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Year: | 2011 | ||||
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Type of Publication: | Article | ||||||
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Journal: | Nano Letters | Volume: | 11 | ||||
Number: | 11 | Pages: | 4932-4938 | ||||
Month: | NOV 2011 | ||||||
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Note: | PT: J; TC: 3; UT: WOS:000296674700075 |
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Abstract: | The exact mechanism of angiogenesis by europium hydroxide nanorods was unclear. In this study we have showed that formation of reactive oxygen species (H(2)O(2) and O(2)center dot-) is involved in redox signaling pathways during angiogenesis, important for cardiovascular and ischemic diseases. Here we used single-walled carbon nanotube sensor array to measure the single-molecule efflux of H(2)O(2) and a HPLC method for the determination of O(2)center dot- from endothelial cells in response to proangiogenic factors. Additionally, reactive oxygen species-mediated angiogenesis using inorganic nanorods was observed in transgenic (flila:EGFP) zebrafish embryos. |
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