The mechanobiology LAB

An overriding objective of the Mechanobiology Lab is to elucidate the fundamental nature of how cells sense and respond to mechanical stimuli, and to employ the principles revealed by these studies to seek new treatments for vascular disease and to develop tissue constructs for drug and toxicity screening.Both experimental and computational approaches are employed in a manner that encourages the constant interplay between the two for purposes of model validation, direct measurement of critical parameters, and identifying new hypotheses to be tested through experiment. Our research group is physically located partly at MIT and partly at the SMART BioSyM center in Singapore and we work on 4 broad areas as shown below.