Associate professor of biological and mechanical engineering
areas of expertise: microfluidic devices and silicon microfabrication, measuring physical properties of single cells, biomolecular detection
Scott Manalis’ laboratory develops quantitative and real-time techniques for biomolecular detection and single cell analysis. The lab uses conventional silicon processing techniques to fabricate fluidic devices and develop precision measurement methods by exploiting the unique physical properties associated with micro- and nanoscale dimensions.
As an example, it has developed a method for monitoring the mass of a single mammalian cell with a precision near ~0.01 percent. It is currently using this method to investigate how cell growth relates to progression through the division cycle, and if the response of cancer cells to pathway-directed therapeutics can be classified according to subtle changes in growth.
request an interview: Sarah McDonnell | 617-253-8923 | firstname.lastname@example.org