisms of post-traumatic stress disorder and anxiety, among others. The seminar will include a demo of the MGH TMS system!

Aapo Nummenmaa - Instructor


Seminar on Magnetic Resonance Imaging

Jan/20 Fri 03:00PM-04:30PM 46-3015

Topics include MRI instrumentation, magnetic fields, safety, functional imaging with BOLD response, diffusion imaging, and others.

Anastasia Yendiki - Assistant Professor, Sheeba Arnold Anteraper - MR Programmer


A tour at the MRI Lab

Jan/20 Fri 04:30PM-05:30PM 46-1171

A tour at the MRI lab. Demo scan (finger tapping) and data analysis.

MRI Lab: http://mcgovern.mit.edu/technology/martinos-imaging-center/technical-resources

Steven P Shannon - Operations Manager and MR Research Technologist, Sheeba Arnold Anteraper - MR Programmer


Are You In or Out? An Overview of the Material Transfer Process at MIT

Danielle Byrdsong, MTA Associate Officer, Siri Nilsson, Technology Licensing Officer, Contracts

Jan/31 Tue 02:00PM-03:00PM 56-169

Enrollment: Unlimited: Advance sign-up required
Sign-up by 01/31

The transfer of materials into and out of MIT is steadily increasing each year. Moreover, the providers and recipients for these materials are diversifying.

Material Transfer Agreements (MTAs) are legal contracts that ensure all parties are permitted to send and receive biological materials, chemical compounds, and other materials. MTAs protect MIT’s intellectual property and freedom to publish, and MTAs record the terms and conditions for the use of the materials.

Come and join Danielle Byrdsong and Siri Nilsson to learn about MIT's Material Transfer process. Gain a better understanding of MTAs, MIT’s procedures and policies for MTAs, and how to get your materials expeditiously.

Please register by emailing kmkhalil@mit.edu   

Sponsor(s): Technology Licensing Office
Contact: Katrina Khalil, NE18-501, 617 253-6966, kmkhalil@mit.edu


Clinical Imaging Informatics: Radiology in 2020

Randy Gollub, HST Affiliated - Associate Professor of Psychiatry, MGH

Enrollment: Limited: Advance sign-up required
Sign-up by 12/19
Limited to 40 participants
Attendance: Participants welcome at individual sessions

https://hst.mit.edu/IAP2017_Clinical_Imaging_Informatics

This course offers an in depth examination of the complete clinical imaging workflow from the perspective of the enabling technologies, many of which are being developed at MIT and collaborating academic healthcare centers. In hands-on sessions, participants will have the opportunity to develop cutting edge medical image visualization software tools and to explore data analysis and machine learning using quantitative metrics extracted from medical images and associated free text or structured meta-data.

As part of the course participants will begin to learn how to:

Goal of this educational effort is to catalyze the development of clinical imaging informatics infrastructure to help turn the wealth of raw medical images and linked health records into actionable medical knowledge: (1) by attracting new minds to pursue this career path; (2) by stimulating new collaborations between technology leaders and clinical translational investigators; and (3) by inspiring new applications of existing technologies.

Sponsor(s): Institute for Medical Engineering & Science, Health Sciences
Contact: Randy Gollub, rgollub@partners.org


Introduction to the Clinical Informatics

Jan/10 Tue 03:00PM-07:00PM E25-119, Bring a laptop

Visit https://hst.mit.edu/IAP2017_Clinical_Imaging_Informatics for session details, etc.

You are welcome to attend individual sessions, but you will get the most out of the course by attending all 4 sessions as they build upon each other.

Randy Gollub - HST Affiliated - Associate Professor of Psychiatry, MGH


Attributes of Medical Image Data

Jan/17 Tue 03:00PM-07:00PM E25-119, Bring a laptop

Visit https://hst.mit.edu/IAP2017_Clinical_Imaging_Informatics for session details, etc.

You are welcome to attend individual sessions, but you will get the most out of the course by attending all 4 sessions as they build upon each other.

Randy Gollub - HST Affiliated - Associate Professor of Psychiatry, MGH


Clinical Annotation

Jan/24 Tue 03:00PM-07:00PM E25-119, Bring a laptop

Visit https://hst.mit.edu/IAP2017_Clinical_Imaging_Informatics for session details, etc.

