Publications

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“Concise and Enantioselective Total Synthesis of (−)-Mehranine, (−)-Methylenebismehranine, and Related Aspidosperma Alkaloids.” Mewald, M.; Medley, J. W.; Movassaghi, M. Angew. Chem. Int. Ed. 2014, Early View .

“Pd(II)-Catalyzed meta-C–H Olefination, Arylation, and Acetoxylation of Indolines Using a U-Shaped Template.” Yang, G.; Lindovska, P.; Zhu, D.; Kim, J.; Wang, P.; Tang, R.-Y.; Movassaghi, M.; Yu, J.-Q. J. Am. Chem. Soc. 2014, 136, 10807-10813.

“Total Synthesis, Stereochemical Assignment, and Biological Activity of All Known (−)-Trigonoliimines.” Han, S.; Morrison, K. C.; Hergenrother, P. J.; Movassaghi, M. J. Org. Chem. (Feature Article) 2014, 79, 473-486.

“Application of Diazene-Directed Fragment Assembly to the Total Synthesis and Stereochemical Assignment of (+)-Desmethyl-meso-chimonanthine and Related Heterodimeric Alkaloids ” Lathrop, S. P.; Movassaghi, M. Chem. Sci. 2014, 5, 333-340.

“Synthesis and Anticancer Activity of all known (−)-Agelastatin Alkaloids.” Han, S.; Siegel, D. S.; Morrison, K. C.; Hergenrother, P. J.; Movassaghi, M. J. Org. Chem. 2013, 78, 11970-11984.

“Synthesis of Spirocyclic Indolines by Interruption of the Bischler-Napieralski Reaction” Medley, J. W.; Movassaghi, M. Org. Lett. 2013, 15, 3614-3617.

“Concise Total Synthesis of (+)-Bionectins A and C” Coste, A.; Kim, J.; Adams, T. C.; Movassaghi, M. Chem. Sci. 2013, 4, 3191-3197.

“Synthesis and Anticancer Activity of Epipolythiodiketopiperazine Alkaloids ” Boyer, N.; Morrison, K. C.; Kim, J.; Hergenrother, P. J.; Movassaghi, M. Chem. Sci. 2013, 4, 1646-1657.

“Robinson's Landmark Synthesis of Tropinone ” Medley, J. W.; Movassaghi, M. Chem. Commun. 2013, 49, 10775-10777.

“Direct Synthesis of Azaheterocycles from N-Aryl/Vinyl Amides. Synthesis of 4-(Methylthio)-2-phenylquinazoline and 4-(4-Methoxyphenyl)-2-phenylquinoline.” Ahmad, O. K.; Medley, J. W.; Coste, A.; Movassaghi, M. Org. Synth. 2012, 89, 549-561.

“Concise Total Synthesis of (+)-Gliocladins B and C.” Boyer, N.; Movassaghi, M. Chem. Sci. 2012, 3, 1798-1803.

“Lithiation and Electrophilic Substitution of Dimethyl Triazones.” Han, S.; Siegel, D. S.; Movassaghi, M. Tetrahedron Lett. 2012, 53, 3722-3723.

“Radical Mediated Dimerization and Oxidation Reactions for the Synthesis of Complex Alkaloids.” Lathrop, S. P.; Kim, J.; Movassaghi, M. Chimia 2012, 66, 389-393.

“A Concise and Versatile Double-Cyclization Strategy for the Highly Stereoselective Synthesis and Arylative Dimerization of Aspidosperma Alkaloids.” Medley, J. W.; Movassaghi, M. Angew. Chem. Int. Ed. 2012, 51, 4572-4576.

“Preparation of IPNBSH and its Use in the Pd-Catalyzed Synthesis of Monoalkyl Diazenes. Synthesis of 9-Allylanthracene.” Willwacher, J.; Ahmad, O. K.; Movassaghi, M. Org. Synth. 2012, 89, 230-242.

“Concise Total Synthesis and Stereochemical Revision of (+)-Naseseazines A and B: Regioselective Arylative Dimerization of Diketopiperazine Alkaloids.” Kim, J.; Movassaghi, M. J. Am. Chem. Soc. 2011, 133, 14940-14943.

