Massachusetts institute of Technology  Massachusetts Institute of Technology
Department of Chemical Engineering
Jensen Research Group
 Research Areas
  - Biology
  - Chemistry
  - Energy
  - Nanomaterials
    Synthesis


 
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 Publications

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Recent Publications (2016 - 2017)

2017

K. F. Jensen, “Flow chemistry—Microreaction technology comes of age,” AIChE J., 63, 858-867 (2017). DOI: 10.1002/aic.15642

M. Peer, M. Lusardi, and K.F. Jensen, “Facile soft-templated synthesis of high-surface area and highly porous carbon nitrides,” Chem Mater 29 (4), 1496–1506 (2017) DOI: 10.1021/acs.chemmater.6b03570

A. Mijalis, D.A. Thomas, M.D. Simon, A. Adamo, R. Beaumont, K.F. Jensen, B.L. Pentelute, “Automated flow peptidesynthesis: toward amide bonds at Nature’s pace,” Nature Chemical Biology, 13, 464–466 (2017). DOI: 10.1038/nchembio.2318

X. Ding, M. P. Stewart, A. Sharei, J.C. Weaver, R.S. Langer and K.F. Jensen, “High-throughput nuclear delivery and rapid expression of DNA via mechanical and electrical cell-membrane disruption” Nature Biomed. Eng. 1, 0039 (2017). DOI: 10.1038/s41551-017-0039

O.T. Bruns, T.S. Bischof, D.K. Harris, D. Franke, Y. Shi, L. Riedemann, A. Bartelt, F.B. Jaworski, J.A. Carr, C.J. Rowlands, M.W.B. Wilson1, O. Chen, H. Wei, G.W. Hwang, D.M. Montana, I. Coropceanu, O.B. Achorn, J. Kloepper, J. Heeren, P.T.C. So, D. Fukumura, K.F. Jensen, R.K. Jain and M.G. Bawendi, “Next-generation in vivo optical imaging with short-wave infrared quantum dots,” Nature Biomed. Eng. 1, 0056 (2017). DOI: 10.1038/s41551-017-0056

N. Weeranoppanant, A. Adamo, G. Saparbaiuly, Eleanor Rose, Christian Fleury, Berthold Schenkel, and Klavs F. Jensen, “Design of multistage counter-current liquid−liquid extraction for small-scale applications,” Ind. Eng. Chem. 56 (14) 4095–4103 (2017). DOI: 10.1021/acs.iecr.7b00434

V. Sebastián, N. Zaborenko, L. Gu, and K.F. Jensen, “Microfluidic assisted synthesis of hybrid Au−Pd dumbbell-like nanostructures: Sequential addition of reagents and ultrasonic radiation,” Cryst. Growth Des. 17 (5), 2700–2710 (2017). DOI: 10.1021/acs.cgd.7b00193

C.W. Coley, R. Barzilay, T.S. Jaakkola, W.H. Green, and K.F. Jensen, “Prediction of organic reaction outcomes using machine learning,” ACS Cent. Sci. 3, 434−443 (2017). DOI: 10.1021/acscentsci.7b00064

Y. Shen, N. Weeranoppanant, L. Xie, Y. Chen, M.R. Lusardi, J. Imbrogno, M.G. Bawendi, and K.F. Jensen, “Multistage extraction platform for highly efficient and fully continuous purification of nanoparticles,” Nanoscale, 9, 7703-7 (2017). DOI: 10.1039/c7nr01826f

Y-J. Hwang, C.W. Coley, M.Abolhasani, A.L. Marzinzik, G. Koch, C. Spanka, H. Lehmann, and K.F. Jensen, “A segmented flow platform for on-demand medicinal chemistry and compound synthesis in oscillating droplets,”Chem Commu., 53, 6649-52 (2017). DOI: 10.1039/c7cc03584e

J. Zhang, K. Wang, A.R. Teixeira, K.F. Jensen, and G. Luo, “Design and scaling up of microchemical systems: A Review,” Annu. Rev. Chem. Biomol. Eng. 8, 285–305 (2017). DOI: 10.1146/annurev-chembioeng-060816-101443