You are welcome to attend individual sessions, but you will get the most out of the course by attending all 4 sessions as they build upon each other.

Randy Gollub - HST Affiliated - Associate Professor of Psychiatry, MGH


Machine learning in medical imaging

Jan/31 Tue 03:00PM-07:00PM E25-119, Bring a laptop

Visit https://hst.mit.edu/IAP2017_Clinical_Imaging_Informatics for session details, etc.

You are welcome to attend individual sessions, but you will get the most out of the course by attending all 4 sessions as they build upon each other.

Randy Gollub - HST Affiliated - Associate Professor of Psychiatry, MGH


DIY Medical Technology Construction Kits

Jose Gomez-Marquez, Little Devices Lab

Jan/10 Tue 09:30AM-03:30PM N52-373G

Enrollment: Limited: Advance sign-up required

Short Hand-on Seminar on DIY Medical Technology

Build medical device kits to empower patients and clinicians to make novel health devices.

What happens when everyone can make their own medical device? What are the drivers of how to democratize the basics of human health technology? The basics of DIY Medical Device Design and its implications are discussed in a series of hands-on activities and discussions to cover topics such as 

- (Re) fabrication of medical technology

- The pharmacies in our garages

- The EpiPen vs. The Nerf Gun and what we can do about it

- How mom's can design and make their own Zika tests

- The future of patient data if we make it ours

- A look at how a hospital makerspace operates

- The MakerNurse program

 

The disparities in affordable healthcare technology are a growing part of increasing healthcare costs globally. This course aims to teach affordable prototyping and design strategies for health technology and medicine that can be applied to improve patient care in a variety of settings: both low-income and high-income economies, at patients' homes and in hospitals. 

This one day seminar serves an an introduction to HST S.47 MakerLab, a two-week hands on sister course also offered during IAP.

For more information visit http://makerlab.mit.edu/ 

E-mail us: littledevices@mit.edu

 

Course Director(s):Lee GehrkeJose Gomez-MarquezAnna Young

 

Time: January 10th, 9:30am to 3pm

 

Location: N52-391

 

 

 

Sponsor(s): Institute for Medical Engineering & Science
Contact: Jose Gomez-Marquez, N52-373G, 617 674-7516, littledevices@mit.edu


Get the most from your "omics" analysis: GeneGo MetaCore Software Training

GeneGo Trainer, Courtney Crummett

Jan/12 Thu 10:00AM-12:00PM 14N-132 DIRC, bring your laptop

Enrollment: Limited: Advance sign-up required
Sign-up by 01/11

Attend this IAP session and learn how to use MetaCore, a bioinformatics software tool licensed by MIT Libraries. MetaCore provides a solution for using "omics" gene lists to generate and prioritize hypotheses for novel biomarkers, targets, and mechanisms of action. Learn how to work with different types of data such as genomics, proteomics, metabolomics and interaction data.  Use this tool to  upload, batch upload, store, share and check data properties and signal distribution; extract functional relevance by determining the most enriched processes across several ontologies; emphasize the role of expression data in your analysis; visually predict experimental results, associated disease and possible drug targets; and compare data sets and work with experiment intersections. A new feature, Key Pathway Advisor (KPA) which can be used to predict upstream regulators from differentially expressed genes and help identify key pathways that they participate in with be demonstrated.

Please register here: http://libcal.mit.edu/event/3004139

Sponsor(s): Libraries, Biology
Contact: Courtney Crummett, 14S-134, 617 324-8290, CRUMMETT@MIT.EDU


Introduction to Astrobiology

Roger Summons, Schlumberger Professor of Geobiology, Christopher Carr, Research Scientist, Alexandra Pontefract, Postdoctoral Associate

Enrollment: Email Alexandra Pontefract (apontefr@mit.edu) to sign-up.
Limited to 25 participants
Attendance: Participants welcome at individual sessions
Prereq: A knowledge of Biology and/or Geology would be an asset.

Have you always wondered what Astrobiology is, and what Astrobiologists do? Are you interested in the search for life beyond the Earth?

Come join us for two weeks as we explore the breadth of topics related to Astrobiology, from the origins of life here on Earth, to the habitability of other bodies in our solar system and beyond. Through this course you will gain an appreciation of the multi-disciplinary nature of planetary science research, and gain a basic understanding of the knowledge and instrumentation that goes into making a planetary exploration mission for life detection. 

