Todorova T, Bock FJ, Chang P. PARP13 and RNA regulation in immunity and cancer. Trends in Molecular Medicine 2015. Accepted.

Bock FJ, Todorova T, Chang P. RNA regulation by Poly(ADP-ribose) polymerases. Molecular Cell 2015. Accepted

Bock FJ, Chang P. Stress response: PARP1 911. Nature Chemical Biology 2015; 11(3):179-180. doi: 10.1038/nchembio.1756. PMID: 25689334

Todorova T, Bock FJ, Chang P. PARP13 regulates cellular mRNA post-transcriptionally and functions as a pro-apoptotic factor by destabilizing TRAILR4 transcript.  Nature Communications 2014 ;5:5362. doi: 10.1038/ncomms6362. PMID: 25382312

Vyas S, Matic I, Uchima L, Rood J, Zaja R, Hay RT, Ahel I, Chang P. Family-wide analysis of poly(ADP-ribose) polymerase activity. Nature Communications 2014 ;5:4426 doi: 10.1038/ncomms5426 (2014). PMID:25043379

Vyas S, Chang P. New PARP targets for cancer therapy. Nature Reviews Cancer 2014 ;14(7):502-9. doi: 10.1038/nrc3748PMID:24898058

Vyas, S. Chesarone-Cataldo M, Todorova T, Huang YH, Chang P. A systematic analysis of the PARP protein family identifies new functions critical for cell physiology. Nature Communications 2013 ;4:2240. PMID:23917125

Vyas S, Chang P. Dual Roles for PARP1 during Heat Shock: Transcriptional Activator and Posttranscriptional Inhibitor of Gene Expression. Molecular Cell 2013 ;49(1):1-3. PMID:23312545

Jwa M, Chang P. PARP-16 is a tail-anchored endoplasmic reticulum protein required for the PERK and IRE1alpha-mediated unfolded protein response. Nature Cell Biology 2012 ;14(11):1223-30. PMID:23103912

Schmitt J, Fischer U, Heisel S, Strickfaden H, Backes C, Ruggieri A, Keller A, Chang P, Meese E. GAS41 amplification results in overexpression of a new spindle pole protein. Genes Chromosomes Cancer 2012 ;10.1002/gcc.21971.

Leung AK, Todorova T, Ando Y, Chang P. Poly(ADP-ribose) Regulates Post-transcriptional Processes in the Cytoplasm. RNA Biology 2012 ;9(5):542-8. doi: 10.4161/rna.19899.

Rood JE, Leung AK, Chang P. Methods for Purification of Proteins Associated with Cellular Poly(ADP-Ribose) and PARP-Specific Poly(ADP-Ribose). Methods in Molecular Biology 2011 ;780:153-64.

Leung AK, Vyas S, Rood JE, Bhutkar A,Sharp PA, Chang P. Poly(ADP-Ribose) Regulates Stress Responses and MicroRNA Activity in the Cytoplasm. Molecular Cell 2011 ;42(4):489-99.

Zhu G, Chang P, Lippard SJ. Recognition of platinum-DNA damage by poly(ADP-ribose) polymerase-1. Biochemistry 2010 ;49(29):6177-83.

Chang P, Coughlin M, Mitchison TJ. Interaction between Poly(ADP-ribose) and NuMA Contributes to Mitotic Spindle Pole Assembly. Molecular Biology of the Cell 2009 ;20(21):4575-85. doi: 10.1091/mbc.E09-06-0477

Chang P, Coughlin M, Mitchison TJ. Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function. Nature Cell Biology 2005 ;7(11):1133-9.

Chang P, Jacobson MK, Mitchison TJ. Poly(ADP-ribose) is required for spindle assembly and structure. Nature 2004 ;432(7017):645-9.

Louie RK, Bahmanyar S, Siemers KA, Votin V, Chang P, Stearns T, Nelson WJ, Barth AI. Adenomatous polyposis coli and EB1 localize in close proximity of the mother centriole and EB1 is a functional component of centrosomes. Journal of Cell Science 2004 ;117(Pt 7):1117-28.

Chang P, Giddings TH, Winey M, Stearns T. Epsilon-tubulin is Required for Centriole Duplication and Microtubule Organization. Nature Cell Biology 2003 ;5(1):71-6.

Chang P, Stearns T. Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function. Nature Cell Biology 2000 ;2(1):30-5.

Weisblat DA, Huang FZ, Isaksen DE, Liu NJ, Chang P. The other side of the embryo: an appreciation of the non-D quadrants in leech embryos. Current Topics Developmental Biology 1999 ;46:105-32.



Massachusetts Institute of Technology