SAUER LABORATORY
CURRENT LAB MEMBERS
HOME
Jiejin Chen
Postdoc Associate (2009-Present)
Email (jiejinc at mit.edu)
Joey H. Davis
Graduate Student (2006-Present)
Email (jhdavis at mit.edu)
Davis, J.H., Baker, T.A. & Sauer, R.T. (2009) Engineering synthetic adaptors and substrates for controlled ClpXP degradation. J. Biol. Chem. 14, 21848-21855.
Steven Glynn
Postdoc Associate (2005-Present)
Email (seglynn at mit.edu)Glynn, S.E., Martin, A., Nager, A.R., Baker, T.A. and Sauer R.T. (2009).
Structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine. Cell, 139, 744-756.
Robert Grant
Research Scientist, Sauer, Baker and Yaffe Labs, (2000-Present)
Email (ragrant at mit.edu)Chein, P., Grant, R.A., Sauer, R.T. & Baker, T.A. (2007) Structure and substrate specificity of an SspB ortholog: design implications for AAA+ adaptors. Structure 15, 139-145.
Sohn, J., Grant, R.A. & Sauer, R.T. (2007) Allosteric activation of DegS, a stress sensor PDZ-protease. Cell 131, 572-583.
Bolon, D.N., Grant, R.A., Baker, T.A. & Sauer, R.T. (2005) Specificity versus stability in computational protein design. Proc. Natl. Acad. Sci. USA 102, 12724-12729. pubmed. citation
Levchenko, I. Grant, R.A., Flynn, J.M., Sauer, R.T. & Baker, T.A. (2005) Versatile modes of peptide recognition by the AAA+ adaptor protein SspB. Nat. Struct. & Mol. Biol. 12, 520-525. pubmed. citation
Tabtiang, R.K., Cezairliyan, B.O., Grant, R.A, Cochrane, J.C. & Sauer, R.T. (2005) Consolidating critical binding determinants by non-cyclic rearrangement of protein secondary structure. Proc. Natl. Acad. Sci. USA 102, 2305-2309. pubmed. citation
Sauer, R.T., Bolon, D.N., Burton, B.M., Burton, R.E., Flynn, J.M., Grant, R.A., Hersch, G.L., Joshi, S.A., Kenniston, J.A., Levchenko, I., Neher, S.B., Oakes, E.S.C., Siddiqui, S.M., Wah, D.A. & Baker, T.A. (2004) Sculpting the proteome with AAA+ proteases and disassembly machines. Cell 119, 9-18. pubmed. citation
Seokhee Kim
Postdoc Associate (2008-Present )
Email (shkim115 at mit.edu )
Mary Lee
Graduate Student (2005-Present)
Email (marylee at mit.edu)
Santiago Lima
Postdoc Associate (2008-Present)
Email (slima at mit.edu)
Andrew R. Nager
Graduate Student (2009-Present)
Email (andrewn at mit.edu)
Glynn, S.E., Martin, A., Nager, A.R., Baker, T.A. and Sauer R.T. (2009).
Structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine. Cell, 139, 744-756.
Brenda Ellen Pepe
Sauer Lab Administrative Support (August 2003 - Present)
Email (pepebe at mit.edu)
- Boston College, Chestnut Hill, Massachusetts alumnae (B.A. 1985 and M.ED.1989).
- Notary Public, Commonwealth of Massachusetts (Member, National Notary Association).
- Member, National Association of Women in Catholic Higher Education (NAWCHE).
Robert T. Sauer
Salvador E. Luria Professor of Biology
Principal Investigator (1978-Present)
Email (bobsauer at mit.edu )
Other Activities
Teaching:
Teaches Graduate Biochemistry (7.51)Topics in Protein Biochemistry (7.76).
Link for Additional Information
Dr. Robert Sauer's Department of Biology page
Rober
Saator
Jungsan "J" Sohn
National Institutes of Health Postdoc Fellow (2006-Present)
Email (jsohn at mit.edu)
Sohn, J. & Sauer, R.T. (2009) OMP peptides modulate the activity of DegS protease by differential binding to active and inactive conformations. Mol. Cell 33, 64-74.
Sohn, J., Grant, R.A., Sauer, R.T. (2007) Allosteric activation of DegS, a stress sensor PDZ-protease. Cell. 131 572-583
Shankar Sundar
Graduate Student (2007-Present)
Email (ss2 at mit.edu )
Matt Wohlever
National Science Foundation Graduate Research Fellow (2009-Present)
Email (wohlever at mit.edu )
The Links
Sauer Lab, Massachusetts Insitute of Technology
77 Massachusetts Avenue, 68-571
Cambridge, MA 02139
Telephone: 617.253.6077, Fax: 617.258.0673Contact: Webmaster as follows sauer-www (at) mit.edu
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Copyright 2006
