Maximum Entropy Construction

•  (94% of sites have at least 80% occupation by consensus amino acid)

  But, correlations do not imply causation; entropy maximization is a way of unentangling the two. (ala Martin Weigt)

  Can be validated by examining other statistics. (3pt in p17)

Next (EMF dynamics) Outline Adaptive Immunity Thymic Selection Quorum sensing Affinity Maturation Broadly neutralizing Abs EMF dynamics Max. Ent. Construction Summary