SMART - Singapore MIT Alliance for Research and Technology

Singapore-MIT Alliance for Research & Technology

Biosystems and Micromechanics

BioSystems and Micromechanics (BioSyM) Inter-Disciplinary Research Group

Jagath C. Rajapakse
Professor of Computer Engineering
& Director, BioInformatics Research Centre
Nanyang Technological University (NTU), Singapore


  • 2007–present Professor, Computer Engineering, NTU
  • 2007–present Director, BioInformatics Research Centre, NTU
  • 2005–2006 Visiting Professor, Biological Engineering Division, MIT, USA
  • 2002–2006 Deputy Director, BioInformatics Research Center, NTU
  • 2002 Visiting Scientist, RIKEN Brain Science Centre, Japan
  • 2001–2008 Associate Professor, School of Computer Engineering, NTU
  • 2001 Visiting Scholar, Academia Sinica, Taiwan
  • 1998–2000 Assistant Professor, School of Computer Engineering, NTU
  • 1996–1998 Visiting Scientist, Max-Planck Institute of Cognitive and Brain Sciences
  • 1993–1996 Visiting Fellow, National Institute of Mental Health, USA


  • Associate Editor, IEEE Transactions on Medical Imaging, IEEE Transactions on Computational Biology and Bioinformatics, and IEEE Transactions on Neural Networks
  • Chair, IAPR Conference on Pattern Recognition in Bioinformatics (PRIB 2007)
  • Chair, IAPR Technical Committee on Pattern Recognition in Bioinformatics
  • Most cited scientist in all fields, Thomson ISI, 2007
  • Best paper awards/nominees at CIBCB 2004, GIW 2004, ICONIP 2006
  • Best undergraduate award in electronic and telecommunication engineering, University of Moratuwa (1985)
  • Fulbright Scholarship (1987-89)

Selected Publications

  • F. X. Ivan, J. C. Rajapakse, R. E. Welsch, S. G. Rozen, T. Narasaraju, G. M. Xiong, B. P. Engelward, and V. T. K. Chow, “Differential pulmonary transcriptomic profiles in murine lungs infected with low and highly virulent influenza H3N2 viruses reveal dysregulation of TERM1 signaling, cytokines, and chemokines,” Functional and Integrative Genomics, (published on line)
  • V. R. Singh, H. Choi, E. Y. S. Yew, D. Bhattacharya, L. Yuan, C. J. R. Sheppard, J. C. Rajapakse, G. Barbastathiis, P. So, “Improving signal-to-noise ratio of structured light microscopy based on photon reassignment,” Biomedical Optical Express, Vol. 3, No. 1, pp. 206 – 214, 2012
  • W. L. Au, J. Zhou, P. Palmes, Y.-Y. Sitoh, L. C. Tan, and J. C. Rajapakse, “Levodopa and the feedback process on set-shifting in Parkinson’s disease,” Human Brain Mapping,33 (1), pp. 27-39, 2012
  • J. C. Rajapakse and P. A. Mundra, “Stability of building gene regulatory networks with sparse autoregressive models,” BMC Bioinformatics, 12, (Suppl. 13), S17, 2011
  • M. Veronica, R. E. Welsch, A. Ng, P. Matsudaira, and J.C. Rajapakse, “Correlation of cell membrane dynamics and cell motility,” BMC Bioinformatics, 12 (Suppl.13), S19, 2011
  • H. Q. Sun, M. Y. H. Low, W. J. Hsu, C. W. Tan, and J. C. Rajapakse, “Tree-structured algorithm for long weak motif discovery,” Bioinformatics, Vol. 27, No. 19, pp. 2641 – 2647, 2011
  • M. N. Nguyen, J. M. Zurada, and J. C. Rajapakse, “Towards better understanding of protein secondary structure: extracting prediction rules,” IEEE Transactions on Computational Biology and Bioinformatics, Vol. 8, No. 3, pp. 858 – 864, 2011