This course will feature a series of lectures from MIT and Brown University Planetary scientists and Astrobiologists, along with lab demonstrations and group discussions.

Sponsor(s): Earth, Atmospheric and Planetary Sciences
Contact: Alexandra Pontefract, 54-511, apontefr@MIT.EDU


Introduction to Astrobiology

Jan/23 Mon 09:00AM-12:00PM 54-915

Lecture followed by a discussion on: Learning how to read a scientific article.

Alexandra Pontefract - Postdoctoral Associate


The History of Life on Earth I

Jan/24 Tue 09:00AM-12:00PM 54-915

Lecture followed by an opportunity to view some fossils and a tour of the Isotope Lab.

Roger Summons - Schlumberger Professor of Geobiology


The History of Life on Earth II

Jan/25 Wed 09:00AM-12:00PM 54-915

Lecture followed by a discussion on top-down phylogenomic reconstructions of deep ancestral life.

Greg Fournier - Cecil & Ida Green Assistant Professor of Geobiology


Extremophiles

Jan/26 Thu 09:00AM-12:00PM 54-915

Lecture followed by a discussion on Extremophilic Organisms.

Heather Throckmorton - Postdoctoral Associate


Habitable Environments Beyond Earth-Mars

Jan/27 Fri 09:00AM-12:00PM 54-915

Lecture followed by a demonstration of relevant technology.

Jack Mustard - Professor, Brown University


Habit. Envir. Beyond Earth-Ocean Worlds

Jan/30 Mon 09:00AM-12:00PM 54-915

Lecture followed by a lab on planetary datasets.

Jason Soderblom - Research Scientist


Life Detection and Instrumentation

Jan/31 Tue 09:00AM-12:00PM 54-915

Lecture followed by a demonstration of nanopore sequencing.

Christopher Carr - Research Scientist


Exoplanets

Feb/01 Wed 09:00AM-12:00PM 54-915

Lecture followed by an online Exoplanet lab.

Jennifer Burt - Postdoctoral Fellow


Introduction to neuron population recording methods

Keji Li, Postdoctoral Fellow, Murat Yildirim, Postdotoral Associate

Enrollment: Unlimited: Advance sign-up required
Sign-up by 01/07
Attendance: Participants welcome at individual sessions
Prereq: Basic Knowledge in linear algebra, Fourier transformation, a

This short course is designed to briefly introduce major invasive and noninvasive neuron recording methods used in neuroscience research today. The various methods for recording of neuron population activity are essential in modern neuroscience as they provide a vital technique in the exploration of: 1) functional role of brain areas; 2) role of specific cells types in local circuits; 3) neural encoding of sensory input or decision; 4) formation of memory and learned skill; 5) other uncharted territory in neuroscience. We target senior undergraduate and beginning graduate students, in the hope that this course will aid in their choice of future field of study and research.

We plan to have an overview of the major methods, then for each method the following topics will be discussed:

1)    theories behind the measurement

2)    implementation and important parameters

3)    analysis of the resulting data

4)    advantages and disadvantages of the method

5)    specific considerations when using the data

6)    notable uses of the method

Sponsor(s): Brain and Cognitive Sciences
Contact: Keji Li, Bldg 46, (617) 253-8785, kejili@mit.edu


Session 1

Jan/18 Wed 01:00PM-05:00PM 46-3189
Jan/19 Thu 01:00PM-05:00PM 46-3189

Session 1:

Optical imaging of intrinsic signal; wide field fluorescent imaging; extracellular electrode recording; their experiment design and data analysis using visual areas as example

Session 2:

Principles and applications of fluorescent imaging; one-photon imaging, confocal imaging, two-photon imaging; three-photon imaging; head-mounted fluorescent imaging; system design and analysis of their data


Introduction to sterile technique on the bench and biosafety cabinet

Lorena Altamirano, Biosafety Officer, EHS

Enrollment: Limited: Advance sign-up required
Sign-up by 01/06
Limited to 10 participants
Attendance: Participants must attend all sessions

Sterile or aseptic technique forms the basis of microbiology and tissue culturing method to prevent contamination of samples and safeguard people. This course is intended as an introduction to the theory and practice of sterile technique. This course would focus on sterile technique at the bench (basic bacteriology) as well as using a biological safety cabinet (BSC) for basic cell/tissue culturing.

