All living cells must coordinate protein synthesis, degradation and metabolism with fundamental biological processes, such as cell growth,
division and differentiation. Gaps in our understanding of this coordination limit our ability to treat deregulated cell growth in cancer and
to influence stem cell differentiation for regenerative therapies. To address these gaps, I aim to understand quantitatively, conceptually, and mechanistically
the dynamics of this coordination with emphasis on direct precision measurements of metabolic and protein translation and degradation rates in absolute units, molecules per cell per hours.
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