Kris C. Wood

 


Sabatini Lab, Whitehead Institute                                                                                                                  Email: kcwood@mit.edu

9 Cambridge Center                                                                                                                                               Phone: (617) 324-1835

Cambridge, MA  02142-1479                                                                                                                                     Fax: (617) 452-3566

 

 


Education

 

                Massachusetts Institute of Technology, Cambridge, MA (8/2002-5/2007)                                               

                Ph.D. in Chemical Engineering

                Research Advisors: Robert S. Langer and Paula T. Hammond

                Thesis: “Nanostructured gene and drug delivery systems based on molecular self-assembly”

                Minor: Cell Biology

 

                University of Kentucky, Lexington, KY (8/1998-5/2002)                                              

                B.S. in Chemical Engineering, Summa Cum Laude        

GPA: 4.0/4.0          Class Rank: 1/30

 

Research and Professional Experience

 

Whitehead Institute for Biomedical Research, Cambridge, MA (7/2007-Present)

NIH Postdoctoral Fellow

Research Advisor: David M. Sabatini

 

                Massachusetts Institute of Technology, Cambridge, MA (8/2002-5/2007)

                Graduate Research Assistant/Fellow, Department of Chemical Engineering

 

                Massachusetts Institute of Technology, Cambridge, MA (6/2001-8/2001)

                NSF Summer Undergraduate Research Fellow, Center for Materials Science and Engineering

 

                University of Kentucky, Lexington, KY (5/2000-5/2001; 8/2001-5/2002)                                                                            

                NSF Undergraduate Research Fellow, Department of Chemical and Materials Engineering

 

Honors

 

NIH Kirschstein/NRSA Postdoctoral Fellowship (2008-2011; accepted)

American Cancer Society Postdoctoral Fellowship (2008-2011; declined)

Ludwig Fellowship in Cancer Research, MIT (2006)

Materials Research Society Graduate Student Award (2006)

Outstanding Seminar Award, Chemical Engineering, MIT (2006)

                DuPont-MIT Fellowship (2002-03)

                UK College of Engineering Outstanding Senior Prize (2002)

                Barry M. Goldwater Scholarship for Science and Mathematics (2001-02)

UK Omega Chi Epsilon Outstanding Senior in Chemical Engineering Award (2001-02)

                UK AIChE Outstanding Junior in Chemical Engineering Award (2000-01)

                UK AIChE Donald F. Othmer Sophomore Academic Excellence Award (2000)

                UK General Chemistry Award (1998-99)

 

Publications

 

1.     Meyer, D.E.; Wood, K.; Bachas, L.G.; Bhattacharyya, D. (2004). Degradation of chlorinated organics by membrane-immobilized nanosized metals, Environ. Prog., 23, 232-242.  [PDF]

 

2.     Wood, K.C.; Boedicker, J.Q.; Lynn, D.M.; Hammond, P.T. (2005). Tunable drug release from hydrolytically degradable layer-by-layer thin films, Langmuir, 21, 1603-1609.  [PDF]

 

3.     Wood, K.C.; Little, S.R.; Langer R.; Hammond, P.T. (2005). A family of hierarchically self-assembling linear-dendritic hybrid polymers for targeted efficient gene delivery, Angew. Chem. Int. Ed. 44, 6704-6708. [PDF]

 

4.     Wood, K.C.; Chuang, H.F.; Batten, R.D.; Lynn, D.M.; Hammond, P.T. (2006). Controlling interlayer diffusion to achieve sustained, multi-agent drug delivery from layer-by-layer thin films, Proc. Natl. Acad. Sci. USA 103, 10207-10212. [PDF]

 

5.     Wood, K.C.*; Zacharia, N.S.*; Schmidt, D.J.*; Wrightman, S.; Andaya, B.J.; Hammond, P.T. (2008). Electroactive controlled release thin films, Proc. Natl. Acad. Sci. USA 105, 2280-2285.   [PDF]

 

6.        Wood, K.C.; Azarin, S.M.; Arap, W.; Pasqualini, R.; Langer, R.; Hammond, P.T. (2008). Tumor-targeted gene delivery using molecularly engineered hybrid polymers functionalized with a tumor-homing peptide, Bioconjugate Chem. 19, 403-405.  [PDF]

 

7.        Wood, K.C.; Sabatini, D.M. (2009).  Growth signaling at the nexus of stem cell life and death, Cell Stem Cell 5, 232-234.  (review) [PDF]

 

Patents

 

1.     Wood, K.C.; Langer, R.; Hammond Cunningham, P.T. Hierarchically Self-Assembling Linear-Dendritic Hybrid Polymers for Delivery of Biologically Active Agents, filed with USAPO (July 2005).

 

2.     Wood, K.C.; Zacharia, N.S.; DeLongchamp, D.M.; Hammond Cunningham, P.T. Electrochemically-Degradable Layer-by-Layer Thin Films, filed with USAPO (July 2005).

 

3.     Wood, K.C.; Chuang, H.F.; Lynn, D.M.; Hammond Cunningham, P.T.  Hydrolytically Degradable Layer-by-Layer Thin Films for Sequential and Sustained Delivery of Therapeutics, filed with USAPO (June 2006).

 

4.     O'Shaughnessy, W.S.; Loose, C.R.; Hencke, M.; Wood, K.C.; Squier, T.; Zhang, Z.  Immobilized Antimicrobial Coatings, filed with USAPO (December 2007).

 

Popular and Scientific Press Coverage

 

1.     “Doses by design,” Technology Review, September 2005.

2.     “‘Smart’ coating to deliver drugs,” BBC News, September 10, 2005.

3.     “Polymer breakthrough to boost smart drugs,” New Scientist, September 2005.

4.     “Just in time pills,” AARP Magazine, November 2005.

4.     “Nature and the fabrication of novel materials,” Materials Today, January 2005.

5.     “A synthetic solution to gene delivery,” Nature Methods, November 2005.

6.     “Smart materials could help engineer a new liver,” Technology Review, July 2006.

7.     “Programmed drug release,” Technology Review, August 2006.

 

MIT Undergraduate Students Supervised

1.     James Boedicker, (Sept. 2003 – June 2004)                      5.       Stefani Wrightman (Summer 2005)         

2.     Yun Xie (Jan. – Dec. 2004)                                                  6.       Samira Azarin (May 2005 – May 2006)

3.     Brian Andaya (NSF REU student, Summer 2004)           7.       Yamicia Connor (Sept. 2005 – May 2006)

4.     Robert Batten (Sept. 2004 – June 2005)                            8.       Lauren Tashima (Sept. 2005-Sept. 2006)

 

References

 

Available upon request