H. Lin, C. Dai, T.F. Jamison, K.F. Jensen, “A rapid total synthesis of ciprofloxacin hydrochloride in continuous flow,” Angew. Chem. Int. Ed. 56, 8870-8873 (2017). DOI: 10.1002/anie.201703812

C.W. Coley, M. Abolhasani, H. K Lin, K. F. Jensen, “Material-Efficient Microfluidic Platform for Exploratory Studies of Visible-Light Photoredox Catalysis,” Angew. Chem. Int. Ed. 56, 9847-9850 (2017). DOI: 10.1002/anie.201705148

S. Lazzari, M. Abolhasani, and K,F. Jensen, “Modeling of the formation kinetics and size distribution evolution of II–VI quantum dots,” React. Chem. Eng., 2, 567–576 (2017) DOI: 10.1039/c7re00068e

C.W. Coley, R. Barzilay, W.H. Green, T.S. Jaakkola, and KF. Jensen, “Convolutional Embedding of Attributed Molecular Graphs for Physical Property Prediction,” J. Chem. Inf. Model., 57 (8), 1757–1772 (2017) DOI: 10.1021/acs.jcim.6b00601

J. Zhang, A.R. Teixeira, L.T. Kögl, L. Yang, and K.F. Jensen, “Hydrodynamics of gas–liquid flow in micropacked beds: Pressure drop, liquid holdup, and two-phase model,” AIChE J., 63, 4694–4704 (2017). DOI: 10.1002/aic.15807

J. Zhang, A.R. Teixeira, H. Zhang, and K.F. Jensen, Anal. Chem., 89, 8524−8530 (2017). DOI: 10.1021/acs.analchem.7b02264

K. Lee, H. Lin and K.F. Jensen, “Ozonolysis of quinoline and quinoline derivatives in a Corning low flow reactor,” React Chem Eng, (2017) DOI: 10.1039/c7re00084g

J. Zhang, A.R. Teixeira, and K.F. Jensen. “Automated measurements of gas-liquid mass transfer in micropacked bed reactors,” AIChE J., (2017). DOI: 10.1002/aic.15941


2016

V. Sebastian, S. Basak and K.F. Jensen, “Continuous synthesis of palladium nanorods in oxidative segmented flow.” 62 (2) 373-380 (2016). DOI 10.1002/aic.15029.

A. Kollmannsperger, A. Sharei, A. Raulf, M. Heilemann, R. Langer, K.F. Jensen, R. Wieneke, and R. Tampe, “Live-cell protein labeling with nanometer precision by cell squeezing,” Nature Comm 7, 10372 (2016). DOI: 10.1038/ncomms10372

L. Xie, Q. Zhao, K.F. Jensen, H. Kulik, “Direct Observation of Early-Stage Quantum Dot Growth Mechanisms with High-Temperature Ab Initio Molecular Dynamics” J. Phys. Chem. C, 120, 2472-2483 (2016). DOI: 10.1021/acs.jpcc.5b12091

V. Sebastian, C.D. Smith, and K.F. Jensen, “Shape-controlled continuous synthesis of metal nanostructures,“ Nanoscale, 8, 7534 - 7543 (2016). (2016),  DOI: 10.1039/c5nr08531d.

J.S. Moore, C.D. Smith, and K.F. Jensen, “Kinetic Analysis and Automated Screening of Aminocarbonylation of Aryl Halides in Flow,” React Chem Eng, 1, 272-279 (2016). DOI: 10.1039/c6re00007j

A. Adamo, R.L. Beingessner, M. Behnam, J. Chen, T.F. Jamison, K.F. Jensen, J.-C. M. Monbaliu, A.S. Myerson, E.M. Revalor, D.R. Snead, T. Stelzer, N. Weeranoppanant, S.Y. Wong, P. Zhang (authors alphabetical order), “On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system,” Science, 352 (6281) 61-66 (2016). DOI:10.1126/science.aaf1337