Target audience: The course is intended for people from non-traditional biological sciences backgrounds such as engineering, physics, arts, architecture, etc.

Prereq: None; no biological experience is needed.

Registration: http://ehs.mit.edu/site/content/iap-course-registration

Sponsor(s): Environment, Health and Safety Office, Biology
Contact: Lorena Altamirano, 617-253-3844, lorealta@mit.edu


Lecture

Jan/10 Tue 10:00AM-12:00PM N52-496, Conference Room A

Lecture on principles and practices, equipment basics, materials and methods and protocol review.

Lorena Altamirano - Biosafety Officer, EHS


Laboratory Practice

Jan/11 Wed 10:00AM-12:00PM 68-088
Jan/12 Thu 10:00AM-12:00PM 68-082
Jan/13 Fri 10:00AM-12:00PM 68-088

Laboratory practices, equipment, protocol application and biosafety. Discussion and troubleshooting.

Must attend all lab pratice dates.

Lorena Altamirano - Biosafety Officer, EHS


Physics and Chemistry of Porous Materials and Its Energy Applications

Sungwoo Yang, Research scientist

Enrollment: Unlimited: Advance sign-up required
Sign-up by 01/27
Attendance: Participants welcome at individual sessions

Chemistry is a key to controlling the structure of a material, which ultimately determines the way that various carriers, such as photons, phonons, electrons, ions and molecules, propagate through materials. In this class, I will show how understanding the underlying physics and chemistry of porous materials can unlock a variety of sustainable energy applications including thermal energy storage, water harvesting from air, and solar-thermal energy conversion. The focus of this class is on three emerging porous materials: 1) metal organic frameworks (MOFs), 2) 3-dimensional graphene (3dGR), and 3) aerogels.  

By combining MOFs and 3dGR, we have demonstrated high thermal energy density (495 Wh kg-1 and 218 Wh L) at the component level. Furthermore, we demonstrated that by optimizing a water harvesting device with MOFs, ~2.8 L kg-1 at a relative humidity of 20% can be obtained – addressing the increasing problem of water scarcity.

Finally, the chemistry and physics of aerogels will be discussed. This thermally insulating and optically transparent aerogel has great promise for solar-thermal conversion applications. We demonstrated tempurates of 240 °C under un-concentrated solar illumination in ambient conditions, which can replace conventional heat systems based on natural gas combustion.

I will conclude by sharing future outlook about the critical role that chemistry and mechncial engineering inter-play for developing advanced materials for sustainable energy conversion. 

Sponsor(s): Mechanical Engineering
Contact: Sungwoo Yang, 7-034, 919 724-0662, SWYANG@MIT.EDU


Feb/02 Thu 10:00AM-11:00AM 7-034B
Feb/03 Fri 10:00AM-11:00AM 7-034B

Sungwoo Yang - Research scientist


Protocols and Methods: Recipes for research

Howard Silver

Jan/19 Thu 12:00PM-01:00PM 14N-132

Enrollment: Limited: Advance sign-up required
Sign-up by 01/19
Limited to 30 participants
Prereq: none

A couple hours with the Libraries' protocols and methods resources can save you a couple of weeks in the lab. Need to know how to do Optogenetic manipulation of neural activity in freely moving Caenorhabditis elegans? Improve your efficiency by learning strategies for finding published research protocols and methods. This session is a hands-on practicum that introduces attendees to resources that support bioscience bench research.

Please register for this session.

Sponsor(s): Libraries
Contact: Howard Silver, 14S-134, 617 253-9319, HSILVER@MIT.EDU


Quantitative Biology

Enrollment: Limited: First come, first served (no advance sign-up)
Attendance: Participants welcome at individual sessions

Seminar series with 3 guest lecturers and 3 talks.

Sponsor(s): Biology
Contact: Adam Martin, 68-459, 617-324-0074, acmartin@mit.edu


Precision & Plasticity

Jan/18 Wed 11:00AM-12:00PM McGovern Auditorium, in Whitehead Institute, 9 Cambridge Center

1st talk in the series

"Precision and Plasticity in Animal Transcription"

Angela DePace - Associate Professor, Department of Systems Biology


On Growth and Form

Jan/23 Mon 11:00AM-12:00PM McGovern Auditorium, in Whitehead Institute, 9 Cambridge Center

2nd talk in the series.

