LAB
ALUMNI
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Postdoctoral
Researchers
(MIT) |
Dr. Pankaj Karande, 2006-2007. Rensselaer Polytechnic Institute, Dept. of Chemical and Biological Engineering |
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Dr. Wai Lau, 2004-2007. Bristol-Myers Squibb Adnexus Therapeutics, Waltham, MA |
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Dr. Letha Sooter, 2005-2006. West Virginia University |
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Dr.
Dasa Lipovsek, 2003-2006. Bristol-Myers Squibb Adnexus Therapeutics, Waltham, MA |
| | Dr.
Andrea Piatesi, 2004-2006. BASF, Germany |
| Dr.
Yong-Sung Kim, 2002-2004. Ajou
University, Seoul, Korea |
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Dr.
Mark J. Olsen, 2002-2004. West
Texas A&M University, Dept. of Biochemistry |
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Dr.
Jennifer R. Cochran, 2002-2004. Stanford
University, Dept.
of Bioengineering |
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Dr. Brenda A. Kellogg,
2000-2002. Bluestream Laboratories |
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Graduate Students
(MIT Ph.D) |
Jordi Mata-Fink, "Engineering of HIV gp120 by Yeast Surface Display for Neutralizing Antibody Characterization and Immunogen Design", 2012. Flagship Ventures, Cambridge, MA |
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John Rhoden, "Quantitative analysis of perivascular antibody distribution in solid tumors", 2012. Eli Lilly and Company, Indianapolis, IN |
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Shuning (Annie) Gai , "Engineering Persistent Interleukin-2 for Cancer Immunotherapy", 2012. |
| | David V. Liu , "Protein Engineering for Cancer Therapy", 2011. Stem CentRx, South San Francisco, CA |
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Christopher Pirie , "Engineering Targeted Proteins for Intracellular Delivery of Biotherapeutics ", 2011. Manus Biosynthesis, Cambridge, MA |
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Jamie Spangler, "Characterization and informed design of downregulating anti-epidermal growth factor receptor antibodies", 2011. Garcia Lab, Stanford University. |
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Michael Schmidt, "Engineering Antibodies for Improved Targeting of Solid Tumors", 2009. Eleven Biotherapeutics, Cambridge, MA |
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Kelly Davis Orcutt, "Protein Engineering for Targeted Delivery of Radionuclides to
Tumors", 2009. inviCRO, Boston, MA |
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Eileen Higham, "Overcoming Dendritic Cell-Mediated Suppression of T Cell Responses in a Prostate Tumor Environment", 2009. MedImmune |
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Margaret Ackerman , "Targeting the Tight Junction: Immunotherapy of Colon Cancer ", 2009. Assistant Professor, Thayer School of Engineering, Dartmouth College |
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Ben Hackel, "High affinity Fn3 engineering", 2009. Assistant Professor, Chemical Engineering and Materials Science, University of Minnesota. |
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Stephen Sazinsky, "Aglycosylated IgGs with enhanced immune effector function", 2008. Merrimack Pharmaceuticals, Cambridge, MA |
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Shanshan Howland, "Yeast based cancer vaccines," 2008. Renia Lab, Singapore Immunology Network, Singapore, Singapore |
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Greg Thurber, "Tumor targeting with antibodies," 2008. Assistant Professor, Chemical Engineering, University of Michigan. |
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Ginger Chao, "Anti-EGFR antibody engineering," 2007. Bristol-Myers Squibb Adnexus Therapeutics, Waltham, MA |
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Shaun M. Lippow, "Computational analysis, design, and experimental validation of antibody binding affinity improvements beyond in vivo maturation," 2007. Silver Creek Pharmaceuticals, San Francisco, CA |
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Stefan Zajic, "Improved methods and reagents for pretargeted radioimmunotherapy of cancer," 2006. Merck |
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J. Andrew Rakestraw, "A directed evolution approach to engineering recombinant protein production in S. cerevisiae," 2006. Celexion LLC , Cambridge, MA |
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David W. Colby, "Isolation, engineering, and characterization of intracellular antibodies specific for the huntingtin protein," 2005. University of Delware |
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Y. Andrew Yeung, 2005. Pfizer Rinat, San Francisco, CA |
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Jeffrey S. Swers, "Isolation and engineering of a high affinity antibody against P-selectin glycoprotein Ligand-1 (PSGL-1)," 2005. MedImmune,
Inc. |
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Balaji M. Rao, 2004. Assistant Professor Dept.
of Chemical Engineering, North
Carolina State University |
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Katarina Midelfort, "Biophysical
characterization of high affinity engineered
single chain Fv antibody fragments," 2004. Milwauke School of Engineering |
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Christilyn
P. Graff, "Antibody Engineering for Tumor
Immunotherapy," 2002. Biogen Idec,
Cambridge, MA |
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Postdoctoral
Researchers
(University of Illinois) |
Dr.
Won Shik Kwon, 1997-1998. |
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Graduate Students
(University of Illinois Ph.D) |
Bannister,
Sarah, "Increasing Heterologous Protein
Secretion from the Yeast S. cerevisiae Through
Manipulation of Cellular Redox Factors," 2000. Covington & Burling LLP |
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VanAntwerp,
Jennifer, "Affinity Maturation
of the D1.3 Antibody Using Yeast Surface
Display and Flow Cytometry," 1999. Calvin
College |
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Shusta,
Eric, "The Production of Recombinant
Immunoglobulin Superfamily Proteins in
the Yeast Saccharomyces cerevisiae," 1999. University
of Wisconsin at Madison |
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Boder,
Eric, "Molecular Engineering of
a Single Chain Fv Antibody Fragment to
Femtomolar Affinity," 1999. University
of Tennessee - Knoxville. |
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Kowalski,
Jean, "The Effect of Stability and Surface
Charge Distribution on Secretion of Bovine
Pancreatic Trypsin Inhibitor from Yeast," 1998. McKinsey & Co |
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Parekh,
Rajesh, "Disulfide Formation Kinetics
of a Model Protein (BPTI) in Yeast," 1996. McKinsey & Co. |
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Shaw,
Mark, "Gene Amplification for the Improved
Secretion of Foreign Proteins in the Yeast
Saccharomyces cerevisiae," 1995. Abbott
Laboratories |
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Arnold,
Caron, "Targeting and Translocation
Mechanisms in the Secretory Pathway of the
Yeast Saccharomyces cerevisiae," 1995. Child Psychiatry, Austin, TX |
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Robinson,
Anne, "The Role of BiP and PDI
in Foreign Protein Secretion in Yeast," 1994.
(co-advised with Prof. Douglas Lauffenburger) Tulane University. |
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