gnu as is really a family of assemblers. If you use (or have used) the gnu assembler on one architecture, you should find a fairly similar environment when you use it on another architecture. Each version has much in common with the others, including object file formats, most assembler directives (often called pseudo-ops) and assembler syntax.
as is primarily intended to assemble the output of the gnu C compiler gcc for use by the linker ld. Nevertheless, we've tried to make as assemble correctly everything that other assemblers for the same machine would assemble. Any exceptions are documented explicitly (refer to Chapter 9 Machine Dependent Features). This doesn't mean as always uses the same syntax as another assembler for the same architecture; for example, we know of several incompatible versions of 680x0 assembly language syntax.
Unlike older assemblers, as is designed to assemble a source program in one pass of the source file. This has a subtle impact on the .org directive (refer to Section 8.61 .org new-lc, fill).