Research areas: |
|
Year: | 2011 | ||||
---|---|---|---|---|---|---|---|
Type of Publication: | Article | ||||||
Authors: |
|
||||||
Journal: | Proceedings of the National Academy of Sciences of the United States of America | Volume: | 108 | ||||
Number: | 21 | Pages: | 8544-8549 | ||||
Month: | MAY 24 2011 | ||||||
Note: | PT: J; TC: 8; UT: WOS:000290908000012 |
||||||
Abstract: | A class of peptides from the bombolitin family, not previously identified for nitroaromatic recognition, allows near-infrared fluorescent single-walled carbon nanotubes to transduce specific changes in their conformation. In response to the binding of specific nitroaromatic species, such peptide-nanotube complexes form a virtual "chaperone sensor," which reports modulation of the peptide secondary structure via changes in single-walled carbon nanotubes, near-infrared photoluminescence. A split-channel microscope constructed to image quantized spectral wavelength shifts in real time, in response to nitroaromatic adsorption, results in the first single-nanotube imaging of solvatochromic events. The described indirect detection mechanism, as well as an additional exciton quenching-based optical nitroaromatic detection method, illustrate that functionalization of the carbon nanotube surface can result in completely unique sites for recognition, resolvable at the single-molecule level. |
||||||
© Strano Research Group