“Directed Heterodimerization: Stereocontrolled Assembly via Solvent-Caged Unsymmetrical Diazene Fragmentation.” Movassaghi, M.; Ahmad, O. K.; Lathrop, S. P. J. Am. Chem. Soc. 2011, 133, 13002-13005.

“Concise Total Synthesis and Stereochemical Revision of all (−)-Trigonoliimines.” Han, S.; Movassaghi, M. J. Am. Chem. Soc. 2011, 133, 10768-10771.

“Chemoselective and Enantioselective Oxidation of Indoles Employing Aspartyl Peptide Catalysts.” Kolundzic, F.; Noshi, M. N.; Tjandra, M.; Movassaghi, M.; Miller, S. J. J. Am. Chem. Soc. 2011, 133, 9104-9111.

“General Approach to Epipolythiodiketopiperazine Alkaloids: Total Synthesis of (+)-Chaetocins A and C and (+)-12,12'-Dideoxychetracin A.” Kim, J.; Movassaghi, M. J. Am. Chem. Soc. 2010, 132, 14376-14378.

“Total Synthesis of All (–)-Agelastatin Alkaloids.” Movassaghi, M.; Siegel, D. S.; Han, S. Chemical Science 2010, 1, 561-566.

“Dimerization of Functional Pyrroloindolizines for the Synthesis of Complex Myrmicarin Alkaloids.” Ondrus, A. E.; Kaniskan, H. U.; Movassaghi, M. Tetrahedron 2010, 66, 4784-4795.

“Total Synthesis of (–)-Himandrine.” Movassaghi, M.; Tjandra, M.; Qi, J. J. Am. Chem. Soc. 2009, 131, 9648-9650.

“Total Synthesis of (+)-11,11'-Dideoxyverticillin A.” Kim, J.; Ashenhurst, J. A.; Movassaghi, M. Science 2009, 324, 238-241.

“Reversible Dimerization of (+)-Myrmicarin 215B.” Ondrus, A. E.; Movassaghi, M. Org. Lett. 2009, 11, 2960-2963.

“Biogenetically Inspired Syntheses of Alkaloid Natural Products.” Kim, J.; Movassaghi, M. Chem. Soc. Rev. 2009, 38, 3035-3050.

“Enantioselective Total Synthesis of (–)-Acylfulvene and (–)-Irofulven.” Siegel, D. S.; Piizzi, G.; Piersanti, G.; Movassaghi, M. J. Org. Chem. 2009, 74, 9292-9304.

“Total synthesis and study of myrmicarin alkaloids.” Ondrus, A. E.; Movassaghi, M. Chem. Commun. 2009, 4151-4165.

“Synthesis of Densely Substituted Pyrimidine Derivatives.” Ahmad, O. K.; Hill, M. D.; Movassaghi, M. J. Org. Chem. 2009, 74, 8460-8463.

“Direct Dehydrative N-Pyridinylation of Amides” Medley, J. W.; Movassaghi, M. J. Org. Chem. 2009, 74, 1341-1344.

“Observations in the Synthesis of the Core of the Antitumor Illudins via an Enyne Ring Closing Metathesis Cascade.” Movassaghi, M.; Piizzi, G.; Siegel, D. S.; Piersanti, G. Tetrahedron Lett. 2009, 50, 5489-5492.

“Stereospecific Palladium-Catalyzed Entry to Monoalkyl Diazenes for Mild Allylic Reduction.” Movassaghi, M.; Ahmad, O. K. Angew. Chem. Int. Ed. 2008, 47, 8909-8912.

“Concise Total Synthesis of (+)-WIN 64821 and (–)-Ditryptophenaline.” Movassaghi, M.; Schmidt, M. A.; Ashenhurst, J. A. Angew. Chem. Int. Ed. 2008, 47, 1485-1487.

“Stereoselective Oxidative Rearrangement of 2-Aryl Tryptamine Derivatives.” Movassaghi, M.; Schmidt, M. A.; Ashenhurst, J. A. Org. Lett. 2008, 10, 4009-4012.

