His work focuses on the development of “next generation” neuroimaging techniques designed to provide large-scale molecular and cellular information noninvasively from living brains. Much of the Jasanoff laboratory’s research involves the creation and application of MRI-detectable probes of neuronal signaling. Probes are derived from small molecules, engineered proteins, or nanoparticles that affect MRI contrast to varying extents depending on the presence of molecular targets in the brain. The Jasanoff group also uses advanced functional MRI methods, in conjunction with other physiological measurement techniques, to study systems-level neural function and plasticity animals.
Jasanoff earned an MPhil in chemistry from Cambridge University and a PhD in biophysics from Harvard University, and then became a Whitehead Fellow at the Whitehead Institute for Biomedical Research before joining the MIT faculty in 2004. He was named a Raymond and Beverly Sackler Foundation Scholar in 2004 and received the McKnight Technological Innovations in Neuroscience Award in 2006. Jasanoff was also a 2007 recipient of the Director's New Innovator Award from the National Institutes of Health.