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Lee, M.E., Baker, T.A. & Sauer, R.T. (2010) Control of substrate gating and translocation into ClpP by channel residues and ClpX binding. J. Mol. Biol. 399, 707-718. Shin, Y., Davis, J.H., Brau, R.R., Martin, A., Kenniston, J.A., Baker, T.A., Sauer, R.T. & Lang, M.J. (2009) Single-molecule denaturation and degradation of proteins by the AAA+ ClpXP protease. Proc. Natl. Acad. Sci. USA 106, 19340-19345. Gur, E. & Sauer, R.T. (2009) Degrons in protein substrates program the speed and operating efficiency of the AAA+ Lon proteolytic machine. Proc. Natl. Acad. Sci. USA 106, 18503-18508. Glynn, S.E., Martin, A., Nager, A.R., Baker, T.A. & Sauer, R.T. (2009) Crystal structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine. Cell 139, 744-756. Barkow, S.R., Levchenko, I., Baker, T.A. & Sauer, R.T. (2009) Polypeptide translocation by the AAA+ ClpXP protease machine. Chemistry & Biology 16, 605-612. Davis, J.H., Baker, T.A. & Sauer, R.T. (2009) Engineering synthetic adaptors and substrates for controlled ClpXP degradation. J. Biol. Chem. 14, 21848-21855. Sohn, J. & Sauer, R.T. (2009) OMP peptides modulate the activity of DegS protease by differential binding to active and inactive conformations. Mol. Cell 33, 64-74. Cezairliyan, B.O. & Sauer, R.T. (2008) Control of P. aeruginosa AlgW protease cleavage of MucA by peptide signals and MucB. Mol. Micro. 72, 368-379. Moore, S.D. & Sauer, R.T. (2008) Revisiting the mechanism of macrolide-antibiotic resistance mediated by ribosomal protein L22. Proc. Natl. Acad. Sci. USA 105, 18261-18266. Yakamavich, J.A., Baker, T.A. & Sauer, R.T. (2008) Asymmetric nucleotide transactions of the HslUV protease. J. Mol. Biol. 380, 946–957. Martin, A., Baker, T.A. & Sauer, R.T. (2008) Diverse pore loops of the AAA+ ClpX machine mediate unassisted and adaptor-dependent recognition of ssrA-tagged substrates. Mol. Cell 29, 441-450. Martin, A., Baker, T.A. & Sauer, R.T. (2008) Pore loops of the AAA+ ClpX machine grip substrates to drive translocation and unfolding. Nat. Struct. Mol. Biol. 15, 1147-1151. Martin, A., Baker, T.A. & Sauer, R.T. (2008) Protein unfolding by a AAA+ protease: critical dependence on ATP-hydrolysis rates and energy landscapes. Nat. Struct. Mol. Biol. 15, 139-145. Moore, S.D., Baker, T.A. & Sauer, R.T. (2008) Forced extraction of targeted components from complex macromolecular assemblies. Proc. Natl. Acad. Sci. USA 105, 11685-11690. Gur, E. & Sauer, R.T. (2008) Recognition of misfolded proteins by Lon, a AAA+ protease. Genes Dev. 22, 2267-2277. Martin, A., Baker, T.A. & Sauer, R.T. (2007) Distinct static and dynamic interactions control ATPase-peptidase communication in a AAA+ protease. Mol. Cell 27, 41-52. Sohn, J., Grant, R.A. & Sauer, R.T. (2007) Allosteric activation of DegS, a stress sensor PDZ-protease. Cell 131, 572-583. Cezairliyan, B.O. & Sauer, R.T. (2007) Inhibition of regulated proteolysis by RseB. Proc. Natl. Acad. Sci. USA 10, 3771-3776. Farrell. C.M., Baker, T.A. & Sauer, R.T. (2007) Altered specificity of a AAA+ protease. Mol. Cell 25, 161-166. McGinness, K.E., Baker, T.A. & Sauer, R.T. (2006) Engineering controllable protein degradation. Mol. Cell 22, 701-707.
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