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MIT





FACULTY AND STAFF

JEFF GORE, Assistant Professor of Physics
As of January 2010


Email:
gore@mit.edu

Phone: 617.715.4251

Address:

MIT Department of Physics
Building 13-2008
Cambridge, MA 02139

Related Links:

Gore Laboratory
Jeff Gore's Home Page
Biophysics Seminar Series

Area of Physics:

Biophysics

Jeff Gore

Research Interests

Jeff Gore uses microbes such as yeast and bacteria to experimentally probe fundamental theories in evolutionary dynamics, systems biology, and quantitative ecology.

As a Pappalardo Fellow working together with Alexander van Oudenaarden, Jeff used sucrose metabolism in yeast as a model system to study the evolution of cooperation. The conditions required for the initiation and maintenance of cooperative behaviors is a classic problem in evolutionary biology. How can cooperators survive when they can be taken advantage of by "cheaters"? In the case of sucrose metabolism, Jeff found that cooperators can survive even in the presence of cheaters because the cooperators capture a small fraction (~1%) of the sugar they create before it is shared, thus making the interaction what game theorists call a snowdrift game.

Biographical Sketch

Jeff joins the MIT Physics Department as an Assistant Professor in January 2010, after spending the previous three years in the Department as a Pappalardo Fellow. He received his PhD from the Physics Department at the University of California, Berkeley, in 2005. His graduate research in single-molecule biophysics was done in the laboratory of Carlos Bustamante, focusing on the study of twist and torque in single molecules of DNA. Jeff is excited to be starting in the Physics Department at MIT, particularly because he received his undergraduate degree from the Department in 1999.

Selected Publications

Snowdrift game dynamics and facultative cheating in yeast, Jeff Gore, Hyun Youk, and Alexander van Oudenaarden, Nature 459, 253 - 256 (2009).

The yin and yang of nature [News & Views], Jeff Gore and Alexander van Oudenaarden, Nature 457, 271 - 272 (2009).

DNA overwinds when stretched, Jeff Gore, Zev Bryant, Marcelo Nollmann, Mai U. Le, Nicholas R. Cozzarelli, and Carlos Bustamante, Nature 442, 836 - 839 (2006)

Mechanochemical analysis of DNA gyrase using rotor bead tracking, Jeff Gore, Zev Bryant, Michael D. Stone, Marcelo Nollmann, Nicholas R. Cozzarelli, and Carlos Bustamante, Nature 439, 100 - 104 (2006).

Structural transitions and elasticity from torque measurements on DNA
, Zev Bryant, Michael D. Stone, Jeff Gore, Steven B. Smith, Nicholas R. Cozzarelli, Carlos Bustamante, Nature 424, 338 (2003).