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LAB ALUMNI
 

 
Postdoctoral Students (MIT)
Dr. Pankaj Karande, 2006-2007. Rensselaer Polytechnic Institute, Dept. of Chemical and Biological Engineering
  Dr. Wai Lau, 2004-2007.
  Dr. Letha Sooter, 2005-2006.
 Dr. Dasa Lipovsek, 2003-2006. Codon Devices, Cambridge, MA
 Dr. Andrea Piatesi, 2004-2006. BASF, Germany
 Dr. Yong-Sung Kim, 2002-2004. Ajou University, Seoul, Korea
  Dr. Mark J. Olsen, 2002-2004. West Texas A&M University, Dept. of Biochemistry
  Dr. Jennifer R. Cochran, 2002-2004. Stanford University, Dept. of Bioengineering
  Dr. Brenda A. Kellogg, 2000-2002. Immunogen, Cambridge, MA

   
Graduate Students
(MIT Ph.D)
Shanshan Howland, "Yeast based cancer vaccines," 2008.
  Greg Thurber, "Tumor targeting with antibodies," 2008. Weissleder Lab, Harvard, Cambridge, MA
  Ginger Chao, "Anti-EGFR antibody engineering," 2007. Adnexus Therapeutics, Waltham, MA
  Shaun M. Lippow, "Computational analysis, design, and experimental validation of antibody binding affinity improvements beyond in vivo maturation," 2007. Codon Devices, Cambridge, MA
  Stefan Zajic, "Improved methods and reagents for pretargeted radioimmunotherapy of cancer," 2006. Merck
  J. Andrew Rakestraw, "A directed evolution approach to engineering recombinant protein production in S. cerevisiae," 2006. Codon Devices, Cambridge, MA
  David W. Colby, "Isolation, engineering, and characterization of intracellular antibodies specific for the huntingtin protein," 2005. UCSF
  Y. Andrew Yeung, 2005. Genentech
  Jeffrey S. Swers, "Isolation and engineering of a high affinity antibody against P-selectin glycoprotein Ligand-1 (PSGL-1)," 2005. MedImmune, Inc.
  Balaji M. Rao, 2004. Zandstra Lab, University of Toronto, then Dept. of Chemical Engineering, North Carolina State University
  Katarina Midelfort, "Biophysical characterization of high affinity engineered single chain Fv antibody fragments," 2004. Hellinga Lab, Duke University
  Christilyn P. Graff, "Antibody Engineering for Tumor Immunotherapy," 2002. Biogen, Cambridge, MA
   
Graduate Students
(MIT M.S. Theses)
Jason A. Burbank
   
Postdoctoral Students
(University of Illinois)
Dr. Won Shik Kwon, 1997-1998.
   
Graduate Students
(University of Illinois Ph.D)
Bannister, Sarah, "Increasing Heterologous Protein Secretion from the Yeast S. cerevisiae Through Manipulation of Cellular Redox Factors," 2000. DuPont
  VanAntwerp, Jennifer, "Affinity Maturation of the D1.3 Antibody Using Yeast Surface Display and Flow Cytometry," 1999. Calvin College
  Shusta, Eric, "The Production of Recombinant Immunoglobulin Superfamily Proteins in the Yeast Saccharomyces cerevisiae," 1999. University of Wisconsin at Madison
  Boder, Eric, "Molecular Engineering of a Single Chain Fv Antibody Fragment to Femtomolar Affinity," 1999. University of Pennsylvania
  Kowalski, Jean, "The Effect of Stability and Surface Charge Distribution on Secretion of Bovine Pancreatic Trypsin Inhibitor from Yeast," 1998. Abbott Laboratories
  Parekh, Rajesh, "Disulfide Formation Kinetics of a Model Protein (BPTI) in Yeast," 1996. McKinsey & Co.
  Shaw, Mark, "Gene Amplification for the Improved Secretion of Foreign Proteins in the Yeast Saccharomyces cerevisiae," 1995. Abbott Laboratories
  Arnold, Caron, "Targeting and Translocation Mechanisms in the Secretory Pathway of the Yeast Saccharomyces cerevisiae," 1995. Yale University School of Medicine
  Robinson, Anne, "The Role of BiP and PDI in Foreign Protein Secretion in Yeast," 1994. (co-advised with Prof. Douglas Lauffenburger) University of Delaware
   
Graduate Students
(University of Illinois M.S. Theses)
Midelfort, Katarina, "Thermodynamic and Kinetic Studies of Higher Affinity Binding Single Chain Antibody Fragments Isolated by Molecular Evolution," 2000.
  Graff, Christilyn, "Design of Soluable CD20 Ectodomain for use in Affinity Maturation of an Anti-CD20 Single Chain Antibody Fragment," 2000.
  Bannister, Sarah, "Glutathione Excretion in Response to Heterologous Secretion in Saccharomyces cerevisiae," 1999.
  Shusta, Eric, "Production of Functional Single-Chain Antibody Fragments in Yeast: Increasing the Secretory Capacity of Saccharomyces cerevisiae," 1998.
  Van Antwerp, Jennifer, "Thermodynamic Characterization of Affinity Maturation: Entropic Changes Exhibited in a Higher Affinity Mutant of the D1.3 Antibody," 1997.
  Boder, Eric, "Surface Display of a Functional Single-Chain Fv Antibody Fragment," 1996.
  Kowalski, Jean, "Purification and Characterization of a Chaperone from Methanococcus jannaschii," 1995.
  Forrester, Kathy, "The Folding of Bovine Pancreatic Trypsin Inhibitor in Saccharomyces cerevisiae," 1995.
  Voegler, Anne, "Effects of Varying Kar2 Level on Heterologous Protein Secretion from Saccharomyces cerevisiae," 1995.
  Shaw, Mark, "Gene Amplification for the Improved Secretion of Foreign Proteins in Yeast," 1994.
  Parekh, Rajesh, "Expression and Secretion of Bovine Pancreatic Trypsin Inhibitor in Saccharomyces cerevisiae," 1994.
  Arnold, Caron, "The Cellular Response to Loss of Signal Recognition Particle Function in the Yeast Saccharomyces cerevisiae," 1994.
  Westerman, Russell, "Design and Construction of a Large Area Fluorescence Array Detector," 1993.
  Weber, Anne , "A Microencapsulation Technique for Isolation of Yeast Mutants Which Secrete High Levels of Foreign Proteins," 1992.
Undergraduate Students
(University of Illinois B.S. Theses)
Omueti, Katherine June 2000
Lau, Jennifer June 2000
Ludwig, Lynn June 2000
Choi, Brian June 1999
Smith, Jason, June 1998
Lu, Hang, June 1998
Elliott, Susan, June 1997
DePaz, Roberto, June 1997
Mao, Jun June 1996
Rose, Steve, June 1995
Wilhoff, Michael, June 1995
Bockhaus, Julie, June 1995
Slyman, Joe, June 1994
Yang, Wenli, June 1993
Huang, Chiting, June 1992
Benig, Vincent, June 1992
Orelik, Kristie, June 1991
Flahive, John, June 1991
Tsai, Philip, June 1990
Pack, Daniel, June 1990
Schiek, Richard, June 1990
Other University of Illinois Undergraduate Researchers Goeckner, Bryna
Hines, Victoria
Gitlin, Irina
Singh, Shamin
Yuen, Joeseph
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