Mark R. Gillrie, MD PhD Visiting Scientist Email: mgillrie@mit.eduFocus group: Department: Biological Engineering Hometown: Undergrad: |
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| Research summary:
The presence of metastasis and infection are major determinants of survival in cancer patients. Despite the importance of both processes, we do not know whether common pathways exist for these frequent complications of cancer. My research is focused on how tumor-derived exosomes, small 20-150nm packages, are released from tumor cells and alter the host immune system in 3D human tissue models of cancer. I am specifically interested in how tumor-derived exosomes alter white blood cell and vascular function to increase metastasis and infection. We hope that by identifying mechanisms in both processes, we can target common pathways to improve outcomes in cancer patients.
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Research achivement: Google Scholar Link |
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