Spring 2007 Seminar Series

DATE: Thursday, April 19, 2007
LOCATION: E40-298
TIME: 4:15pm
Reception immediately following in the Philip M. Morse Reading Room, E40-106

SPEAKER:
Bruce Tidor

TITLE
Research in the Emerging Field of Computational and Systems Biology

ABSTRACT
Systems biology is an emerging field that integrates ever more high-content measurement with increasingly sophisticated computational analysis, data mining approaches, and modeling techniques to enable a new understanding of complex living systems. As such, it presents new opportunities at the interface of computation, engineering, and the physical and life sciences, and it holds the promise of challenging and enriching each participating discipline. Key problem areas include model identification, simulation, and analysis across multiple scales ranging from atoms to ecologies; mining noisy datasets of sometimes limited size to extract fundamental relationships and dependencies; and development of new experimental methodologies for making systematic measurements at a variety of different scales and for introducing systematic perturbations that reveal mechanism and test models. This talk will begin with a broad overview of the emerging field of computational and systems biology and then continue with a summary of computational research carried out in the speakers group involving biochemical networks.