Videos

Using long-term imaging of GFP-PARPs, we have characterized the localization of each of the 17 PARP proteins throughout the cell cycle. Here are a few examples.

PARP-1

Time: 0:14
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PARP-2

Time: 0:14
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PARP-5a

Time: 0:17
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PARP-5b

Time: 0:14
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We are currently using these fusions to identify new PARP functions in both cell physiology, and during cell stress events

 

 

Massachusetts Institute of Technology