HST.021
Musculoskeletal Pathophysiology
Dwight R. Robinson
Mon, Wed, Fri, Jan 4, 6, 8, 11, 13, 15, 20, 22, 25, 27, 29, 09-11:00am, Harvard Medical Sch., MEC 209 260 Longwood Av.Boston
Prereq: Permission of instructor
Level: H 6 units Standard A - F Grading
Growth and development of normal bone and joints, the process of mineralization, the biophysics of bone and response to stress and fracture, calcium and phosphate homeostasis and regulation by parathyroid hormone and vitamin D, and the pathogenesis of metabolic bone diseases and disease of connective tissue, joints, and muscles, with consideration of possible mechanisms and underlying metabolic derangements. Enrollment limited. (Only HST students may register under HST.020, graded P/D/F.)
Contact: Keiko Fujiwara (Oh), E25-518, x3-3609, keiko@wccf.mit.edu
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HST.146
Human Intermediary Metabolism
Charles N. Serhan
Tue, Thu, Jan 5, 7, 12, 14, 19, 21, 26, 28, 09:30-11:30am, Harvard Medical Sch., Thurs. classes thru.
Prereq: Undergraduate course in biochemistry, or permission of instructor
Level: H 6 units Graded P/D/F
See description under subject HST.147.
Contact: Keiko Fujiwara (Oh), E25-518, x3-3609, keiko@wccf.mit.edu
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HST.147
Human Intermediary Metabolism
Charles N. Serhan
Tue, Thu, Jan 5, 7, 12, 14, 19, 21, 26, 28, 09:30-11:30am, Harvard Medical Sch., Thurs. classes thru 1:30 p.
Prereq: Undergraduate subject in biochemistry or permission of instructor
Level: U 6 units Standard A - F Grading
First-year intensive subject in human biochemistry and physiological chemistry that focuses on intermediary metabolism and structures of key intermediates and enzymes important in human disease. Subject is divided into 4 groups: lipid, protein, carbohydrate, and nucleic acids. The importance of these areas is underscored with examples from diseases and clinical correlations. (Only HST students may register under HST.146, graded P/D/F.)
Contact: Keiko Fujiwara (Oh), E25-518, x3-3609, keiko@wccf.mit.edu
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HST.190/HST.191
Statistical Planning and Analysis of Biomedical Investigations
Dianne Finkelstein
Mon, Wed, Fri, Jan 4, 6, 8, 11, 13, 15, 20, 22, 25, 27, 29, 01:30-03:30pm, Harvard Medical Sch., MEC209, 260 Longwood Av.Boston
Prereq: —
Level: H 6 units Graded P/D/F
See HST.191 for description. (Only HST students may register under HST.190, graded P/D/F.)
Contact: Keiko Fujiwara (Oh), E25-518, x3-3609, keiko@wccf.mit.edu
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HST.191/HST.190
Statistical Planning and Analysis of Biomedical Investigations
Dianne Finkelstein
Mon, Wed, Fri, Jan 4, 6, 8, 11, 13, 15, 20, 25, 27, 29, 01:30-03:30pm, Harvard Medical Sch., MEC 209,260 Longwood Av.Boston
Prereq: 18.02
Level: H 6 units Standard A - F Grading
Introduces statistical logic and technique as a basis for clinical decisions and scientific inference. Students learn to perform elementary statistical calculations, use a statistics computer program (STATA), and acquire the concepts and vocabulary to read biomedical literature critically and communicate productively with statistical professionals. Includes probability theory, normal sampling, chi-square and t-tests, analysis of variance, linear regression, and survival analysis. Case studies include applications to diagnostic screening, clinical drug trials, and physiological experiments. Emphasis on experimental studies rather than epidemiology. (Only HST students may register under HST.190, graded P/D/F.)
Contact: Keiko Fujiwara (Oh), E25-518, x3-3609, keiko@wccf.mit.edu
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HST.502
Survival Skills for Emerging Researchers
Elizabeth R. Myers, Ph.D.
Mon, Tue, Jan 4, 5, 11, 12, 19, 25, 26, 02-05:00pm, E25-119, Tuesdays from 9 a.m. to noon
Prereq: —
Level: G 3 units Graded P/D/F
Provides graduate students and fellows with techniques that enhance both validity and responsible conduct in scientific practice. Divided into three categories: research methods, communication, and pathways. Study design, laboratory practice, treatment of data, human and animal research, and intellectual property are discussed under research methods. Communication section includes preparation of proposals, research papers, posters, and oral presentation. Under pathways, mentors and career options are covered. Ethics issues are integrated as appropriate to the specific topic under discussion. Satisfies the training grant requirements of the NIH for education in the responsible conduct of research.
Contact: Sara E. Wilson, BIDMC, 667-8509, sew@bihobl2.bih.harvard.edu
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