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SAUER LAB
CURRENT LAB MEMBERS
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Sauer Lab, Massachusetts Insitute of Technology Contact: Webmaster as follows sauer-www (at) mit.edu To locate us, please use the following url: http://whereis.mit.edu/map-jpg Copyright 2006 |
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Rose Garden - MIT Main Campus
(photo taken by Brenda E. Pepe)SAUER LAB CURRENT
LAB MEMBERS
Jiejin Chen
Postdoc Associate (2009-Present)
Email (jiejinc at mit.edu)
ANNA DE REGT
Anna de Regt
Graduate Student (2010-Present)
Email (aderegt at mit.edu)
Steven Glynn
Postdoc Associate (2005-Present)
Email (seglynn at mit.edu)Glynn, S.E., Martin, A., Nager, A.R., Baker, T.A. and Sauer R.T. (2009).
Structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine. Cell, 139, 744-756.
Robert A.Grant
Research Scientist (2000-Present)
Email (ragrant at mit.edu)Roman-Hernandez, G., Grant, R.A., Sauer, R.T. & Baker, T.A. (2009) Molecular basis of substrate selection by the N-end rule adaptor protein ClpS. Proc. Natl. Acad. Sci USA 106, 8888-8893.
Wang, K.H., Roman-Hernandez, G., Grant, R.A., Sauer, R.T. & Baker, T.A. (2008) The molecular basis of N-end rule recognition. Mol. Cell 32, 406-14.
Chein, P., Grant, R.A., Sauer, R.T. & Baker, T.A. (2007) Structure and substrate specificity of an SspB ortholog: design implications for AAA+ adaptors. Structure 15, 139-145.
Sohn, J., Grant, R.A. & Sauer, R.T. (2007) Allosteric activation of DegS, a stress sensor PDZ-protease. Cell 131, 572-583.
Bolon, D.N., Grant, R.A., Baker, T.A. & Sauer, R.T. (2005) Specificity versus stability in computational protein design. Proc. Natl. Acad. Sci. USA 102, 12724-12729. pubmed. citation
Levchenko, I. Grant, R.A., Flynn, J.M., Sauer, R.T. & Baker, T.A. (2005) Versatile modes of peptide recognition by the AAA+ adaptor protein SspB. Nat. Struct. & Mol. Biol. 12, 520-525. pubmed. citation
Tabtiang, R.K., Cezairliyan, B.O., Grant, R.A, Cochrane, J.C. & Sauer, R.T. (2005) Consolidating critical binding determinants by non-cyclic rearrangement of protein secondary structure. Proc. Natl. Acad. Sci. USA 102, 2305-2309. pubmed. citation
Sauer, R.T., Bolon, D.N., Burton, B.M., Burton, R.E., Flynn, J.M., Grant, R.A., Hersch, G.L., Joshi, S.A., Kenniston, J.A., Levchenko, I., Neher, S.B., Oakes, E.S.C., Siddiqui, S.M., Wah, D.A. & Baker, T.A. (2004) Sculpting the proteome with AAA+ proteases and disassembly machines. Cell 119, 9-18. pubmed. citation
Seokhee Kim
Postdoc Associate (2008-Present )
Email (shkim115 at mit.edu )
Santiago Lima
Postdoc Associate (2008-2010) and National Institute of Health Postdoc Fellow (July 2010-Present)
Email (slima at mit.edu)RANDALL MAULDIN
Randall Mauldin
Postdoc Associate (2010-Present)
Email (rmauldin at mit.edu)
Andrew R. Nager
Graduate Student (2009-Present)
Email (andrewn at mit.edu)
Glynn, S.E., Martin, A., Nager, A.R., Baker, T.A. and Sauer R.T. (2009).
Structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine. Cell, 139, 744-756.
Brenda Ellen Pepe
Sauer Lab Administrative Lab Support (August 2003 - Present)
Email (pepebe at mit.edu)Boston College Alumnus, B.A. Class of 85' and M.Ed. 89'
Robert T. Sauer
Salvador E. Luria Professor of Biology
Principal Investigator (1978-Present)
Email (bobsauer at mit.edu )Faculty
Massachusetts Institute of Technology
Other Activities
Teaching:
Teaches Graduate Biochemistry (7.51)Topics in Protein Biochemistry (7.76).
Link for Additional Information please see
KARL SCHMITZ
Karl Schmitz
Postdoc Associate (2010-Present)
Email (schmitzk at mit.edu)
Jungsan "J" Sohn
National Institutes of Health Postdoc Fellow (2006-Present)
Email (jsohn at mit.edu)
Sohn, J. & Sauer, R.T. (2009) OMP peptides modulate the activity of DegS protease by differential binding to active and inactive conformations. Mol. Cell 33, 64-74.
Sohn, J., Grant, R.A., Sauer, R.T. (2007) Allosteric activation of DegS, a stress sensor PDZ-protease. Cell. 131 572-583
BENJAMIN STINSON
Ben Stinson
Graduate Student (2010-Present )
Email (bstinson at mit.edu )
Shankar Sundar
Graduate Student (2007-Present)
Email (ss2 at mit.edu )
Matt Wohlever
National Science Foundation
Graduate Research Fellow(2009-Present)
Email (wohlever at mit.edu )
The Links
Sauer Lab, Massachusetts Insitute of Technology
77 Massachusetts Avenue, 68-571
Cambridge, MA 02139
Telephone: 617.253.6077, Fax: 617.258.0673Contact: Webmaster as follows sauer-www (at) mit.edu
(Email format (at) = @)To locate us, please use the following url: http://whereis.mit.edu/map-jpg
Copyright 2006
