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Nikolay Zaborenko
Graduate Student

Nikolay Zaborenko

Chemical Engineering
Massachusetts Institute of Technology
66-501
25 Ames Street
Cambrdige, MA 02139

Phone: 617 258 0275
Fax: 617 258 8992
Email: nickzab@mit.edu

Education:
MS Chemical Engineering Practice, Massachusetts Institute of Technology, 2007
BS Chemical Engineering, Rutgers University – College of Engineering, 2004

Research Summary:
My research focuses on developing and applying microreactor systems for continuous-flow study and scale-up of hazardous or conventionally difficult organic chemistry processes. My work utilizes the small scales of microreactors and capabilities for continuous operation at a wide ranges of temperature and pressure to improve interphase mass transfer and greatly increase reaction rates. I have studied and improved metal-catalyzed gas-liquid reactions involving hazardous gases and  organic syntheses involving highly explosive intermediates and energetic products, as well as accelerated industrially relevant reactions by several orders of magnitude. This work will provide reaction systems and optimal conditions for performance of critical pharmaceutical and industrial chemistries where safety, speed, ease of use, and reproducibility are highly important factors.

Research Publications:
1.    Nikolay Zaborenko, Edward R. Murphy, Jason G. Kralj, Klavs F. Jensen. “Kinetic Study and Optimization of Highly Energetic Intermediated via Micromixers: Direct Multi-Step Synthesis of Sodium Nitrotetrazolate.” Industrial Engineering Chemistry Research, draft in review by advisor.
2.    Matthew W. Bedore, Nikolay Zaborenko, Timothy F. Jamison, Klavs F. Jensen. “Aminolysis of Epoxides in a Microreactor System:  A Continuous Flow Approach Towards Indacaterol and Metoprolol.” Journal of American Chemical Society, draft in review by advisor.
3.    John Goodell, Jonathan P, McMullen, Nikolay Zaborenko, Jason Maloney, Chuan-Xing Ho, Klavs F. Jensen, John Porco, Aaron Beeler. “Development of an Automated Microfluidic Reaction Platform for Multidimensional Screening: Reaction Discovery Employing Bicyclo[3.2.1]octanoid Scaffolds.” Journal of Organic Chemicstry, 2009, 16, 6169–6180.
4.    Edward R. Murphy, Tomoya Inoue, Hemantkumar R. Sahoo, Nikolay Zaborenko, Klavs F. Jensen. “Solder-Based Chip-To-Tube and Chip-To-Chip Packaging for Microfluidic Devices.” Lab on a Chip, 20077, 1309 – 1314.
5.    Edward R. Murphy, Joseph R. Martinelli, Nikolay Zaborenko, Stephen L. Buchwald, Klavs F. Jensen. “Accelerating Reactions with Microreactors at Elevated Temperatures and Pressures: Profiling Aminocarbonylation Reactions.” Angewandte Chemie, 2007, 10, pp. 1734-1737.

 

Jensenlab, 77 Massachusetts Ave, Rm 66-342, Cambridge, MA 02139 | Phone: 617.253-4589 | Last updated: October 2, 2009