“Poly(ADP-ribose) Polymerase-1 Activity Facilitates the Dissociation of Nuclear Proteins from Platinum-Modified DNA.” Guggenheim, E. R.; Ondrus, A. E.; Movassaghi, M.; Lippard, S. J. Bioorg. Med. Chem. 2008, 16, 10121-10128.

“A Versatile Cyclodehydration Reaction for the Synthesis of Isoquinoline and Beta-Carboline Derivatives.” Movassaghi, M.; Hill, Matthew D. Org. Lett. 2008, 10, 3485-3488.

“New Strategies for the Synthesis of Hexahydropyrroloindole Alkaloids Inspired by Biosynthetic Hypotheses.” Schmidt, M. A.; Movassaghi, M. Synlett-(account) 2008, 313-324.

“Single-Step Synthesis of Alkynyl Imines from N-Vinyl and N-Aryl Amides. Synthesis of Phenyl-[1-phenyl-3-(trimethyl-silanyl)-prop-2-ynylidene]-amine.” Movassaghi, M.; Hill, M. D. Organic Syntheses 2008, 85, 88-95.

New Strategies for the Synthesis of Pyrimidine Derivatives.” Hill, M. D.; Movassaghi, M. Chem. Eur. J. 2008, 14, 6836-6844.

On the Interactions of N,N'-Bismesityl-imidazolin-2-yl and Alcohols.” Schmidt, M. A.; Movassaghi, M. Tetrahedron Lett. 2008, 49, 4316-4318.

Observations on the Use of Microwave Irradiation in Azaheterocycle Synthesis.” Hill, M. D.; Movassaghi, M. Tetrahedron Lett. 2008, 49, 4286-4288.

“Benzenesulfonic Acid, 2-Nitro-(1-Methylethylidene)hydrazide.” Movassaghi M., Ahmad, O. K. e-Encyclopedia of Reagents for Organic Synthesis 2008.

“Direct Synthesis of Substituted Pyrimidines and Quinazolines.” Hill, M. D.; Movassaghi, M. Synthesis 2008, 823-827.

Efficient and Stereoselective Dimerization of Pyrroloindolizine Derivatives Inspired by a Hypothesis for the Biosynthesis of Complex Myrmicarin Alkaloids.” Movassaghi, M.; Ondrus, A. E.; Chen, B. J. Org. Chem. 2007, 72, 10065-10074.

“Direct Synthesis of Pyridine Derivatives.” Movassaghi, M.; Hill, M. D.; Ahmad, O. K. J. Am. Chem. Soc. 2007, 129, 10096-10097.

“Synthesis of pyrimidines by direct condensation of amides and nitriles.” Movassaghi, M.; Hill, M. D. Nature Protocols 2007, 2, 2018-2023.

“Concise Total Synthesis of (–)-Calycanthine, (+)-Chimonanthine, and (+)-Folicanthine.” Movassaghi, M.; Schmidt, M. A. Angew. Chem. Int. Ed. 2007, 46, 3725-3728.

N-Isopropylidene-N'-2-nitrobenzenesulfonyl Hydrazine, a Reagent for Reduction of Alcohols via the Corresponding Monoalkyl Diazenes."” Movassaghi, M.; Ahmad, O. K. J. Org Chem. 2007, 72, 1838-1841 .

“Highly Stereoselective Intermolecular Formal [3+3] Cycloaddition Reaction of Cyclic Enamines and Enones.” Movassaghi, M.; Chen, B. Angew. Chem. Int. Ed. 2007, 46, 565-568.

“Synthesis of Optically Active Imidazopyridinium Salts and the Corresponding NHCs.” Schmidt, M. A.; Movassaghi, M. Tetrahedron Lett. 2007, 48, 101-104.

“Synthesis of Substituted Pyridines and Quinolines.”  Hill, M. D.; Movassaghi, M. Synthesis 2007, 1115–1119.

“Single-Step Synthesis of Pyrimidine Derivatives.” Movassaghi, M.; Hill, M. D. J. Am. Chem. Soc. 2006, 128, 14254-14255.

