Koch Institute

Biologists discover how yeast cells reverse agingThe gene they found can double yeast lifespan when turned on late in life.

Robert Langer wins top chemistry awardInstitute Professor receives the ACS's Priestley Medal.

How dense is a cell?Combining an ancient principle with new technology, MIT researchers have devised a way to answer that question.

Working in harmonyMIT-designed nanoparticles communicate with each other inside the body to target tumors more efficiently.'

Finding a needle in a haystackNew sensor developed by MIT chemical engineers can detect tiny traces of explosives.

Removable ‘cloak’ for nanoparticles helps them target tumorsNew MIT particles could be used to deliver cancer drugs to nearly any type of tumor.

Understanding why lung cancer spreadsMIT biologists pinpoint a genetic change that helps tumors move to other parts of the body.

The past, present and future of cancerResearchers gather to discuss the state of their field and the potential for new treatments.

Rotch Library featuring paintings by Koch Institute architect Harry Ellenzweig

David H. Koch Institute for Integrative Cancer Research fetedMIT celebrates the official opening of the institute's new building.

Exploiting cancer cells' weaknessesTeam identifies potential drugs that enhance stress caused by too many chromosomes.

Nano-sized vaccinesNew MIT nanoparticles could lead to powerful vaccines for HIV and other diseases.

Vander Heiden wins cancer innovation awardAwarded $450,000 grant over three years

A new approach to bladder-disease treatmentImplanted device can release slow, steady dose of medicine over extended period, removing the need for repeated procedures.

Timing is everything for cancer protein p53Biologists find that restoring the gene for p53 can slow the spread of advanced lung tumors, but doesn’t help early-stage cancers.

Slideshow: the Koch Institute transforms East Campus environsCompletion of cancer-research building opens green space for community use and creates vibrant streetscape.

Direct deliveryCancer scientists believe nanoparticles could accurately target tumors, avoiding side effects.

Using the body’s own defenses to combat cancerBy engineering T cells to attack tumors, researchers hope to add a new weapon to their cancer-fighting arsenal.

Turning off cancer genesRNA interference holds much promise as a cancer treatment, but technical challenges remain.

A better way to target tumorsIn spite of slow progress toward targeting cancer drugs to individual patients, hope remains.

A new target for cancer drugsShutting down an enzyme that responds to DNA damage could boost the effects of traditional chemotherapy.

Cancer’s hiding spots revealedDiscovery that tumor cells can escape from chemotherapy could lead to new treatments that prevent relapse.

New Koch Institute building to open soonResearchers will start moving into the 365,000-square-foot building next week.

Surprising similarities between human and zebrafish tumorsNew finding that tumor cells in both species have too many chromosomes could help pinpoint genes that drive cancer development.

An unexpected twist in cancer metabolismA cancer-cell quirk could be exploited to develop new drugs that starve tumors.

A pharmacy on the back of a cellDrugs encapsulated in new MIT nanoparticles can hitch a ride to tumors on the surface of immune-system cells.

MIT’s Koch Institute in strategic partnership with Ortho-McNeil-Janssen PharmaceuticalsOrganizations will collaborate in multiple areas of oncology research and technology development.

Tackling cancer on a new frontNew program at MIT’s Koch Institute targets the growing cancer problem in India.

Rapid analysis of DNA damage now possibleTechnology offers a new way to test potential cancer drugs, detect effects of hazardous agents in our environment.

Why cancer drugs lose their powerMIT biologists show how tumors can become resistant to the commonly used chemotherapy drug cisplatin.