KITP program on                      Evolution of Drug Resistance                    Santa Barbara, 16 August 2014

Predicting the evolution of drug resistance in HIV Protease
 

Mehran Kardar

Tom Butler, John Barton

Arup C. Chakraborty

Summary

I.       HIV: Lifecycle and drug targets               

II.     Protease: Inhibitors and Resistance                                

III.    Sequence: Diversity~Prevalence   

IV.    Retrodicting PI resistance sites    

V.    Outlook:

Acknowledgments

Tom Butler, John Barton

Arup C. Chakraborty

Karthik Sekhar, Andrej Kosmrlj, Shenshen Wang, Hanrong Chen