“Total Synthesis and Absolute Stereochemical Assignment of (+)- and ()-Galbulimima Alkaloid 13.” Movassaghi, M.; Hunt, D. K.; Tjandra, M. J. Am. Chem. Soc. 2006, 128, 8126-8127.

“Enantioselective Total Synthesis of ()-Acylfulvene and ()-Irofulven.” Movassaghi, M.; Piizzi, G.; Siegel, D. S.; Piersanti, G. Angew. Chem. Int. Ed. 2006, 45, 5859 –5863.

“Synthesis of Substituted Pyridine Derivatives via the Ruthenium–Catalyzed Cycloisomerization of 3-Azadienynes.” Movassaghi, M.; Hill, M. D. J. Am. Chem. Soc. 2006, 128, 4592-4593.

“Dimerization of (+)-myrmicarin 215B. A potential biomimetic approach to complex myrmicarin alkaloids.” Ondrus, A. E.; Movassaghi, M. Tetrahedron, 2006, 62, 5287-5297.

“Enantioselective Total Synthesis of Tricyclic Myrmicarin Alkaloids.” Movassaghi, M.; Ondrus, A. E. Org. Lett. 2005, 7, 4423-3326.

“Palladium Catalyzed Synthesis of N-Vinyl Pyrroles and Indoles.” Movassaghi, M.; Ondrus, A. E. J. Org. Chem. 2005, 7, 8638-8641.

“N-Heterocyclic Carbene-Catalyzed Amidation of Unactivated Esters with Amino Alcohols.” Movassaghi, M.; Schmidt, M. A. Org. Lett. 2005 , 7, 2453-2456.

o-Nitrobenzenesulfonylhydrazide.” Myers, A. G.; Movassaghi M. e-Encyclopedia of Reagents for Organic Synthesis 2003.

“A Direct Method for the Conversion of Terminal Epoxides into γ-Butanolides.” Movassaghi, M.; Jacobsen; E. N. J. Am. Chem. Soc. 2002, 124, 2456-2457.

“The Simplest Enzyme.” Movassaghi, M.; Jacobsen, E. N. Science 2002, 298, 1904-1905.

“Synthesis of Highly Epimerizable N-Protected α-Amino Aldehydes of High Enantiomeric Excess.” Myers, A. G.; Zhong, B.; Movassaghi, M.; Kung, D. W.; Lanman, B. A.; Kwon, S. Tetrahedron Lett. 2000, 41, 1359-1362.

“Synthesis of C-Protected α-Amino Aldehydes of High Enantiomeric Excess from Highly Epimerizable N-Protected α-Amino Aldehdyes.” Myers, A. G.; Zhong, B.; Kung, D. W.; Movassaghi, M.; Lanman, B. A.; Kwon, S. Org. Lett. 2000, 2, 3337-3340.

“Preparation of Chiral, C-Protected α-Amino Aldehydes of High Optical Purity and Their Use as Condensation Components in a Linear Synthesis Strategy.” Myers, A. G.; Kung, D. W.; Zhong, B.; Movassaghi, M.; Kwon, S. J. Am. Chem. Soc. 1999, 121, 8401-8402.

“Highly Efficient Methodology for the Reductive Coupling of Aldehyde Tosylhydrazones with Alkyllithium Reagents.” Myers, A. G.; Movassaghi, M. J. Am. Chem. Soc. 1998, 120, 8891-8892.

“Single-Step Process for the Reductive Deoxygenation of Unhindered Alcohols.” Myers, A. G.; Movassaghi, M.; Zheng, B. J. Am. Chem. Soc. 1997, 119, 8572-8573.

“Mechanistic Studies of the Free-Radical Fragmentation of Monoalkyl Diazenes.” Myers, A. G.; Movassaghi, M.; Zheng, B. Tetrahedron Lett. 1997, 38, 6569-6572.

“Preparation of the Reagent o-Nitrobenzenesulfonlylhydrazide.” Myers, A. G.; Zheng, B.; Movassaghi, M. J. Org. Chem. 1997, 62, 7507.