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       McGovern Institute for Brain Research at MIT

McGovern Institute Symposium:
"THE BIOLOGICAL BASIS OF PSYCHIATRIC DISEASE"
Monday April 28 – Tuesday April 29, 2008

Click here to view the Symposium webcasts

Monday Morning (April 28)

Session I - Mood Disorders (Moderator, Charles Jennings)

8:00 am - 8:30 am

Breakfast served in Atrium

8:30 am - 8:45 am

Welcome/Introduction (Bob Desimone, Director of McGovern Institute)

8:45 am - 9:30 am

Trevor Robbins (Cambridge U)
Impulsivity and Compulsivity: Neurocognitive Substrates and Neuropsychiatric Implications

9:30 am - 10:15 am

David Zald (Vanderbilt U)
Dopamine and novelty: understanding the neural substrates of personality and psychopathology

10:15 am - 10:45 am

Coffee Break

10:45 am - 11:30 am

Mark Ansorge (Columbia U)
Mouse models of anxiety and depressive disorders

11:30 am - 12:15 pm

Ruth McKernan (Pfizer)
Industry perspective on drug discovery in psychiatry

12:15 pm - 1:30 pm

Lunch & posters (boxed lunch served in atrium)

Monday Afternoon (April 28)

Session II - Schizophrenia (Moderator, Ki Goosens)

1:30 pm - 2:15 pm

Cameron Carter (UC Davis)
Neuroimaging of prefrontal cortex - implications for schizophrenia

2:15 pm - 3:00 pm

Karoly Mirnics (Vanderbilt U)
Transcriptome profiling of schizophrenia: from postmortem work to model animals

3:00 pm - 3:30 pm

Coffee Break

3:30 pm - 4:15 pm

Ed Bullmore (Cambridge U & GlaxoSmithKline)
Schizophrenia as a disorder of human brain functional and structural networks

4:15 pm - 5:00 pm

Maria Karayiorgou (Columbia U)
Genetic mouse models of schizophrenia

5:00 pm - 6:00 pm

Reception & bar

Tuesday Morning (April 29)

Session III - Mood Disorders (Moderator, Ki Goosens)

8:30 am - 9:00 am

Breakfast served in Atrium

9:00 am - 9:45 am

Sonia Lupien (McGill U)
Stress, glucocorticoids and the human brain

9:45 am - 10:30 am

Greg Quirk (U of Puerto Rico)
Mechanisms of fear learning and extinction in rodents

10:30 am - 11:00 am

Coffee Break

11:00 am - 11:45 am

Husseini Manji (NIMH)
Neural Plasticity and Mechanisms of Mood Disorders

11:45 am - 12:30 pm

James Blair (NIMH)
Violence and Victims: Dysfunction in the interaction of the amygdala and ventromedial frontal cortex in psychopathy and PTSD

12:30 pm - 1:30 pm

Lunch & posters (boxed lunch served in atrium)

Tuesday Afternoon (April 29)

Session IV - Schizophrenia (Moderator, John Gabrieli)

1:30 pm - 2:15 pm

Guoping Feng (Duke University Medical Center)
Synaptic and circuitry mechanisms of obsessive compulsive-like behaviors in mice

2:15 pm - 3:00 pm

Andreas Meyer-Lindenberg (Central Institute of Mental Health, Mannheim)
Neuroimaging and genetics - endophenotypes for psychiatric disease

3:00 pm - 3:30 pm

Coffee Break

3:30 pm - 4:15 pm

Joe Coyle (McLean Hospital & Harvard Med School)
The glutamate hypothesis of schizophrenia

4:15 pm - 5:00 pm

Akira Sawa (Johns Hopkins U)
Ttranslational approach for schizophrenia: animal models and human tissues

5:00 pm - 6:00 pm

Reception & Bar in Atrium


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