"On Growth and Form"

L. Mahadevan - de Valpine Prof of Applied Mathematics, Prof of Organismic &


Quantitatve Analysis

Jan/30 Mon 11:00AM-12:00PM McGover Auditorium, in Whitehead Institute, 9 Cambridge Center

3 talk in the series.

"Quantitative Analysis of the Molecular Mechanisms of Cytokinesis"

Thomas Pollard - Sterling Prof of Molecular, Cellular & Developmental Biology


Space Frontiers Lecture Series

Ariel Ekblaw

Enrollment: Limited: First come, first served (no advance sign-up)
Attendance: Participants welcome at individual sessions

  

With humanity at the cusp of interplanetary civilization, what are the technologies, products and laws that will engage and empower us in this exploratory period? Will space be hackable? Can space be playful? How might we design our interplanetary lives? 

Join us at the MIT Media Lab for a three-part lecture series on emerging (outer)Space Frontiers

All sessions take place in E14-244, 4-5pm. 

 

1/24: "Space Law" with guest lecturer Andy Sellars (Director of the BU Tech & Cyberlaw clinic)

 

1/26: "Space Architecture" with guest lecturers Vera Mulyani (Mars City Design) & James Wolff (Deep Space Industries)

 

2/2: "Space Bio" with Lisa Nip and John Min (researchers at the Media Lab, exploring astrobio and tardigrades)

 

 

Sponsor(s): Media Arts and Sciences
Contact: Ariel Ekblaw, SpaceFrontiersIAP@MEDIA.MIT.EDU


The Next Step in Academic Science

Prof. Adam Martin, Associate Professor of Biology

Enrollment: Unlimited: No advance sign-up
Attendance: Participants welcome at individual sessions

MIT Biology presents a selection of talks on the practice of science, naviagating academia, and balancing it all with a life outside the lab.

Sponsor(s): Biology
Contact: Adam Martin, 68-459, 617-324-0074, acmartin@mit.edu


Creating Scientific Figures with Adobe

Jan/10 Tue 02:30PM-04:00PM 68-181, Bring your laptop with Adobe Illustrator installed

Visual aids are one of the most important tools we have in communicating our research to others, be it in a publication, a talk, or a class. In the first hour, learn how to efficiently use Adobe Illustrator to make and edit figures, and work on your own figure during the second hour. Geared towards beginners, but all levels welcome ¿ we may have some tricks you don't know yet! 

Sera Thornton - Digital Learning Fellow, MITx Biology


Finding the Right Postdoctoral Position

Jan/11 Wed 01:30PM-03:00PM 68-181

Finding the Right Postdoctoral Position:  Academia and Industry

Heading toward a career in teaching or research? Come meet post-docs from academia and industry who will share their experience and advice.

Kirk Donovan - PhD, Industry Postdoc, Adam Martin - PhD, Associate Professor of Biology, Caitlin R. Ondracek - PhD, Research Postdoc, MIT for teaching, Madeleine Julie Oudin - PhD, Research Postdoc, MIT for research


Alternative Careers in Academia

Jan/12 Thu 12:00PM-01:30PM 68-181

Interested in opportunities in academia other than a faculty position? Our panelists do exciting work as senior scientists, core facility management, in health and safety and in education. Come hear about the career paths that led them there!

Elizabeth Williams - PhD, Project and Data Manager, William Rideout - PhD, Research Scientist in Jacks Lab, Wendy Salmon - Microscopy Specialist, Keck Biological Imaging Facility, Mary Ellen Wiltrout - PhD, MITx Biology, Nicolas Paquin - PhD, Deputy Director, EHS Biosafety Program


Finding and Managing a Faculty Position

Feb/03 Fri 01:30PM-03:00PM 68-180

Hear from a diverse array of faculty members on their experience finding and thriving in a faculty position.

Mary Gehring - Associate Professor of Biology, Victor Hatini - Associate Prof Developmental, Molecular & Chemical Biology, Anupama Sesham - Assistant Professor of Biology, Eliezer Calo-Velazquez - Assistant Professor of Biology