A.E. Fernandes, O. Riant, A.M. Jonas and K.F. Jensen, “One “Click” to controlled bifunctional supported catalysts for the Cu/TEMPO-catalyzed aerobic oxidation of alcohols,” RSC Advances, 6, 36602 – 36605 (2016).  DOI: 10.1039/c6ra05026c

J.-C. M. Monbaliu, T. Stelzer, E. Revalor, N. Weeranoppanant, K.F. Jensen, and A.S. Myerson, “Compact and integrated approach for advanced end-to-end production, purification, and aqueous formulation of lidocaine hydrochloride,” Org. Process Res. Dev. (2016). DOI: 10.1021/acs.oprd.6b00165

M. Abolhasani and K.F. Jensen, “Oscillatory multiphase flow strategy for chemistry and biology,“ Lab Chip, 16, 2775–2784 (2016). DOI: 10.1039/c6lc00728g

T.A. Shatova, S. Lathwal, M.R. Engle, H.D. Sikes, and K.F. Jensen, “Portable, constriction–expansion blood plasma separation and polymerization-based malaria detection,” Anal. Chem., 88 (15), pp 7627–7632 (2016). DOI: 10.1021/acs.analchem.6b01355

A.E. Fernandes, O. Riant, K.F. Jensen, A.M. Jonas, “Molecular engineering of trifunctional supported catalysts for the aerobic oxidation of alcohols,“ Angew. Chemie. Int. Ed. (2016). DOI: 10.1002/anie.201603673

B.J. Reizman and K.F. Jensen, “Feedback in flow for accelerated reaction development,” Acc. Chem. Res. 49, 1786−1796 (2016).  DOI: 10.1021/acs.accounts.6b00261

M. Peer, N. Weeranoppanant, A. Adamo, Y. Zhang, and K.F. Jensen, “Biphasic catalytic hydrogen peroxide oxidation of alcohols in flow: scale-up and extraction,” Org. Process Res. Dev. 20 (9), 1677–1685 (2016). DOI: 10.1021/acs.oprd.6b00234

V. Sebastian and K.F. Jensen, “Nanoengineering a library of metallic nanostructures using a single microfluidic reactor,” Nanoscale, 8, 1528 8–15295 (2016). DOI: 10.1039/c6nr04104c

Y. Mo and K.F. Jensen, “A miniature CSTR cascade for continuous flow of reactions containing solids,” React Chem Eng, 1, 501-507(2016). DOI: 10.1039/c6re00132g

B.J. Reizman, Y.-M. Wang, S.L. Buchwald, and K.F. Jensen, “Suzuki–Miyaura cross-coupling optimization enabled by automated feedback,” React Chem Eng, 1, 658-666 (2016). DOI: 10.1039/c6re00153j

L. Xie, Y. Shen, D. Franke, V, Sebastián, M.G. Bawendi, and K. F. Jensen, “Characterization of indium phosphide quantum dot growth intermediates using MALDI-TOF Mass Spectrometry,” J. Am. Chem. Soc. 138 (41), 13469–13472 (2016). DOI: 10.1021/jacs.6b06468

M.T. Saung, A. Sharei, V.A. Adalsteinsson, N. Cho, T. Kamath, C. Ruiz, J. Kirkpatrick, N. Patel, M. Mino-Kenudson, S.P. Thayer, R.S. Langer, K.F. Jensen, A. S. Liss, and J.C. Love, “A size-selective intracellular delivery platform,” Small, 12 (42) 5873–5881 (2016). DOI: 10.1002/smll.201601155

M.P. Stewart, A. Sharei, X. Ding, G. Sahay, R.S. Langer, and  K.F. Jensen, “In vitro and ex vivo strategies for intracellular delivery,” Nature 538, 183–192 (2016). DOI:10.1038/nature19764

L. Yang, M.J. Nieves-Remacha, K.F. Jensen, “Simulations and analysis of multiphase transport and reaction in segmented flow microreactors,” Chem. Eng. Sci. 169, 106–116 (2017). DOI: 10.1016/j.ces.2016.12.003

 




Jensen Research Group, 77 Massachusetts Ave, Rm 66-542, Cambridge, MA 02139 | Tel: 617.253.4589 | Updated: October 10, 2017