Today’s Spotlight features a photograph, courtesy of the researchers, of Shiyi Zhang holding a ring-shaped device (left), which can be folded into a swallowable capsule (right) for easy and safe oral delivery.
Medical devices designed to reside in the stomach have a variety of applications, including prolonged drug delivery, electronic monitoring, and weight-loss intervention. However, these devices, often created with nondegradable elastic polymers, bear an inherent risk of intestinal obstruction as a result of accidental fracture or migration. As such, they are usually designed to remain in the stomach for a limited time.
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