Todorova T, Bock FL, Chang P. PARP13 is a post-transcriptional regulator of cellular mRNA and functions as a pro-apoptotic factor by destabilizing TRAILR4 transcript. Nature Communications. In press.

Vyas S, Matic I, Uchima L, Rood J, Zaja R, Hay RT, Ahel I, Chang P. Family-wide analysis of poly(ADP-ribose) polymerase activity. Nature Communications 2014. 5:4426 doi: 10.1038/ncomms5426 (2014). PMID:25043379

Vyas S, Chang P. New PARP targets for cancer therapy. Nature Reviews Cancer. 2014 Jun 5. doi:10.1038/nrc3748 PMID:24898058

Vyas, S. Chesarone-Cataldo M, Todorova T, Huang YH, Chang P. A systematic analysis of the PARP protein family identifies new functions critical for cell physiology. Nature Communications 2013 4:2240. PMID:23917125

Vyas S, Chang P. Dual Roles for PARP1 during Heat Shock: Transcriptional Activator and Posttranscriptional Inhibitor of Gene Expression. Mol Cell. 2013 Jan 10;49(1):1-3. PMID:23312545

Jwa M, Chang P. PARP-16 is a tail-anchored endoplasmic reticulum protein required for the PERK and IRE1alpha-mediated unfolded protein response. Nature Cell Biology 2012 Nov;14(11):1223-30. PMID:23103912

Schmitt J, Fischer U, Heisel S, Strickfaden H, Backes C, Ruggieri A, Keller A, Chang P, Meese E. GAS41 amplification results in overexpression of a new spindle pole protein. Genes Chromosomes Cancer. 2012 May 23: 10.1002/gcc.21971.

Leung AK, Todorova T, Ando Y, Chang P. Poly(ADP-ribose) Regulates Post-transcriptional Processes in the Cytoplasm. RNA Biol. 2012 May 1;9(5).

Rood JE, Leung AK, Chang P. Methods for Purification of Proteins Associated with Cellular Poly(ADP-Ribose) and PARP-Specific Poly(ADP-Ribose). Methods Mol Biol. 2011;780:153-64.

Leung AK, Vyas S, Rood JE, Bhutkar A,Sharp PA, Chang P. Poly(ADP-Ribose) Regulates Stress Responses and MicroRNA Activity in the Cytoplasm. Mol Cell. 2011 May 20;42(4):489-99.

Zhu G, Chang P, Lippard SJ. Recognition of platinum-DNA damage by poly(ADP-ribose) polymerase-1. Biochemistry. 2010 Jul 27;49(29):6177-83.

Chang P, Coughlin M, Mitchison TJ. Interaction between Poly(ADP-ribose) and NuMA Contributes to Mitotic Spindle Pole Assembly. Mol Biol Cell. 2009 Sep 16.

Chang P, Coughlin M, Mitchison TJ. Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function. Nature Cell Biology 2005 Nov;7(11):1133-9.

Chang P, Jacobson MK, Mitchison TJ. Poly(ADP-ribose) is required for spindle assembly and structure. Nature 2004 Dec 2;432(7017):645-9.

Louie RK, Bahmanyar S, Siemers KA, Votin V, Chang P, Stearns T, Nelson WJ, Barth AI. Adenomatous polyposis coli and EB1 localize in close proximity of the mother centriole and EB1 is a functional component of centrosomes. J Cell Science 2004 Mar 1;117(Pt 7):1117-28.

Chang P, Giddings TH, Winey M, Stearns T. Epsilon-tubulin is Required for Centriole Duplication and Microtubule Organization. Nature Cell Biology 2003 Jan;5(1):71-6.

Chang P, Stearns T. Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function. Nature Cell Biology 2000 Jan;2(1):30-5.

Weisblat DA, Huang FZ, Isaksen DE, Liu NJ, Chang P. The other side of the embryo: an appreciation of the non-D quadrants in leech embryos. Current Topics Developmental Biology 1999;46:105-32.



Massachusetts Institute of Technology