Koch Institute

A new target for cancer drugsShutting down an enzyme that responds to DNA damage could boost the effects of traditional chemotherapy.

Cancer’s hiding spots revealedDiscovery that tumor cells can escape from chemotherapy could lead to new treatments that prevent relapse.

New Koch Institute building to open soonResearchers will start moving into the 365,000-square-foot building next week.

Surprising similarities between human and zebrafish tumorsNew finding that tumor cells in both species have too many chromosomes could help pinpoint genes that drive cancer development.

An unexpected twist in cancer metabolismA cancer-cell quirk could be exploited to develop new drugs that starve tumors.

A pharmacy on the back of a cellDrugs encapsulated in new MIT nanoparticles can hitch a ride to tumors on the surface of immune-system cells.

MIT’s Koch Institute in strategic partnership with Ortho-McNeil-Janssen PharmaceuticalsOrganizations will collaborate in multiple areas of oncology research and technology development.

Tackling cancer on a new frontNew program at MIT’s Koch Institute targets the growing cancer problem in India.

Rapid analysis of DNA damage now possibleTechnology offers a new way to test potential cancer drugs, detect effects of hazardous agents in our environment.

Why cancer drugs lose their powerMIT biologists show how tumors can become resistant to the commonly used chemotherapy drug cisplatin.

Weighing the cellMIT biological engineers devise a way to measure, for the first time, how single cells accumulate mass.

To starve a tumorMIT’s Matthew Vander Heiden is part of a new generation of cancer researchers trying to exploit cancer cells’ strange metabolism.

New and improved RNA interferenceResearchers use RNA interference to silence multiple genes at once. The advance, which one expert calls a ‘substantial breakthrough,’ could lead to new treatments for liver diseases.

Explained: RNA interferenceExploiting the recently discovered mechanism could allow biologists to develop disease treatments by shutting down specific genes.

Nanoparticles for gene therapy improveMIT team’s nanoparticles could become a safer alternative to gene therapy delivered by viruses.

Possible origins of pancreatic cancer revealedTumors can arise from different cell types in the pancreas, depending on the circumstances, according to MIT cancer biologists.

Cancer research gets physical5-year grant from the National Cancer Institute will fund projects by physicists that give a new view of cancer cells.

Protein is linked to lung cancer developmentDrugs that inhibit the protein, which normally helps defend cells from infection, could target tumors in certain lung cancer patients.

Two from MIT elected to the Institute of MedicineProfessor of Economics Amy Finkelstein and Tyler Jacks, director of the Koch Institute, join arm of the National Academies of Science.

In Profile: Scott ManalisHis technology to weigh single cells led to an unexpected research focus: figuring out how cancerous cells escape normal growth controls.

A turning point in the struggle against cancer?Using new tools, ideas and ways of working, MIT biologists and engineers hope to change paradigm.