priority2meme

Usage:

priority2meme [options] <matrix file>

Description

Convert an PRIORITY matrix file into a MEME motif file suitable for use with MEME Suite programs.

Input

Matrix File

A PRIORITY file describes a motif in terms of a position weight matrix.

Output

Writes MEME motif format to standard output.

A probability matrix and optionally a log-odds matrix are output for each motif in the file. The probability matrix is computed using pseudo-counts consisting of the background frequency (see -bg, below) multiplied by the total pseudocounts (see -pseudo, below). The log-odds matrix uses the background frequencies in the denominator and is log base 2.

Options

Option Parameter Description Default Behaviour
General Options
-numbersUse a number based on the position in the input instead of the PRIORITY matrix motif name as the motif identifier.The PRIORITY matrix motif name is used as the motif identifier.
-bgbackground fileThe background file should be a Markov background model. It contains the background frequencies of letters use for assigning pseudocounts. The background frequencies will be included in the resulting MEME file.Uses uniform background frequencies.
-pseudototal pseudocountsAdd total pseudocounts times letter background to each frequency.No pseudocount is added.
-logoddsInclude a log-odds matrix in the output. This is not required for versions of the MEME Suite ≥ 4.7.0.The log-odds matrix is not included in the output.
-urlwebsiteThe provided website URL will be stored with the motif and this can be used by MEME Suite programs to provide a direct link to that information in their output. If website contains the keyword MOTIF_NAME the motif name is substituted in place of MOTIF_NAME in the output.
For example if the url is
http://big-box-of-motifs.com/motifs/MOTIF_NAME.html
and the motif name is motif_name, the motif will contain a link to
http://big-box-of-motifs.com/motifs/motif_name.html
The output does not include a URL with the motifs.