The David and Edith Harris Physics Colloquium Series

fall 2015 Schedule

Thursdays - Socials: 3:30pm in 4-349 (The Pappalardo Room) // Talk: 4:00pm in 10-250 (unless otherwise noted)

SEPTEMBER 10, 2015
SUCHITRA SEBASTIAN
University of Cambridge
Host: Graduate Women in Physics

Title and abstract to be posted.

Time: 4:00 pm
Place: Room 10-250
Refreshments @ 3:30 pm in 4-349 (Pappalardo Community Room)

SEPTEMBER 17, 2015
MARKUS KLUTE
MIT
Host: TBA

Title and abstract to be posted.

Time: 4:00 pm
Place: Room 10-250
Refreshments @ 3:30 pm in 4-349 (Pappalardo Community Room)

SEPTEMBER 24, 2015
TBA
Host: TBA

Title and abstract to be posted.

Time: 4:00 pm
Place: Room 10-250
Refreshments @ 3:30 pm in 4-349 (Pappalardo Community Room)

OCTOBER 1, 2015
PAUL SCHECHTER
MIT
Host: TBA

"The Gravitational Macro- and Micro-lensing of Quasars and the Ratio of Dark to Baryonic Matter in Galaxies"

In the time since the photons of the cosmic microwave background were last scattered, the universe has grown increasingly inhomogeneous. Dark and baryonic matter, once uniformly mixed, have become progressively more segregated. Observations of the motions of stars and gas in galaxies give total masses, but do not isolate the contributions of the dark and baryonic components. Observations of the micro-lensing of multiply imaged quasars by the stars within those galaxies permits measurement of the stellar mass component. We report results from such micro-lensing observations.

Time: 4:00 pm
Place: Room 10-250
Refreshments @ 3:30 pm in 4-349 (Pappalardo Community Room)

OCTOBER 8, 2015
PAPPALARDO LECTURE
JOHN CARLSTROM

University of Chicago
Host: Robert Simcoe

Title and abstract to be posted.

Time: 4:00 pm
Place: Room 10-250
Refreshments @ 3:30 pm in 4-349 (Pappalardo Community Room)

OCTOBER 15, 2015
TBA
Host: TBA

Title and abstract to be posted.

Time: 4:00 pm
Place: Room 10-250
Refreshments @ 3:30 pm in 4-349 (Pappalardo Community Room)

OCTOBER 22, 2015
JOERG SCHMIEDMAYER
Vienna University of Technology
Host: Wolfgang Ketterle

Title and abstract to be posted.

Time: 4:00 pm
Place: Room 10-250
Refreshments @ 3:30 pm in 4-349 (Pappalardo Community Room)

OCTOBER 29, 2015
BRIAN KEATING
University of California, San Diego
Host: Andrew Friedman

Title and abstract to be posted.

Time: 4:00 pm
Place: Room 10-250
Refreshments @ 3:30 pm in 4-349 (Pappalardo Community Room)

NOVEMBER 5, 2015
GAVIN CROOKS
Lawrence Berkeley National Laboratory
Host: Physics Graduate Student Council

Title and abstract to be posted.

Time: 4:00 pm
Place: Room 10-250
Refreshments @ 3:30 pm in 4-349 (Pappalardo Community Room)

NOVEMBER 12, 2015
XIAOWEI ZHUANG
Howard Hughes Medical Institute and Harvard University
Host: Ibrahim Cissé

"Illuminating Biology at the Nanoscale with Single-Molecule and Super-Resolution Fluorescence Microscopy"

Dissecting the inner workings of a cell requires imaging methods with molecular specificity, molecular-scale resolution, and dynamic imaging capability such that molecular interactions inside the cell can be directly visualized. Fluorescence microscopy is a powerful imaging modality for investigating cells largely owning to its molecular specificity and dynamic imaging capability. However, the spatial resolution of light microscopy, classically limited by diffraction to a few hundred nanometers, is substantially larger than molecular length scales in cells, making many sub-cellular structures difficult to resolve. We developed a super-resolution fluorescence microscopy method, stochastic optical reconstruction microscopy (STORM), which breaks the diffraction limit by using photo-switchable fluorescent probes to temporally separate the spatially overlapping images of individual molecules. This approach has allowed multicolor and three-dimensional imaging of living cells with nanometer-scale resolution and enabled discoveries of novel sub-cellular structures. In this talk, I will discuss the recent technological advances and biological applications of STORM.

I will also describe a single-cell transcriptome imaging method that we recently developed. System-wide analyses of the abundance and spatial organization of RNAs in single cells promise to transform our understanding in many areas of cell and developmental biology, such as the mechanism of gene regulation, the heterogeneous behavior of cells, and the development and maintenance of cell fate. Single-molecule imaging approaches are powerful tools for counting and mapping RNA; however, the number of RNA species that can be simultaneously imaged in individual cells has been limited, making it challenging to perform transcriptomic analysis of single cells in a spatially resolved manner. To overcome this challenge, we developed a transcriptome imaging approach, multiplexed error-robust fluorescent in situ hybridization (MERFISH), which allows numerous RNA species to be localized and quantified in single cells in situ. In this talk, I will also discuss the technology development and application of MERFISH.

Time: 4:00 pm
Place: Room 10-250
Refreshments @ 3:30 pm in 4-349 (Pappalardo Community Room)

NOVEMBER 19, 2015
ALBERTO NICOLIS
Columbia University
Host: Jesse Thaler

Title and abstract to be posted.

Time: 4:00 pm
Place: Room 10-250
Refreshments @ 3:30 pm in 4-349 (Pappalardo Community Room)

DECEMBER 3, 2015
PRATHEEV SREETHARAN
CEO, Vibrant Composites Inc.
Host: Peter Fisher

Title and abstract to be posted.

Time: 4:00 pm
Place: Room 10-250
Refreshments @ 3:30 pm in 4-349 (Pappalardo Community Room)

DECEMBER 10, 2015
SELIM JOCHIM
University of Heidelberg
Host: Martin Zwierlein

Title and abstract to be posted.

Time: 4:00 pm
Place: Room 10-250
Refreshments @ 3:30 pm in 4-349 (Pappalardo Community Room)

Last updated on July 7, 2015 11:48 AM