Recent Publications (2013)

Eltoukhy A. A., Chen, D., Alabi, C. A., Langer R.and Anderson D. G., Degradable terpolymers with alkyl side chains demonstrate enhanced gene delivery potency and nanoparticle stability, Advanced Materials, 25:  1487-1493, 2013.

Langer, R., Fuller, J. and Levin, M. Chapter III.1.10 Entrepreneurship in Biomaterials, in Biomaterials Science, 2013, 3rd Ed., pp. 1459-1472, Ratner, D., Hoffman, S. and Schoen, F. eds., Elsevier Inc., Academic Press.

Ma, M., Guo, L, Anderson, D. and Langer, R., A bio-inspired polymer composite actuator and generator driven by water gradients, Science, 339: 186-189, 2013.

Sharei, Armon, Zoldan, Janet, Adamo, Andrea., Sim, Woo-Young, Cho, Nahyun, Jackson, Emily, Mao, Shirley, Schneider, Sabine, Han, Min-Joon, Lytton-Jean, Abigail, Basto, Pamela A., Jhunjhunwala, Siddharth, Lee, Jungmin, Heller, Daniel A., Kang, Jeon Woong, Hartoularos, George C, Kim, Kwang-Soo, Anderson, Daniel G, Langer, Robert, Jensen, Klavs F., A vector-free microfluidic platform for intracellular delivery, Proceedings of the National Academy of Sciences, 110: 2082-2087, 2013.  PMCID: PMC3568376.

Heller, D., Levi, Y., Pelet, J., Doloff, J., Wallas, J., Pratt, G., Jiang, S., Sahay, G., Schroeder, A., Schroeder, J.E., Chyan, Y., Zurenko, C., Querbes, W., Manzano-Garcia, Kohane, D., Langer, R., and Anderson, D., Modular ‘click-in-emulsion’ bone-targeted nanogels, Advanced Materials, 25:  1449-1459, 2013.

Hashimoto, M., Lagner, R. and Kohane, D., Benchtop fabrication of microfluidic systems based on curable polymers with improved solvent compatibility, Lab on a Chip, 13:  252-259, 2013.

Hook, A., Scurr, D., Burley, J., Langer, R., Anderson, D., Davies, M. and Alexander, M., Analysis and prediction of defects in UV photo-inititated polymer microarrays, Journal of Materials Chemistry B, 1: 1035-1043, 2013.

Green, J., Langer, R., and Anderson, D., Combinatorial polymer and lipidoid libraries for nanomedicine, Nanobiomaterials Series, Chapter 7, in press.

Fisher, O. Z., Larson, B. L., Hill, P. S., Graupner, D., Nguyen-Kim, M-T., Kehr, N-S., Cola, L., Langer, R. and Anderson D. G. Melanin-like hydrogels derived from gallic macromers, Advanced Materials, in press. PMCID: Exempt from PMC—Non-NIH/PHS Funding

Valencia, P., Pridgen, E., Perea, B., Gadde, S., Sweeny, C., Kantoff, P., Bander, N., Lippard, S., Langer, R., Karnik, R. and Farokhzad, O., Synergistic cytotoxicity of irinotecan and cisplatin in dual drug targeted polymeric nanoparticles, Nanomedicine, in press.

Neal, R., Jean, A., Park, H., Wu, P., Hsiao, J., Engelmayr, G., Langer, R. and Freed, L., 3D elastomeric scaffolds designed with cardiac-mimetic structural and mechanical features, Tissue Engineering, in press.

Domb, A., Langer, R. Biodegradable polyanhydrides, Poly. Chem., Biodegrad. & Toxicit, in press.

Young, M., Ward, M., Khoobei, A., Lavik, E. and Langer, R., Neuroprotection of retinal ganglion cells in the DBA/2J mouse with GDNF-loaded biodegradable microspheres, Experimental Eye Research, in press.

Berry, D., Claypool, S.M., Blumberg, R.S., Kwan, C-P., Colgan, S.P., Langer, R.S. and Sasisekharan, R., dFGF2 and FGF7 enhance a FGF1 mediated autocrine signal to promote protective effects in inflammatory bowel disease, Gastroenterology, in press.

Stevenson, C., Santini, J. and Langer, R., Reservoir based drug delivery systems utilizing microtechnology, Advanced Drug Delivery Reviews, in press.

Hook, A., Scurr, D., Anderson, D., Langer, R., Williams, P., Davies, M., and Alexander, M., High throughput discovery of thermo-responsive materials using water contact angle measurements and time-of-flight secondary ion mass spectrometry, Surface and Interface Analysis, in press.

Bettinger, C. Green, J., Langer, R., Anderson, D. and Borenstein, J., Control of nanoparticle-mediated gene delivery to human endothelial cells through substrate nanotopography, ACS Nano, in press.

Haq, R., Yokoyama, S., Hawryluk, E., Jonsson, G., McHenry, K., Porter, D., Tran, T., Love, K., Langer, R., Anderson, D., Garraway, L., Duncan, L., Morton, D., Hoon, D., Song, J. and Fisher, D., BCL2A1 is a lineage-specific anti-apoptotic melanoma oncogene that confers resistance to BRAF inhibition, Proceedings of the National Academy of Sciences, in press.

Novobrantseva, T., Borodovsky, A., Wong, J., Klebanov, B., Zafari, M., Yucius, K. Ge, P., Ruda, v., Querbes, Q., Milstein, S, Speciner, L, Duncan, R., Basha, G., Cullis, P., Akinc, A., Sullivan, J., Jayaprakash, N., Jayaraman, M., Bogorad, R., Love, K., Whitehead, K., Levins, C., Manoharan, M., Swirski, P., Weissleder, R., Langer, R., Anderson, R., de Fougerolles, A., Nahrendorf, M. and Koteliansky, V., Systemic RNAi-mediated gene silencing in non-human primate and rodent myeloid cells, Molecular Therapy Nucleic Acids, in press.

Pereira, M., Ouyang, B., Sundback, C., Langer, N., Friehs, I., Mureli, S., Pomerantseva, I., McFadden, J, Mochel, M., Mwizerwa, O., del Nido, P., Sarkar, D., Masiakos, P., Langer, R., Ferreira, L. and Karp, J., A highly  tunable biocompatible and multifunctional biodegradable elastomer, Advanced Materials, in press.