MIT: Independent Activities Period: IAP

IAP 2017



Reproducibility in Chemical Research

Rick L. Danheiser, Professor of Chemistry

Jan/19 Thu 04:00PM-05:30PM 6-120

Enrollment: Unlimited: No advance sign-up

A fundamental principle in the field of synthetic chemistry states that a synthetic chemist skilled in the art should be able to repeat a synthetic transformation with the same results as those described in published work from another laboratory. Unfortunately, all too often this is not the case. Why do many procedures prove not to be reproducible? Why do even experienced researchers encounter problems when attempting to repeat reactions described in the literature? This talk will focus on the most common causes of problems involving reproducibility in organic synthesis. The specific examples discussed will be based on experiences from my own laboratory, examples taken from the literature, and examples from procedures submitted to Organic Syntheses that I am familiar with from my service as Editor in Chief of that journal. 

Sponsor(s): Chemistry
Contact: Grace Kimball, 617-253-7271, GKIMBALL@MIT.EDU