The research is organized into three programs, each involving
scientists working at different levels of analysis - cancer biology,
cell biology and computational modeling. The members of each program
interact closely to integrate these different approaches to
understand the underlying molecular and cellular processes that
govern each process and to develop testable models to drive future
understanding, analysis and intervention into those processes and
their malfunctions in cancer.
Mitogenic Signaling Networks
The overall goal of the “mitogenic signaling networks” program
is to develop high level statistical and specific physico-chemical models that
described key features of mitogenic signaling networks activated by ErbB receptors...
+ Read More
DNA Repair
Aim
1: Develop
and Implement High-Throughput Kinase Assays for
Monitoring the Signaling Response to DNA Damage.
+ Read More
Migration Signaling Networks
Identify genes/proteins that may affect invasion and
metastasis
most particularly those involved in controlling cell polarity, cytoskeletal
organization and cell motility, by genome-scale expression profiling...
+ Read More
|
