Maximum Entropy Construction

•  (94% of sites have at least 80% occupation by consensus amino acid)

  But, correlations do not imply causation; entropy maximization is a way of unentangling the two. (ala Martin Weigt)

  Can be validated by examining other statistics. (3pt in p17)

Next (Sequence) Outline HIV Protease Sequence Max-Ent Resistance sites Summary