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Fall 2007 Seminar Series

MASSACHUSETTS INSTITUTE OF TECHNOLOGY
OPERATIONS RESEARCH CENTER
FALL 2007 SEMINAR SERIES

DATE: October 11
LOCATION: E40-298
TIME: 4:15pm
Reception immediately following in the ORC ConferenceRoom, E40-106

SPEAKER:
Eva Lee

TITLE
Large-Scale Optimization Strategies for Optimal Cancer Treatment Design

ABSTRACT
Treatment planning for radiation therapy is inherently complex due to the number of input parameters involved. The complexity is amplified by the uncertainty of target shapes due to organ motion, by dose estimation, by availability of biological information, and by competing multiple clinical objectives within the planning procedure. In this talk, we describe some of our experience in cancer treatment design related to these issues. Various optimization methods will be contrasted, and computational challenges will be discussed.


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